메뉴 건너뛰기




Volumn 22, Issue 1, 1999, Pages 23-28

Effects of the combined administration of hexarelin, a synthetic peptidyl GH secretagogue, and hCRH on ACTH, cortisol and GH secretion in patients with Cushing's disease

Author keywords

ACTH; Cortisol; Cushing's disease; GH; hCRH; Hexarelin

Indexed keywords

ARGIPRESSIN; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HEXARELIN; HYDROCORTISONE;

EID: 0032969045     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03345474     Document Type: Article
Times cited : (17)

References (32)
  • 5
    • 0028903627 scopus 로고
    • Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release
    • Korbonits M., Grossman A.B. Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release. Trends Endocrinol. Metab., 6: 43, 1995.
    • (1995) Trends Endocrinol. Metab. , vol.6 , pp. 43
    • Korbonits, M.1    Grossman, A.B.2
  • 6
    • 0024396484 scopus 로고
    • Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites
    • Codd E.E., Shu A.Y.L, Walker R.F. Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites. Neuropharmacology, 28: 1139, 1989.
    • (1989) Neuropharmacology , vol.28 , pp. 1139
    • Codd, E.E.1    Shu, A.Y.L.2    Walker, R.F.3
  • 11
    • 0026607276 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors
    • Goth M.I., Lyons C.E., Canny B.Y., Thorner M.O. Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology 130: 939, 1992.
    • (1992) Endocrinology , vol.130 , pp. 939
    • Goth, M.I.1    Lyons, C.E.2    Canny, B.Y.3    Thorner, M.O.4
  • 12
    • 0028929627 scopus 로고
    • Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action
    • Fairhall K.M., Mynett A., Robinson I.C.A.F. Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action. J. Endocrinol. 144: 555, 1995.
    • (1995) J. Endocrinol. , vol.144 , pp. 555
    • Fairhall, K.M.1    Mynett, A.2    Robinson, I.C.A.F.3
  • 13
    • 0031057817 scopus 로고    scopus 로고
    • Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurons in the rat arcuate nucleus following systemic injection of the GH secretagogue, GH-releasing peptide-6
    • Dickson S.L., Luckman S.M. Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurons in the rat arcuate nucleus following systemic injection of the GH secretagogue, GH-releasing peptide-6. Endocrinology 138: 771, 1997.
    • (1997) Endocrinology , vol.138 , pp. 771
    • Dickson, S.L.1    Luckman, S.M.2
  • 14
    • 0028968462 scopus 로고
    • Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: Evidence that GHRP-6 main action is exerted at the hypothalamic level
    • Popovic V., Damjanovic S., Micic D., Djurovic M., Dieguez C., Casanueva F.F. Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. J. Clin. Endocrinol. Metab. 80: 942, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 942
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3    Djurovic, M.4    Dieguez, C.5    Casanueva, F.F.6
  • 15
    • 0028807113 scopus 로고
    • Absence of growth hormone (GH) secretion after the administration of either GH releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection
    • Pombo M., Barreiro J., Penalva A., Peino R., Dieguez C., Casanueva F.F. Absence of growth hormone (GH) secretion after the administration of either GH releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection. J. Clin. Endocrinol. Metab. 80: 3180, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3180
    • Pombo, M.1    Barreiro, J.2    Penalva, A.3    Peino, R.4    Dieguez, C.5    Casanueva, F.F.6
  • 18
    • 0031439845 scopus 로고    scopus 로고
    • Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors
    • De Keyzer Y., Lenne F., Bertagna X. Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors. Eur. J. Endocrinol. 737: 715, 1997.
    • (1997) Eur. J. Endocrinol. , vol.737 , pp. 715
    • De Keyzer, Y.1    Lenne, F.2    Bertagna, X.3
  • 20
    • 0030909925 scopus 로고    scopus 로고
    • Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats
    • Thomas G.B., Fairhall K.M., Robinson I.C.A.F. Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats. Endocrinology 138: 1585, 1997.
    • (1997) Endocrinology , vol.138 , pp. 1585
    • Thomas, G.B.1    Fairhall, K.M.2    Robinson, I.C.A.F.3
  • 21
    • 0029097574 scopus 로고
    • The effect of an opiate antagonist on the hormonal changes induced by hexarelin
    • Korbonits M., Trainer P.J., Besser G.M. The effect of an opiate antagonist on the hormonal changes induced by hexarelin. Clin. Endocrinol. (Oxf.) 43: 365, 1995.
    • (1995) Clin. Endocrinol. (Oxf.) , vol.43 , pp. 365
    • Korbonits, M.1    Trainer, P.J.2    Besser, G.M.3
  • 22
    • 0030771596 scopus 로고    scopus 로고
    • Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-reieasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans
    • Arvat E., Maccagno B., Ramunni J., Di Vito L., Broglio F., Deghenghi R., Camanni F., Ghigo E. Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-reieasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans. Neuroendocrinology 66: 432, 1997.
    • (1997) Neuroendocrinology , vol.66 , pp. 432
    • Arvat, E.1    Maccagno, B.2    Ramunni, J.3    Di Vito, L.4    Broglio, F.5    Deghenghi, R.6    Camanni, F.7    Ghigo, E.8
  • 23
    • 0030743911 scopus 로고    scopus 로고
    • Adrenocorticotropin-and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome
    • Ghigo E., Arvat E., Ramunni J., Colao A., Gianotti L., Deghenghi R., Lombardi G., Camanni F. Adrenocorticotropin-and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome. J. Clin. Endocrinol. Metab. 82: 2439, 1997.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2439
    • Ghigo, E.1    Arvat, E.2    Ramunni, J.3    Colao, A.4    Gianotti, L.5    Deghenghi, R.6    Lombardi, G.7    Camanni, F.8
  • 24
    • 0026693320 scopus 로고
    • Corticotropin-releasing hormone in humans
    • Orth D.N. Corticotropin-releasing hormone in humans. Endocr. Rev. 73: 164, 1992.
    • (1992) Endocr. Rev. , vol.73 , pp. 164
    • Orth, D.N.1
  • 26
    • 0027944106 scopus 로고
    • Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles
    • Jacks T., Hickey G., Judith F., Taylor J., Chen H., Krupa D., Feeney W., Schoen W., Fisher M., Wyratt M., Smith R. Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. J. Endocrinol. 143: 399, 1994.
    • (1994) J. Endocrinol. , vol.143 , pp. 399
    • Jacks, T.1    Hickey, G.2    Judith, F.3    Taylor, J.4    Chen, H.5    Krupa, D.6    Feeney, W.7    Schoen, W.8    Fisher, M.9    Wyratt, M.10    Smith, R.11
  • 27
    • 0031961561 scopus 로고    scopus 로고
    • Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of Hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans
    • Arvat E., Maccagno B., Ramunni J., Di Vito L., Gianotti L., Broglio F., Benso A., Deghenghi R., Camanni F., Ghigo E. Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of Hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans. Neuroendocrinology, 67: 310, 1998.
    • (1998) Neuroendocrinology , vol.67 , pp. 310
    • Arvat, E.1    Maccagno, B.2    Ramunni, J.3    Di Vito, L.4    Gianotti, L.5    Broglio, F.6    Benso, A.7    Deghenghi, R.8    Camanni, F.9    Ghigo, E.10
  • 31
    • 0345262973 scopus 로고    scopus 로고
    • Influence of galanin and serotonin on the GH, PRL, ACTH and cortisol response to Hexarelin, a synthetic GHRP, in humans
    • Abstract
    • Di Vito L., Arvat E., Gianotti L., Broglio F., Sortino G., Lanfranco F., Deghenghi R., Ghigo E. Influence of galanin and serotonin on the GH, PRL, ACTH and cortisol response to Hexarelin, a synthetic GHRP, in humans. Ann. Endocr, 58: 86 (Abstract) P1-6, 1997.
    • (1997) Ann. Endocr , vol.58 , Issue.86
    • Di Vito, L.1    Arvat, E.2    Gianotti, L.3    Broglio, F.4    Sortino, G.5    Lanfranco, F.6    Deghenghi, R.7    Ghigo, E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.