A novel isoform of the smooth muscle cell differentiation marker smoothelin

Journal of Molecular Medicine

Volumn 77, Issue 2, 1999, Pages 294-298

  Krämer, Jochen ^a,b   Aguirre Arteta, Ana M ^a   Thiel, Corinna ^a   Gross, C Michael ^b   Dietz, Rainer ^b   Cardoso, M Cristina ^a   Leonhardt, Heinrich ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Actinin type actin binding domain; Cytoskeleton associated protein; Proliferative vascular disease; Smooth muscle cell differentiation; Smooth muscle cell marker

Indexed keywords

ACTIN BINDING PROTEIN; ACTININ;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOSKELETON; EMBRYO DEVELOPMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROTEIN DOMAIN; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TISSUE SPECIFICITY; VASCULAR SMOOTH MUSCLE;

EID: 0032971842     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050352     Document Type: Article

References (20)

1. Schwartz SM, Campbell GH, Campbell JH (1986) Replication of smooth muscle cells in vascular disease. Circ Res 58:427-444
2. Owens GK (1995) Regulation of differentiation of vascular smooth muscle cells. Physiol Rev 75:487-517
3. Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 103:2787-2796
4. Frid MG, Shekhonin BV, Koteliansky VE, Glukhova MA (1992) Phenotypic changes of human smooth muscle cells during development: late expression of heavy caldesmon and calponin. Dev Biol 153:185-193
5. Duband JL, Gimona M, Scatena M, Sartore S, Small JV (1993) Calponin and SM 22 as differentiation markers of smooth muscle: spatiotemporal distribution during avian embryonic development. Differentiation 55:1-11
6. Babai F, Musevi-Aghdam J, Schurch W, Royal A, Gabbiani G (1990) Coexpression of alpha-sarcomeric actin, alpha-smooth muscle actin and desmin during myogenesis in rat and mouse embryos. I. Skeletal muscle. Differentiation 44:132-142
7. Miano JM, Cserjesi P, Ligon KL, Periasamy M, Olson EN (1994) Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis. Circ Res 75:803-812
8. van der Loop FT, Schaart G, Timmer ED, Ramaekers FC, van Eys GJ (1996) Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells. J Cell Biol 134:401-411
9. van der Loop FT, Gabbiani G, Kohnen G, Ramaekers FC, van Eys GJ (1997) Differentiation of smooth muscle cells in human blood vessels as defined by smoothelin, a novel marker for the contractile phenotype. Arterioscler Thromb Vasc Biol 17:665-671
10. Engelen JJ, Esterling LE, Albrechts JC, Detera-Wadleigh SD, van Eys GJ (1997) Assignment of the human gene for smoothelin (SMTN) to chromosome 22q12 by fluorescence in situ hybridization and radiation hybrid mapping. Genomics 43:245-247
11. Wehrens XH, Mies B, Gimona M, Ramaekers FC, van Eys GJ, Small JV (1997) Localization of smoothelin in avian smooth muscle and identification of a vascular-specific isoform. FEBS Lett 405:315-320
12. van Eys GJ, Voller MC, Timmer ED, Wehrens XH, Small JV, Schalken JA, Ramaekers FC, van der Loop FT (1997) Smoothelin expression characteristics: development of a smooth muscle cell in vitro system and identification of a vascular variant. Cell Struct Funct 22:65-72
13. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403-410
14. Church GM, Gilbert W (1984) Genomic sequencing. Proc Natl Acad Sci U S A 81:1991-1995
15. Applegate D, Feng W, Green RS, Taubman MB (1994) Cloning and expression of a novel acidic calponin isoform from rat aortic vascular smooth muscle. J Biol Chem 269:10683-10690
16. Gimona M, Mital R (1998) The single CH domain of calponin is neither sufficient nor necessary for F-actin binding. J Cell Sci 111:1813-1821
17. Simons M, Leclerc G, Safian RD, Isner JM, Weir L, Baim DS (1993) Relation between activated smooth-muscle cells in coronary-artery lesions and restenosis after atherectomy. N Engl J Med 328:608-613
18. Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801-809
19. Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM (1996) Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. Proc Natl Acad Sci U S A 93:900-905
20. Holifield B, Helgason T, Jemelka S, Taylor A, Navran S, Allen J, Seidel C (1996) Differentiated vascular myocytes: are they involved in neointimal formation? J Clin Invest 97:814-825