Identification and characterization of plant transporters using heterologous expression systems

Journal of Experimental Botany

Volumn 50, Issue SPEC. ISS., 1999, Pages 1073-1087

  Dreyer, Ingo ^a   Horeau, Christèle ^a   Lemaillet, Guy ^a   Zimmermann, Sabine ^b   Bush, Daniel R ^c   Rodríguez Navarro, Alonso ^d   Schachtman, Daniel P ^e   Spalding, Edgar P ^f   Sentenac, Hervé ^a   Gaber, Richard F ^g  

^a CNRS   (France)

^b MAX PLANCK INSTITUTE OF MOLECULAR PLANT PHYSIOLOGY   (Germany)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d Instituto de Biotecnología   (Spain)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f UNIVERSITY OF WISCONSIN MADISON   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cloning strategies; Heterologous expression systems; Membrane transporters; Transport processes; Transport proteins

Indexed keywords

MOLECULAR AND CELLULAR STRUCTURE; MUTATIONAL ANALYSIS;

EMBRYOPHYTA;

EID: 0032970626     PISSN: 00220957     EISSN: None     Source Type: Journal    
DOI: 10.1093/jxb/50.special_issue.1073     Document Type: Conference Paper

References (148)

1. Anderson JA, Huprikar SS, Kochian LV, Lucas WJ, Gaber RF. 1992. Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences, USA 89, 3736-3740.
2. + channels in Saccharomyces cerevisiae: strategies for molecular analysis of structure and function. Symposium of the Society for Experimental Biology 48, 85-97.
3. +/hexose cotransporter from Chlorella in Xenopus oocytes and its characterization with respect to sugar specificity, pH and membrane potential. Journal of Plant Physiology 141, 293-297.
4. ATP channels. Science 282, 1141-1144.
5. + channel KAT1. Proceedings of the National Academy of Sciences, USA 93, 8123-8128.
6. + channel gene in a plant cell model. The Plant Journal 13, 857-865.
7. Bertl A, Anderson JA, Slayman CL, Sentenac H, Gaber RF. 1994. Inward and outward rectifying potassium currents in Saccharomyces cerevisiae mediated by endogenous and heterologously expressed ion channels. Folia Microbiologia (Praha) 39, 507-509.
8. + channel from Arabidopsis thaliana, and comparison with endogeneous yeast channels and carriers. Proceedings of the National Academy of Sciences, USA 92, 2701-2705.
9. Bertl A, Reid JD, Sentenac H, Slayman CL. 1997. Functional expression of plant inward-rectifier channels expressed in yeast. Journal of Experimental Botany 48, 405-413.
10. Boorer KJ, Forde BG, Leigh RA, Miller AJ. 1992. Functional expression of a plant plasma membrane transporter in Xenopus oocytes. FEBS Letters 302, 166-168.
11. +/amino acid transporter from Arabidopsis thaliana. Journal of Biological Chemistry 271, 2213-2220.
12. +/sucrose cotransporter StSUT1, Journal of Biological Chemistry 271, 25139-25144.
13. +/amino acid transporter AAP5. Journal of Biological Chemistry 272, 13040-13046.
14. +-translocating ATPases. Biochemical and Biophysical Research Communications 162, 567-574.
15. + channels and KAT1 and KST1 alpha-subunit homomers of guard cells. Planta 207, 370-376.
16. Bush DR. 1993a. Proton-coupled sugar and amino acid transporters in plants. Annual Review of Plant Physiology and Plant Molecular Biology 44, 513-542.
17. Bush DR. 19936. Inhibitors of the proton-sucrose symport. Archives of Biochemistry and Biophysics 307, 355-360.
18. Cao Y, Anderova M, Crawford NM, Schroeder JI. 1992. Expression of an outward-rectifying potassium channel from maize mRNA and complementary RNA in Xenopus oocytes. The Plant Cell 4, 961-969.
19. + channel KAT1 confer inward-rectification property of plant-animal chimeric channels. Journal of Biological Chemistry 270, 17697-17701.
