Direct determination of stability of protease inhibitors in plasma by HPLC with automated column-switching

Journal of Pharmaceutical and Biomedical Analysis

Volumn 19, Issue 3-4, 1999, Pages 343-349

  Peng, Sean X ^a   Strojnowski, Michael J ^a   Bornes, David M ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Column switching; Drug stability; MMP inhibitors; RAM column

Indexed keywords

HYDROXYAMINO ACID; METALLOPROTEINASE INHIBITOR; PGE 1132881; PGE 4410186; PGE 9818266; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; AUTOANALYSIS; DEVICE; DRUG BLOOD LEVEL; DRUG STABILITY; EVAPORATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRECIPITATION; PRIORITY JOURNAL;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; EVALUATION STUDIES; HYDROXAMIC ACIDS; MATRIX METALLOPROTEINASES; PROTEASE INHIBITORS; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 0032968630     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(98)00127-7     Document Type: Article

References (16)

1. Hagestam I.H., Pinkerton T.C. Anal. Chem. 57:1985;1757-1763.
2. Pinkerton T.C. J. Chromatogr. 544:1991;13-23.
3. Desilets C.P., Rounds M.A., Regnier F.E. J. Chromatogr. 554:1991;25-39.
4. Boos K.-S., Rudolphi A. LC/GC. 15:1997;602-611.
5. Rudolphi A., Boos K.-S. LC/GC. 15:1997;814-823.
6. Saarinen M.T., Siren H., Riekkola M.-L. J. Chromatogr. B. 664:1995;341-346.
7. Zehender H., Denouel J., Roy M., Saux L.L., Schaub P. J. Chromatogr. B. 664:1995;347-355.
8. Miller-Stein C., Hwang B.Y.-H., Rhodes G.R., Boppana V.K. J. Chromatogr. 631:1993;233-240.
9. Lacroix C., Wojciechowski F., Danger P. J. Chromatogr. 617:1993;285-290.
10. Puhlmann A., Dulffer T., Kobold U. J. Chromatogr. 581:1992;129-133.
11. Ohta T., Niida S., Nakamura H. J. Chromatogr. 675:1996;168-173.
12. Rudolphi A., Vielhauer S., Boos K.-S., Seidel D., Bathge I.-M., Berger H. J. Pharm. Biomed. Anal. 13:1995;615-623.
13. Ruckmick S.C., Hench B.D. J. Chromatogr. 565:1991;277-295.
14. Chu Y.-Q., Wainer I.W. Pharm. Res. 5:1988;680-683.
15. Mathes L.E., Muschik G., