Cost-effectiveness analysis of tropisetron vs. chlorpromazine- dexamethasone in the control of acute emesis induced by highly emetogenic chemotherapy in children

Pharmacy World and Science

Volumn 21, Issue 2, 1999, Pages 60-68

  Tejedor, I ^a   Idoate, A ^a   Jimenez M ^a   Sierrasesumaga, L ^a   Giraldez J ^a  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Acute emesis; Antiemetics; Cancer chemotherapy; Chlorpromazine; Cost effectiveness analysis; Dexamethasone; Pediatric; Tropisetron

Indexed keywords

ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; CARBOPLATIN; CHLORPROMAZINE DERIVATIVE; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DACTINOMYCIN; DEXAMETHASONE; IFOSFAMIDE; METHOTREXATE; TROPISETRON;

ADOLESCENT; ARTICLE; CANCER CHEMOTHERAPY; CHILD; CHILD CARE; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG COST; DRUG EFFICACY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; SOLID TUMOR; VOMITING;

ADOLESCENT; AGE FACTORS; ANTIEMETICS; CHILD; CHILD, PRESCHOOL; CHLORPROMAZINE; COST-BENEFIT ANALYSIS; DEXAMETHASONE; HUMANS; INDOLES; SENSITIVITY AND SPECIFICITY; VOMITING;

EID: 0032973644     PISSN: 09281231     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008693706516     Document Type: Article

References (15)

1. Van Hoff J, Hockenberry-Eaton MJ, Patterson K, Hutter JJ. A survey of antiemetic use in children with cancer. AJDC 1991; 145:773-8.
2. 3 antagonist ondansetron- an effective outpatient antiemetic in cancer treatment. Arch Dis Child 1990;65:822-5.
3. Carden PA, Mitchell SL, Waters KD, Tiedemann K, Ekert H. Prevention of cyclophosphamide/cytarabine-induced emesis with ondansetron in children with leukemia. J Clin Oncol 1990;8:1531-5.
4. Sullivan MJ, Abbot GD, Robinson BA. Ondansetron antiemetic therapy for chemotherapy and radiotherapy induced vomiting in children. NZ Med J 1992;105:369-71.
5. Hachimi-Idrissi S, De Schepper J, Maurus R, Otten J. Prevention of emesis by ICS 205-930 in children receiving cytotoxic chemotherapy. Eur J Cancer 1993;29A:854-6.
6. Benoit Y. Navoban® in the prevention of nausea and vomiting in children receiving cytotoxic chemotherapy. Proceedings of the 19th Congress of the European Society of Medical Oncology; 1994 Nov 19-22; Lisbon, Portugal.
7. Holdsworth MT, Raisch DW, Duncan MH, Chavez CM, Leasure MM. Assessment of chemotherapy-induced emesis and evaluation of a reduced-dose intravenous ondansetron regimen in pediatric outpatients with leukemia. Ann Pharmacother 1995;29:16-21.
8. Gershanovich M, Kolygin B, Pirgach N. Tropisetron in the control of nausea and vomiting induced by combined cancer chemotherapy in children. Ann Oncol 1993;4(3):S35-S37.
9. Foot ABM, Hayes C. Audit of guidelines for effective control of chemotherapy and radiotherapy induced emesis. Arch Dis Child 1994;71:475-80.
10. Graham-Pole J, Weare J, Engel S, Gardner R, Mehta P, Gross S. Antiemetics in children receiving cancer chemotherapy: a double-blind prospective randomised study comparing metoclopramide with chlorpromazine. J Clin Oncol 1986;4:110-3.
11. Khan AB, Bucklew CA, Levanthal BG. Effectiveness of decadran and thorazine in prevention of nausea and vomiting induced by chemotherapy in pediatric patients (abstract). Proc Am Soc Clin Oncol 1983;2:78.
12. Madero L, Perez L, Martin N, Contra T, Ruiz MJ, Robles P. Control de la emesis inducida por quimioterapia antineoplasica en la infancia. An Esp Pedia 1991;34(3):207-10.
13. Hählen K, Quintana E, Pinkerton R, Cedar E. A randomized comparison of intravenously administered granisetron versus chlorpromazine plus dexamethasone in the prevention of ifosfamide-induced emesis in children. J Pediatr 1995;26(2): 309-13.
14. Tyc VL, Mulhern RK, Fairclough D, Ward PM, Relling MV, Congmire W. Chemotherapy induced nausea and emesis in pediatric cancer patients: external validity of child and parent emesis ratings. Abstract. J Dev Behav Pediatr 1993;14(4): 236-41.
15. Reeder CE. Overview of pharmacoeconomics and pharmaceutical outcomes evaluations. Am J Health-Syst Pharm. 1995;52(Suppl4):S5-8.