20. Cao Y, Ward JM, Kelly WB, Ichida AM, Gaber RF, Anderson JA, Uozumi N, Schroeder JI, Crawford NM. 19956. Multiple genes, tissue specificity, and expression-dependent modulation contribute to the functional diversity of potassium channels in Arabidopsis thaliana. Plant Physiology 109, 1093-1106.
21. + symporter. Journal of Biological Chemistry 269, 3498-3502.
22. +-ATPaSe involves phosphorylation during intracellular transport. Journal of Cell Biology 115, 289-295.
23. Chang HC, Bush DR. 1997. Topology of NAT2, a prototypical example of a new family of amino acid transporters. Journal of Biological Chemistry 272, 30552-30557.
24. + channels: structure, activity and function. Biochemical Society Transactions 24, 964-971.
25. Ciorba MA, Heinemann SH, Weissbach H, Brot N, Hoshi T. 1997. Modulation of potassium channel function by methionine oxidation and reduction. Proceedings of the National Academy of Sciences, USA 94, 9932-9937.
26. Clemens S, Antosiewicz DM, Ward JM, Schachtman DP, Schroeder JI. 1998. The plant cDNA LCT1 mediates the uptake of calcium and cadmium in yeast. Proceedings of the National Academy of Sciences, USA 95, 12043-12048.
27. Crestfield AM, Stein WH, Moore S. 1963. Alkylation and identification of the histidine residues at the active site of ribonuclease. Journal of Biological Chemistry 238, 2413-2419.
28. 2+ dependency. EMBO Journal 16, 2565-2575.
29. Daniels MJ, Mirkov TE, Chrispeels MJ. 1994. The plasma membrane of Arabidopsis thaliana contains a mercury-insensitive aquaporin that is a homolog of the tonoplast water channel protein TIP. Plant Physiology 106, 1325-1333.
30. Daniels MJ, Chaumont F, Mirkov TE, Chrispeels MJ. 1996. Characterization of a new vacuolar membrane aquaporin sensitive to mercury at a unique site. The Plant Cell 8, 587-599.
31. Daram P, Urbach S, Gaymard F, Sentenac H, Cherel I. 1997. Tetramerization of the AKT1 plant potassium channel involves its C-terminal cytoplasmic domain. EMBO Journal 16, 3455-3463.
32. + transporter. FEBS Letters 432, 31-36.
33. Dietrich P, Dreyer I, Wiesner P, Hedrich R. 1998. Cation sensitivity and kinetics of guard-cell potassium channels differ among species. Planta 205, 277-287.
34. + conduction and selectivity. Science 280, 69-77.
35. + channel alpha-subunits assemble indiscriminately. Biophysical Journal 72, 2143-2150.
36. in channel KAT1. FEBS Letters 430, 370-376.
37. + channels in open, closed, and inactivated conformations. Journal of Structural Biology 121, 263-284.
38. Eide D, Broderius M, Fett J, Guerinot ML. 1996. A novel iron-regulated metal transporter from plants identified by functional expression in yeast. Proceedings of the National Academy of Sciences, USA 93, 5624-5628.
39. Ehrhardt T, Zimmermann S, Müller-Röber B. 1997. Association of plant K channels is mediated by conserved C-termini and does not affect subunit assembly. FEBS Letters 409, 166-170.
40. Eng BH, Guerinot ML, Eide D, Saier Jr MH. 1998. Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins. Journal of Membrane Biology 166, 1-7.
41. + channel beta subunit. Plant Molecular Biology 37, 597-606.
42. Fields S, Song O. 1989. A novel genetic system to detect protein-protein interactions. Nature 340, 245-246.
43. Fox TC, Guerinot ML. 1998. Molecular biology of cation transport in plants. Annual Reviews of Plant Physiology and Plant Molecular Biology 49, 669-696.
44. Frommer WB, Hummel S, Riesmeier JW. 1993. Expression cloning in yeast of a cDNA encoding a broad specificity amino acid permease from Arabidopsis thaliana. Proceedings of the National Academy of Sciences, USA 90, 5944-5948.
45. Frommer WB, Ninnemann O. 1995. Heterologous expression of genes in bacteria, fungal, animal, and plant cells. Annual Review of Plant Physiology and Plant Molecular Biology 46, 419-444.
46. + transporter from Arabidopsis. The Plant Cell 10, 63-73.
47. + channel from Arabidopsis thaliana. Journal of Biological Chemistry 271, 22863-22870.
