Glucose metabolism in vitro of cultured and transplanted mouse pancreatic islets microencapsulated by means of a high-voltage electrostatic field

Diabetes Care

Volumn 22, Issue SUPPL. 2, 1999, Pages

  King, Aileen ^a   Sandler, Stellan ^a   Andersson, Arne ^a   Hellerström, Claes ^a   Kulseng, Bärd ^b   Skjåk Braek, Gudmund ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; INSULIN; POLYLYSINE;

ANIMAL TISSUE; CELL GROWTH; CONFERENCE PAPER; CONTROLLED STUDY; ELECTRIC FIELD; FOREIGN BODY; GLUCOSE METABOLISM; GLUCOSE OXIDATION; HISTOPATHOLOGY; INSULIN RELEASE; MICROENCAPSULATION; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION;

ANIMALS; CELLS, CULTURED; ELECTROSTATICS; GLUCOSE; INSULIN; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED C57BL; OXIDATION-REDUCTION; PANCREAS, ARTIFICIAL;

EID: 0032971976     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (18)

1. Bretzel BG, Brendel MD: International islet transplant registry. Newsletter No. 7 6:1-20, 1996
2. Sutherland DER, Gores PF, Hering BJ, Wahoff D, McKeehen DA, Gruessner RWG: Islet transplantation: an update. Diabetes Metab Rev 12:137-150, 1996
3. Lim F, Sun AM: Microencapsulated islets as bioartificial endocrine pancreas. Science 210:908-910, 1980
4. de Vos P, Wolters GHJ, Fritschy W, van Schilfgaarde R: Obstacles in the application of microencapsulation in islet transplantation. Int J Artif Organs 16:205-212, 1993
5. Sandler S, Andersson A, Hellerström C: Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets. Endocrinology 121:1424-1431, 1987
6. Krebs HA, Henseleit K: Untersuchungen über die Harnstoffbildung im Tierkörper. Hoppe-Seylers Z Physiol Chem 210:33-66, 1932
7. Heding LG: Determination of total serum insulin (IRI) in insulin-treated patients. Diabetologia 8:260-266, 1972
8. Kissane JM, Robins E: The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system. J Biol Chem 233:18-4-188, 1958
9. Hinegardner RT: An improved fluorometric assay for DNA. Anal Biochem 39:197-201, 1971
10. Lum Z-P, Krestow M, Tai IT, Vacek I, Sun AM: Xenografts of rat islets into diabetic mice. Transplantation 53:1180-1183, 1992
11. de Vos P, Wolters GHJ, van Schilfgaarde R: Possible relationship between fibrotic overgrowth of alginate-polylysine-alginate microencapsulated pancreatic islets and the microcapsule integrity. Transplant Proc 26:782-783, 1994
12. Fritschy W, de Vos P, Groen H, Klatter FR, Pasma A, Wolters GHJ, van Schilfgaarde R: The capsular overgrowth on microencapsulated pancreatic islet grafts in streptozotocin and autoimmune diabetic rats. Transplant Int 7:264-271, 1994
13. Soon-Shiong P, Otterlie M, Skjåk-Bræk G, Smidsrod O, Heintz R, Lanza RP, Espevik T: An immunological basis for the fibrotic reaction to implanted microcapsules. Transplant Proc 23:758-759, 1991
14. Clayton HA, London NJM, Colloby PS, Bell PRF: The effect of capsule composition on the biocompatibility of alginate-poly-L-lysine capsules. J Microencapsulation 8:221-233, 1991
15. Sandler S, Andersson A, Eizirik DL, Hellerström C, Espevik T, Kulseng B, Thu B, Pipeleers DG, Skjåk-Braek G: Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation 63:1712-1718, 1997
16. Sun Y-L, Ma X, Zhou D, Vacek I, Sun AM: Porcine pancreatic islets: isolation, microencapsulation and xenotransplantation. Artif Organs 17:727-733, 1993
17. De Vos P, De Haan BJ, Wolters GHJ, Strubbe JH, Van Schilfgaarde R: Improved biocompatiblity but limited graft survival after purification of alginate for microencapsulation of pancreatic islets. Diabetologia 40:262-270, 1997
18. Weir GC, Bonner-Weir S: Scientific and political impediments to successful islet transplantation. Diabetes 46:1247-1256, 1997