Immunoglobulin variable regions usage by B-lymphocytes infiltrating a human breast medullary carcinoma

Immunology Letters

Volumn 65, Issue 3, 1999, Pages 143-151

  Kotlan, Beatrix ^a,b   Gruel, Nadège ^a   Zafrani, Brigitte ^a   Füredi, Gabrielle ^b   Foldi, Janos ^b   Petranyi, Gyoso G ^b   Fridman, Wolf Herman ^a   Teillaud, Jean Luc ^a  

^a INSTITUT CURIE   (France)

^b National Institute of Haematology and Immunology Budapest   (Hungary)

Author keywords

B lymphocytes; Human variable regions; Medullary breast carcinoma

Indexed keywords

DOUBLE STRANDED DNA; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; RNA; T LYMPHOCYTE RECEPTOR;

ARTICLE; B LYMPHOCYTE; BREAST CARCINOMA; CELL SUSPENSION; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTIC INFILTRATION; MEDULLARY CARCINOMA; MOLECULAR CLONING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR ASSOCIATED LEUKOCYTE;

AMINO ACID SEQUENCE; ANTIBODY DIVERSITY; B-LYMPHOCYTES; BASE SEQUENCE; BREAST NEOPLASMS; CARCINOMA, MEDULLARY; CLONING, MOLECULAR; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENE REARRANGEMENT, B-LYMPHOCYTE, LIGHT CHAIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTES, TUMOR-INFILTRATING; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; TUMOR CELLS, CULTURED;

EID: 0032974044     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2478(98)00098-4     Document Type: Article

References (33)