48. + release into the xylem sap. Cell 94, 647-655.
49. Gluzman Y. 1981. SV40-transformed simian cells support the replication of early SV40 mutants. Cell 23, 175-182.
50. Grotz N, Fox T, Connolly E, Park W, Guerinot ML, Eide D. 1998. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proceedings of the National Academy of Sciences, USA 95, 7220-7224.
51. Gurdon JB, Lane CD, Woodland HR, Marbaix G. 1971. Use of frog eggs and oocytes for the study of messenger RNA and its translation in living cells. Nature 233, 177-182.
52. +-ATPase) of Arabidopsis thaliana. Proceedings of the National Academy of Sciences, USA 86, 1234-1238.
53. Hechenberger M, Schwappach B, Fischer WN, Frommer WB, Jentsch TJ, Steinmeyer K. 1996. A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. Journal of Biological Chemistry 271, 33632-33638.
54. Hedrich R, Schroeder JI. 1989. The physiology of ion channels and electrogenic pumps in higher plants. Annual Review of Plant Physiology and Plant Molecular Biology 40, 539-569.
55. Hedrich R, Moran O, Conti F, Busch H, Becker D, Gambale F, Dreyer I, Kuch A, Neuwinger K, Palme K. 1995. Inward rectifier potassium channels in plants differ from their animal counterparts in response to voltage and channel modulators. European Biophysics Journal 24, 107-115.
56. + channel signature sequence. Biophysical Journal 66, 1061-1067.
57. Hirsch RE, Lewis BD, Spalding EP, Sussmann MR. 1998 A role for the AKT1 potassium channel in plant nutrition. Science 280, 918-921.
58. 2+ antiporter from Arabidopsis. Proceedings of the National Academy of Sciences, USA 93, 8782-8786.
59. + channel (Kv1.5) by polyunsaturated fatty acids. Proceedings of the National Academy of Sciences, USA 91, 1937-1941.
60. Hoshi T. 1995. Regulation of voltage dependence of the KAT1 channel by intracellular factors. Journal of General Physiology 105, 309-328.
61. + uptake channels. Proceedings of the National Academy of Sciences, USA 94, 4806-4810.
62. + uptake channels. Journal of Experimental Botany 48, 415-420.
63. Hsu LC, Chiou TJ, Chen L, Bush DR. 1993. Cloning a plant amino acid transporter by functional complementation of a yeast amino acid transport mutant. Proceedings of the National Academy of Sciences, USA 90, 7441-7445.
64. + channel KAT1. Journal of Membrane Biology 151, 53-62.
65. +-resistant, light-induced stomatal opening in transgenic Arabidopsis. The Plant Cell 9, 1843-1857.
66. Jan LY, Jan YN. 1997. Cloned potassium channels from eukaryotes and prokaryotes. Annual Review of Neuroscience 20,91-123.
67. Jentsch TJ, Steinmeyer K, Schwarz G. 1990. Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature 348, 510-514.
68. Johansson I, Karlsson M, Shukla VK, Chrispeels MJ, Larsson C, Kjellbom P. 1998. Water transport activity of the plasma membrane aquaporin PM28A is regulated by phosphorylation. The Plant Cell 10, 451-459.
69. Kamb A, Iverson LE, Tanouye MA. 1987. Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Cell 50, 405-413.
70. Kammerloher W, Fischer U, Piechottka GP, Schaffner AR. 1994. Water channels in the plant plasma membrane cloned by immunoselection from a mammalian expression system. The Plant Journal 6, 187-199.
71. Kampfenkel K, Kushnir S, Babiychuk E, Inze D, Van Montagu M. 1995. Molecular characterization of a putative Arabidopsis thaliana copper transporter and its yeast homologue. Journal of Biological Chemistry 270, 28479-28486.
72. + channels. FEBS Letters 378, 19-26.
73. Kim EJ, Kwak JM, Uozumi N, Schroeder JI. 1998. AtKUP1: an Arabidopsis gene encoding high-affinity potassium transport activity. The Plant Cell 10, 51-62.
74. + transporters in Saccharomyces cerevisiae. Molecular and Cellular Biology 11, 4266-4273.
75. + transport cDNAs. Plant and Soil 155/156, 115-118.
