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Viraben R, Aquilina C Indinavir-associated lipodystrophy. AIDS 1998; 12: F37-• F39. This article describes the loss of subcutaneous fat tissue in a group of patients on HAART including indinavir from the dermatologist' point of view. Fat wasting appeared after a median follow-up of 8.5 months (range: 2-12) Patients also showed hyperinsulinaemia
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Carr A, Samaras K, Burton S, Law M, Freund J, Chisholm DJ, Cooper DA. A •• syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998; 12: F51-F58. This may be the most comprehensive study to date on the metabolic abnormalities and lipodystrophy associated with protease inhibitor therapy. It is a cross-sectional study, but provides insight into the prevalence of diabetes mellitus and lipodystrophy with different protease inhibitor regimens.
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Flexner C. HIV-protease inhibitors. N Engl J Med 1998; 338: 1281-1292 •• This is the most comprehensive review on protease inhibitors to date. Lipodystrophy in association with protease inhibitors is recognized for the first time in a review on protease inhibitors.
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Stocker DN, Merer PJ, Stoller R, Fattinger KE "Buffalo hump" in HIV-1 • infection. Lancet 1998; 352: 320-321 These authors described anecdotal cases of coronary disease in young adult HIV-1 infected patients who had metabolic abnormalities after starting protease inhibitor therapy. Although these results cannot be generalized at present, serious concern exists that HIV-1 infected patients with metabolic abnormalities may be at a high cardiovascular risk in the near future.
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Henry, K.1
Melroe, H.2
Huebesch, J.3
Hermundson, J.4
Simpson, J.5
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63
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0004803863
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Treatment of dorsocervical fat pads and truncal adiposity with serostim (recombinant human growth hormone) in patients with AIDS maintained on HAART
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Geneva abstract 32164
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Torres R. Treatment of dorsocervical fat pads and truncal adiposity with serostim (recombinant human growth hormone) in patients with AIDS maintained on HAART. 12th World Conference on AIDS, Geneva 1998: abstract 32164.
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(1998)
12th World Conference on AIDS
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Torres, R.1
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