1. A. Van Pel, P. van der Bruggen, P.G. Coulie, V.G. Brichard, B. Lethe, B. van der Eynde, C. Uyttenhove, J.C. Renauld, T. Boon, Genes coding for tumor antigens recognized by cytolytic T-lymphocytes, in: G. Möller, (Ed.), Immunology Reviews, vol. 145, Munksgaard, Copenhagen, 1995, pp. 229-250.
2. Rosenberg S.A., Packard B.S., Aebersold P.M. et al. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma; a preliminary report. New Engl. J. Med. 319:1988;1676-1680.
3. Schwartzentruber D.J., Solomon D., Rosenberg S.A., Topalian S.L. Characterization of lymphocytes infiltrating human breast cancer: specific immune reactivity detected by measuring cytokine secretion. J. Immunother. 12:1992;1-12.
4. Theyer G., Kramer G., Assmann I. et al. Phenotypic characterization of infiltrating leukocytes in benign prostatic hyperplasia. Lab. Invest. 66:1992;96-107.
5. Whitford P., Mallon E.A., George W.D., Campbell A.M. Flow cytometric analysis of tumour infiltrating lymphocytes in breast cancer. Br. J. Cancer. 62:1990;971-975.
6. Durie F.H., Campbell A.M., Lee W.R., Damato B.E. Analysis of lymphocytic infiltration in uveal melanoma. Invest. Ophthalmol. Vis. Sci. 31:1990;2106-2110.
7. Even J., Lim A., Puisieux I. et al. T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor beta-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases. Res. Immunol. 146:1995;65-80.
8. Valteau D., Scott V., Carcelain G., Hartmann O., Escudier B., Hercend T., Triebel F. T-cell receptor repertoire in neuroblastoma patients. Cancer Res. 56:1996;362-369.
9. Farace F., Orlanducci F., Dietrich P.Y. et al. T-cell repertoire in patients with B chronic lymphocytic leukemia; evidence for multiple in vivo T-cell clonal expansions. J. Immunol. 153:1994;4281-4290.
10. Ferradini L., Mackensen A., Genevee C., Bosq J., Duvillard P., Avril M.F., Hercend T. Analysis of T-cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma; evidence for in situ T-cell clonal expansion. J. Clin. Invest. 91:1993;1183-1190.
11. Caignard A., Dietrich P.Y., Morand V. et al. Evidence for T-cell clonal expansion in a patient with squamous cell carcinoma of the head and neck. Cancer Res. 54:1994;1292-1297.
12. Gaudin C., Dietrich P.Y., Robache S. et al. In vivo local expansion of clonal T-cell subpopulations in renal cell carcinoma. Cancer Res. 55:1995;685-690.
13. Vose B.M., Moore M. Human tumor-infiltrating lymphocytes: a marker of host response. Semin. Hematol. 22:1985;27-40.
14. Whelchel J.C., Farah S.E., Mc Lean I.W., Burnier M.N. Immunohistochemistry of infiltrating lymphocytes in uveal malignant melanoma. Invest. Ophthalmol. Vis. Sci. 34:1993;2603-2606.
15. + T-cells. World J. Surg. 19:1995;352-358.
16. Punt C.J., Barbuto J.A., Zhang H., Grimes W.J., Hatch K.D., Hersh E.M. Anti-tumor antibody produced by human tumor-infiltrating and peripheral blood B-lymphocytes. Cancer Immunol. Immunother. 38:1994;225-232.
17. Barbuto J.A., Grimes W.J., Hersh E.M. Antibodies to tumor necrosis factor: a component of B-cell immune responses with a role in tumor/host interaction. Cancer Immunol. Immunother. 40:1995;31-36.
18. Zhang H., Lake D.F., Barbuto J.A., Bernstein R.M., Grimes W.J., Hersh E.M. A human monoclonal anti-melanoma single-chain Fv antibody derived from tumor-infiltrating lymphocytes. Cancer Res. 55:1995;3584-3591.
19. Ridolfi R.L., Rosen P.P., Port A., Kinne D., Mike V. Medullary carcinoma of the breast: a clinicopathologic study with 10 year follow-up. Cancer. 40:1977;1365-1385.
20. Gaffey M.J., Mills S.E., Frierson H.J., Zarbo R.J., Boyd J.C., Simpson J.F., Weiss L.M. Medullary carcinoma of the breast; identification of lymphocyte subpopulations and their significance. Modern Path. 8:1990;31-38.
21. Guigou V., Cuisinier A.M., Tonnelle C., Moinier D., Fougereau M., Fumoux F. Human immunoglobulin VH and Vκ repertoire revealed by in situ hybridization. Mol. Immunol. 27:1990;935-940.
22. Portolano S., Prummel M.F., Rapoport B., Mc Lachlan S.M. Molecular cloning and characterization of human thyroid peroxidase autoantibodies of lambda light chain type. Mol. Immunol. 32:1995;1157-1169.
23. Tomlinson I.M., Walter G., Marks J.D., Llewelyn M.B., Winter G. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:1992;776-798.
24. Marks J.D., Hoogenboom H.R., Bonnert T.P., McCafferty J., Griffiths A.D., Winter G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222:1991;581-597.
25. Larrick J.W., Wallace E.F., Coloma M.J., Bruderer U., Lang A.B., Fry K.E. Therapeutic human antibodies derived from PCR amplification of B-cell variable regions. Immunol. Rev. 130:1992;69-85.
26. D2). Hybridoma. 16:1997;335-345.
27. Giegerich G., Pette M., Meinl E., Epplen J.T., Wekerle H., Hinkkanen A. Diversity of T-cell receptor α and β chain genes expressed by human T-cells specific for similar myelin basic protein peptide/major histocompatibility complexes. Eur. J. Immunol. 22:1992;753-759.
28. van den Heynde B., Hainaut P., Herin M. et al. Presence on a human melanoma of multiple antigens recognized by autologous CTL. Int. J. Cancer. 44:1989;634-640.
29. Cuisinier A.M., Guigou V., Boubli L., Fougereau M., Tonnelle C. Preferential expression of VH5 and VH6 immunoglobulin genes in early human B-cell ontogeny. Scand. J. Immunol. 30:1989;493-497.
30. Jr. Schroeder H., Dighiero G. The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. Immunol. Today. 15:1994;288-294.
31. Shin E.K., Akamizu T., Matsuda F., Sugawa H., Fujikura J., Mori T., Honjo T. Variable regions of Ig heavy chain genes encoding antithyrotropin receptor antibodies of patients with Graves' disease. J. Immunol. 152:1994;1485-1492.
32. Williams D.G., Taylor P.C. Clonal analysis of immunoglobulin mRNA in rheumatoid arthrisis synovium: characterization of expanded IgG3 populations. Eur. J. Immunol. 27:1997;476-485.
33. Kabat, E.A., Wu, T.T., Perry, H.M., Gottesman, K.S., Foeller, C., 1991. Sequences of Proteins of Immunological Interest. National Institute of Health.