76. Köhler C, Neuhaus G. 1998. Cloning and partial characterization of two putative cyclic nucleotide-regulated ion channels from Arabidopsis thaliana, designated CNGC1 and CNGC2. Plant Physiology 116, 1604.
77. Kristoffersen P, Teichmann T, Stracke R, Palme K. 1996. Signal sequence trap to clone cDNAs encoding secreted or membrane-associated plant proteins. Analytical Biochemistry 243, 127-132.
78. Kühlbrandt W, Wang DN. 1991. Three-dimensional structure of plant light-harvesting complex determined by electron crystallography. Nature 350, 130-134.
79. Kwart M, Hirner B, Hummel S, Frommer WB. 1993. Differential expression of two related amino acid transporters with differing substrate specificity in Arabidopsis thaliana. The Plant Journal 4, 993-1002.
80. Lacombe B, Thibaud JB. 1998. Evidence for a multi-ion pore behavior in the plant potassium channel KAT1. Journal of Membrane Biology 166, 91-100.
81. Lam HM, Chiu J, Hsieh MH, Meisel L, Oliveira IC, Shin M, Coruzzi G. 1998. Glutamate-receptor genes in plants. Nature 396, 125-126.
82. + transport defective yeast and distribution of HBP1, a new putative HMG transcriptional regulator. Nucleic Adds Research 22, 3685-3688.
83. Li J, Lee YR, Assmann SM. 1998. Guard cells possess a calcium-dependent protein kinase that phosphorylates the KAT1 potassium channel. Plant Physiology 116, 785-795.
84. Logan H, Basset M, Véry AA, Sentenac H. 1997. Plasma membrane transport systems in higher plants: from black boxes to molecular physiology. Physiologia Plantarum 100, 1-15.
85. Lu JM, Bush DR. 1998. His-65 in the proton-sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases transport activity. Proceedings of the National Academy of Sciences, USA 95, 9025-9030.
86. Lurin C, Geelen D, Barbier-Brygoo H, Guern J, Maurel C. 1996. Cloning and functional expression of a plant voltage-dependent chloride channel. The Plant Cell 8, 701-711.
87. Madrid R, Gomez MJ, Ramos J, Rodriguez-Navarro A. 1998. Ectopic potassium uptake in trk1 trk2 mutants of Saccharomyces cerevisiae correlates with a highly hyperpolarized membrane potential. Journal of Biological Chemistry 273, 14838-14844.
88. Manoil C, Beckwith J. 1986. A genetic approach to analysing membrane protein topology. Science 233, 1403-1408.
89. + channel KAT1 in insect cells. FEBS Letters 380, 229-232.
90. + channel KAT1 depend on the N and C termini. Proceedings of the National Academy of Sciences, USA 94, 3448-3453.
91. Marten I, Hoshi T. 1998. The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field. Biophysical Journal 74, 2953-2962.
92. Maurel C, Reizer J, Schroeder JI, Chrispeels MJ. 1993. The vacuolar membrane protein gamma-TIP creates water specific channels in Xenopus oocytes. EMBO Journal 12, 2241-2247.
93. Maurel C, Kado RT, Guern J, Chrispeels MJ. 1995. Phosphorylation regulates the water channel activity of the seed-specific aquaporin alpha-TIP. EMBO Journal 14, 3028-3035.
94. Maurel C. 1997. Aquaporins and water permeability of plant membranes. Annual Review of Plant Physiology and Plant Molecular Biology 48, 399-429.
95. McCarroll L, King LA. 1997. Stable insect cell cultures for recombinant protein production. Current Opinion in Biotechnology 8, 590-594.
96. Methfessel C, Witzemann V, Takahashi T, Mishina M, Numa S, Sakmann B. 1986. Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels. Pflugers Archiv European Journal of Physiology 407, 577-588.
97. 4 currents through KAT1 channel differently: evidence for ion interaction in channel permeation. Journal of Membrane Biology 163, 25-35.
98. Muchhal US, Pardo JM, Raghothama KG. 1996. Phosphate transporters from the higher plant Ambidopsis thaliana. Proceedings of the National Academy of Sciences, USA 93, 10519-10523.
