Pharmacokinetics of progesterone administered by the oral and parenteral routes

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 44, Issue 2 SUPPL., 1999, Pages 141-147

  Stanczyk, Frank Z ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Administration, oral; Drug administration routes; Progesterone

Indexed keywords

PROGESTERONE;

CONFERENCE PAPER; DRUG ABSORPTION; DRUG DETERMINATION; DRUG FORMULATION; DRUG SALIVA LEVEL; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROGESTERONE METABOLISM; PROGESTERONE URINE LEVEL; RECTAL DRUG ADMINISTRATION; SUBLINGUAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; BIOLOGICAL ASSAY; CHEMISTRY, PHARMACEUTICAL; DRUG ADMINISTRATION ROUTES; FEMALE; HUMANS; PROGESTERONE;

EID: 0032971173     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (14)

1. Chakmakjian ZH, Zachariah NY: Bioavailability of progesterone with different modes of administration. J Reprod Med 1987;32:443-448
2. Bolaji II, Tallon DF, O'Dwyer E, et al: Assessment of bioavailability of oral micronized progesterone using a salivary progesterone enzyme immunoassay. Gynecol Endocrinol 1993; 7:101-110
3. Stanczyk FZ, Gentzschein E, Ary BA, et al: Urinary progesterone and pregnanediol: Use for monitoring progesterone treatment. J Reprod Med 1997;42:216-222
4. Nahoul K, Dehennin L, Jondet M, et al: Profiles of plasma estrogens, progesterone and their metabolites after oral or vaginal administration of estradiol or progesterone. Maturitas 1993;16:185-202
5. Stanczyk FZ, Miyakawa I, Goebelsmann U: Direct radioimmunoassay of urinary estrogen and pregnanediol glucuronides during the menstrual cycle. Am J Obstet Gynecol 1980;137:443-450
6. Simon JA, Robinson DE, Andrews MC, et al: The absorption of oral micronized progesterone: The effect of food, dose proportionality, and comparison with intramuscular progesterone. Fertil Steril 1993;60:26-33
7. Maxson WS, Hargrove JT: Bioavailability of oral micronized progesterone. Fertil Steril 1985;44:622-626
8. Nakajima ST, Gibson M: The effect of a meal on circulating steady-state progesterone levels. J Clin Endocrinol Metab 1989;69:917-919
9. Nillius SJ, Johansson EDB: Plasma levels of progesterone after vaginal, rectal, or intramuscular administration of progesterone. Am J Obstet Gynecol 1971;110:470-477
10. Miles RA, Paulson RJ, Lobo RA, et al: Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: A comparative study. Fertil Steril 1994;62:485-490
11. Fanchin R, De Ziegler D, Bergeron C, et al: Transvaginal administration of progesterone. Obstet Gynecol 1997;90: 396-401
12. Cicinelli E, Ragno G, Cagnazzo I, et al: Progesterone administration by nasal spray. Fertil Steril 1991;56:139-141
13. Hermsmyer K, Patton P, Toomey C, et al: Blood levels of progesterone achieved with a percutaneous cream in postmenopausal women (abstr). Proc of the Third International Symposium, Women's Health and Menopause, Florence, Italy, June 13-16,1998
14. Bello SM, Mezrow G, Shoupe D, et al: Administration of progesterone by use of a percutaneous gel in postmenopausal women (abstr). Proc of the Annual Meeting of the Pacific Coast Fertility Society, Indian Wells, California, April 9-13,1997