Determination of antifilarial compound UMF-078 and its metabolites in plasma by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 724, Issue 1, 1999, Pages 147-155

  Issar, Manish ^a   Nagaraja, Nelamangala V ^a   Lal, Jawahar ^a   Paliwal, Jyoti Kumar ^a   Gupta, Ram Chandra ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Flubendazole; Methyl ( ) 5 ( amino 4 fluorobenzyl)benzimidazol 2 yl carbamate; UMF 078

Indexed keywords

ANTIFILARIAL AGENT; DRUG METABOLITE; MEBENDAZOLE; UMF 078; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL MODEL; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEMATODAL AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; MEBENDAZOLE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032971318     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(98)00544-1     Document Type: Article

References (5)

1. Ramnathan S., Nair N.K., Mansor S.M., Navratnam V. J. Chromatogr. B. 655:1994;269.
2. Microsoft Excel, Version 5.0, Microsoft Inc., USA.
3. Hartmann C., Penninckx W., Heyden Y.V., Vankeerberghen P., Massart D.L., McDowell R.D. Blume H.H., Midha K.K. Experience with Chromatographic Methods-Europe, in Bio'94, Bio-International 2, Bioavailability, Bioequivalence and Pharmacokinetic Studies. 1995;331-346 Medpharm Scientific Publishers, Stuttgart, Germany.
4. Shah V.P., Midha K.K., Dighe S., McGilveray I.J., Skelly J.P., Yacobi A., Layloff T., Viswanathan C.T., Cook C.E., McDowall R.D., Pittman K.A., Spector S. J. Pharm. Sci. 81:1992;309.
5. B.V. Atul, J.K. Paliwal, R.C. Gupta, J. Pharm. Biomed. Anal. (1998) in press.