Angiotensin II type 1 and type 2 receptors bind angiotensin II through different types of epitope recognition

Journal of Hypertension

Volumn 17, Issue 3, 1999, Pages 397-404

  Miura, Shin Ichiro ^a   Karnik, Sadashiva S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Alanine modification; Angiotensin II; AT1 and AT2 receptors; Conformational states of receptors; cyclohexyl alanine

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; EPITOPE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; MOLECULAR RECOGNITION; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING;

EID: 0032973878     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199917030-00013     Document Type: Article

References (20)

1. 1 Timmermans PB, Wong PC, Chiu AT, Herblin WF, Benefield P, Carini DJ, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993; 45:205-251.
2. 2 Yamada T, Horiuchi M, Dzau VJ. Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci USA 1996; 93:156-160.
3. 3 Marshall GR, Bosshard HE, Vine WH, Glickso JD, Needleman P. Angiotensin II: conformation and interaction with the receptor. In: Wesson LG, Fanelli GM Jr (editors): Recent advances in renal physiology and pharmacology. Baltimore, Maryland: University Park Press; 1974. pp. 215-256.
4. 4 Bumpus FM, Khosla MC. Angiotensin analogs as determinants of the physiologic role of angiotensin and its metabolites. In: Genest J, Koiw E, Kuchel O (editors): Hypertension: physiology and treatment. New York: McGraw-Hill; 1977. pp. 183-201.
5. 5 Noda K, Saad Y, Kinoshita A, Boyle TP, Graham RM, Husain A, et al. Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms. J Biol Chem 1995; 270:2284-2289.
6. 1 receptor is essential for full agonism. J Biol Chem 1995; 270:12846-12850.
7. 1 receptor in agonist activation. J Biol Chem 1995; 270:28511-28514.
8. 1 angiotensin receptor is generated by angiotensin II induction. Biochemistry 1996; 35:16435-16442.
9. 9 Yamano Y, Ohyama K, Chaki S, Guo D-F, Inagami T. Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesis. Biochem Biophys Res Commun 1993; 187:1426-1431.
10. 1 receptor: gain-of-function study using gene transfer. Proc Natl Acad Sci USA 1995; 92:10663-10667.
11. 2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 1995; 95:651-657.
12. 2 receptor modulates T-type calcium current in non-differentiated NG 108-15 cells. FEBS Lett 1992, 309:161-164.
13. 13 Brechler V, Reichlin S, de Gasparo M, Bottari SP. Angiotensin II stimulates protein tyrosine phosphatase activity through a G-protein independent mechanism. Recept Channels 1994; 2:89-97.
14. 14 Bedecs K, Elbaz N, Sutren M, Masson M, Susini C, Strosberg AD, et al. Angiotensin type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase. Biochem J 1997; 325:449-454.
15. 2 receptor mediated inhibition of particulate guanylate cyclase: a link with protein tyrosine phosphatase inhibition? Recept Channels 1994; 2:79-87.
16. 16 Huang XC, Richards EM, Summners C. Mitogen-activated protein kinases in rat brain neuronal cultures are activated by angiotensin II type 1 receptors and inhibited by angiotensin II type 2 receptors. J Biol Chem 1996; 271:15635-15641.
17. 17 Ross E. G protein GTPase-activating proteins: regulation of speed, amplitude and signaling selectivity. Recent Prog Hormone Res 1993; 50:207-221.
18. 1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII. J Biol Chem 1997; 272:4245-4251.
19. 19 Samanen J, Regoli D. Structure activity relationships of peptide angiotensin II receptor agonists and antagonists. In: Ruffolo RR (editor): Angiotensin II receptors, vol 2, Medicinal chemistry series. Boca Raton, Florida: CRC Press; 1994. pp. 11-98.
20. 1A angiotensin II receptor induces its constitutive activation. J Biol Chem 1997; 272:1822-1826.