99. + channel expressed in potato guard cells. EMBO Journal 14, 2409-2416.
100. Nakamura RL, McKendree Jr WL, Hirsch RE, Sedbrook JC, Gaber RF, Sussman MR. 1995. Expression of an Arabidopsis potassium channel gene in guard cells. Plant Physiology 109, 371-374.
101. + channel pore. Journal of Biological Chemistry 272, 1011-1018.
102. Niethammer M, Sheng M. 1998. Identification of ion channel-associated proteins using yeast two-hybrid system. Methods in Enzymology 293, 104-122.
103. 4 transporter from plants. EMBO Journal 13, 3464-3471.
104. +-ATPase isoforms expressed in yeast. Journal of Biological Chemistry 269, 3027-3033.
105. +-ATPase from the plant Arabidopsis thaliana. Journal of Biological Chemistry 264, 8557-8562.
106. Possee RD. 1997. Baculoviruses as expression vectors. Current Opinion in Biotechnology 8, 569-572.
107. + transporters from Arabidopsis that are conserved across phyla. FEBS Letters 415, 206-211.
108. Ramos J, Contreras P, Rodriguez-Navarro A. 1985. A potassium transport mutant of Saccharomyces cerevisiae. Archives of Microbiology 143, 88-93.
109. +-ATPase: yeast as a model system for solute transport across the plant plasma membrane. The Plant Cell 7, 1655-1666.
110. Rentsch D, Boorer KJ, Frommer W. 1997. Structure and function of plasma membrane amino acid, oligopeptide and sucrose transporters from higher plants. Journal of Membrane Biology 162, 177-190.
111. Riesmeier JW, Willmitzer L, Frommer WB. 1992. Isolation and characterization of a sucrose carrier cDNA from spinach by functional expression in yeast. EMBO Journal 11, 4705-4713.
112. Riesmeier JW, Hirner B, Frommer WB. 1993. Potato sucrose transporter expression in minor veins indicates a role in phloem loading. The Plant Cell 5, 1591-1598.
113. + channel ionic selectivity investigated by expression in yeast of randomly mutated channels. Physiologia Plantarum 105, 459-468.
114. Rubio F, Gassmann W, Schroeder JI. 1995. Sodium-driven potassium uptake by the plant potassium transporter HKT1 and mutations conferring salt tolerance. Science 270, 1660-1663.
115. Ruppersberg JP, Stocker M, Pongs O, Heinemann SH, Frank R, Koenen M. 1991. Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature 352, 711-714.
116. Santa-Maria GE, Rubio F, Dubcovsky J, Rodriguez-Navarro A. 1997. The HAK1 gene of barley is a member of a large gene family and encodes a high-affinity potassium transporter. The Plant Cell 9, 2281-2289.
117. +-cotransporter. FEBS Letters 259, 43-46.
118. Sauer N, Caspari T, Klebl F, Tanner W. 1990. Functional expression of the Chlorella hexose transporter in Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences, USA 87, 7949-7952.
119. Schachtman DP, Schroeder JI, Lucas WJ, Anderson JA, Gaber RF. 1992. Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA. Science 258, 1654-1658.
120. Schachtman DP, Schroeder JI. 1994. Structure and transport mechanism of a high-affinity potassium uptake transporter from higher plants. Nature 370, 655-658.
121. Schachtman DP, Kumar R, Schroeder JI, Marsh EL. 1997. Molecular and functional characterization of a novel low-affinity cation transporter (LCT1) in higher plants. Proceedings of the National Academy of Sciences, USA 94, 11079-11084.
122. Schroeder JI. 1994. Heterologous expression and functional analysis of higher plant transport proteins in Xenopus oocytes. Methods 6, 70-81.
123. Schuurink RC, Shartzer SF, Fath A, Jones RL. 1998. Characterization of a calmodulin-binding transporter from the plasma membrane of barley aleurone. Proceedings of the National Academy of Sciences, USA 95, 1944-1949.
124. Schwalbe RA, Wang Z, Wible BA, Brown AM. 1995. Potassium channel structure and function as reported by a single glycosylation sequon. Journal of Biological Chemistry 270, 15336-15340.
