Oxidative stress response induced in rat primary hepatocyte monolayers by mechanical removal of adherent cells

Cell and Tissue Research

Volumn 295, Issue 2, 1999, Pages 363-367

  Pillar, Timothy M ^a   Seitz, Hans Joachim ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Haem oxygenase; Manganese superoxide dismutase; Oxidative stress; Primary hepatocytes; Rat (Wistar)

Indexed keywords

HEME OXYGENASE; MANGANESE SUPEROXIDE DISMUTASE;

ADHERENT CELL; ANIMAL CELL; ARTICLE; LIVER CELL; LIVER CELL CULTURE; MONOLAYER CULTURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; CELL ADHESION; CELLS, CULTURED; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE (DECYCLIZING); LIVER; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 0032970429     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410051243     Document Type: Article

References (21)

1. Abraham NG, Drummond GS, Lutton JD, Kappas A (1996) The biological significance and physiological role of heme oxygenase. Cell Physiol Biochem 6:129-168
2. Baeuerle PA, Rupee RA, Pahl HL (1996) Reactive oxygen intemediates as second messengers of a general pathogen response. Pathol Biol 44:29-35
3. Berry MN (1975) Use of isolated liver cells and kidney tubules in metabolic studies. North Holland, Amsterdam
4. Brown T, Mackey K (1995) Analysis of RNA by Northern and slot blotting. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (eds) Current protocols in molecular biology. Wiley, New York, chap 4.9, pp 2-8
5. Camhi SL, Alam J, Wiegand GW, Chin BY, Choi AM (1998) Transcriptional activation of the HO-1 gene by lipopolysaccharide is mediated by 5' distal enhancers: role of reactive oxygen intermediates and AP-1. Am J Resp Cell Mol Biol 18:226-234
6. Clayton DF, Darnell JE (1983) Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol 3:1552-1561
7. Elbirt KK, Witmarsh AJ, Davis RJ, Bonkovsky HL (1998) Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen activated protein kinases. J Biol Chem 273:8922-8926
8. Gerlach JC (1997) Long-term liver cell cultures in bioreactors and possible application for liver support. Cell Biol Toxicol 13:349-355
9. Goda N, Suzuki K, Naito M, Takeoka S, Tschuchida E, Ishimura Y, Tamatani T (1997) Distribution of heme oxygenease isoforms in rat liver. J Clin Invest 101:604-612
10. Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R (1997) Cloning and initial characterization of human and mouse Spot 14 genes. FEBS Lett 401:38-42
11. Hartsfield CL, Alam J, Cook JL, Choi AM (1997) Regulation of heme oxygenase-1 gene expression in vascular smooth muscle by nitric oxide. Am J Physiol 273:L980-L988
12. Lavrovsky Y, Schwartzman ML, Levere RD, Kappas A, Abraham NG (1994) Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci USA 91:5987-5991
13. Lavrovsky Y, Drummond GS, Abraham NG (1996) Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements. Biochem Biophys Res Commun 218:759-765
14. Padgham CRW, Boyle CC, Wang X-J,Raleigh SM, Wright MC, Paine AJ (1993) Alteration of transcription factor mRNAs during the isolation and culture of rat hepatocytes suggests the activation of a proliferative mode underlies their de-differentiation. Biochem Biophys Res Commun 197:599-605
15. Poss KD, Tonegawa S (1997) Reduced stress defense in heme oxygenase-1 deficient cells. Proc Natl Acad Sci USA 94:10925-10930
16. Riordan S, Williams R (1997) Bioartificial liver support: developments in hepatocyte culture and bioreactor design. Br Med Bull 53:730-744
17. Schulze-Osthoff K, Beyaert R, Vandevoorde V, Haegeman G, Fiers W (1993) Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J 12:3095-3104
18. Shibahara S, Sato M, Muller RM, Yoshida T (1989) Structural organization of the human heme oxygenase gene and the function of its promoter. Eur J Biochem 179:557-563
19. Topper JN, Cai J, Falb D, Gimbrone MA (1996) Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli; cyclooxygenase-2, manganese Superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93:10417-10422
20. Wagner CT, Durante W, Christodoulides N, Heliums JD, Schafer AI (1997) Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells. J Clin Invest 589-596
21. Yamaguchi T, Terakado M, Horio F, Aoki K, Tanaka M, Nakajima H (1996) Role of bilirubin as an antioxidant in an ischemia-reperfusion of rat liver and induction of heme oxygenase. Biochem Biophys Res Commun 223: 129-135