125. Sentenac H, Bonneaud N, Minet M, Lacroute F, Salmon JM, Gaymard F, Grignon C. 1992. Cloning and expression in yeast of a plant potassium ion transport system. Science 256, 663-665.
126. Shi J, Dixon RA, Gonzales RA, Kjellbom P, Bhattacharyya MK. 1995. Identification of cDNA clones encoding valosin-containing protein and other plant plasma membrane-associated proteins by a general immunoscreening strategy. Proceedings of the National Academy of Sciences, USA 92, 4457-4461.
127. Shyng SL, Nichols CG. 1998. Membrane phospholipid control of nucleotide sensitivity of KATP channels. Science 282, 1138-1141.
128. Smith FW, Ealing PM, Hawkesford MJ, Clarkson DT. 1995. Plant members of a family of sulphate transporters reveal functional subtypes. Proceedings of the National Academy of Sciences, USA 92, 9373-9377.
129. Steiner HY, Song W, Zhang L, Naider F, Becker JM, Stacey G. 1994. An Arabidopsis peptide transporter is a member of a new class of membrane transport proteins. The Plant Cell 6, 1289-1299.
130. Sussman MR. 1994. Molecular analysis of proteins in the plant plasma membrane. Annual Review of Plant Physiology and Plant Molecular Biology 45, 211-234.
131. + channel alpha subunits. The Plant Cell 8, 1545-1553.
132. Tanner W, Caspari T. 1996. Membrane transport carriers. Annual Review of Plant Physiology and Plant Molecular Biology 47, 595-626.
133. Theodoulou FL, Miller AJ. 1995. Xenopus oocytes as a heterologous expression system for plant proteins. Molecular Biotechnology 3, 101-115.
134. Tsay YF, Schroeder JI, Feldmann KA, Crawford NM. 1993. The herbicide sensitivity gene CHL1 of Arabidopsis encodes a nitrate-inducible nitrate transporter. Cell 72, 705-713.
135. Tyerman SD, Schachtman DP. 1992. The role of ion channels in plant nutrition and prospects for their genetic manipulation. Plant and Soil 146, 137-144.
136. Tzounopoulos T, Maylie J, Adelman JP. 1995. Induction of endogenous channels by high levels of heterologous membrane proteins in Xenopus oocytes. Biophysical Journal 69, 904-908.
137. Uozumi N, Gassmann W, Cao Y, Schroeder JI. 1995. Identification of strong modifications in cation selectivity in an Arabidopsis inward rectifying potassium channel by mutant selection in yeast. Journal of Biological Chemistry 270, 24276-24281.
138. Uozumi N, Nakamura T, Schroeder JI, Muto S. 1998. Determination of transmembrane topology of an inward-rectifying potassium channel from Arabidopsis thaliana based on functional expression in Escherichia coli. Proceedings of the National Academy of Sciences, USA 95, 9773-9778.
139. + channel. Pflügers Archive 428, 422-424.
140. + channel in Xenopus oocytes: analysis of macroscopic currents. The Plant Journal 7, 321-332.
141. +-ATPase in yeast endoplasmic reticulum. Journal of Biological Chemistry 267, 12341-12349.
142. Westhead EW. 1965. Photooxidation with rose bengal of a critical histidine residue in yeast enolase. Biochemistry 4, 2139-2144.
143. + cotransporter randomly generated by PCR. Proceedings of the National Academy of Sciences, USA 91, 10163-10167.
144. + symporters. FEBS Letters 381, 127-130.
145. + symporters by mutations and construction of chimeras. Journal of Biological Chemistry 273, 11456-11462.
146. Zei PC, Aldrich RW. 1998. Voltage-dependent gating of single wild-type and S4 mutant KAT1 inward rectifier potassium channels. Journal of General Physiology 112, 679-713.
147. Zeilinger C. 1994. Isolation of a potassium-selective ion channel from the plasma membrane of the broad bean Vicia faba L. FEBS Letters 348, 278-282.
148. Zimmermann S, Talke I, Ehrhardt T, Nast G, Müller-Röber B. 1998. Characterization of SKT1, an inwardly rectifying potassium channel from potato, by heterologous expression in insect cells. Plant Physiology 116, 879-890.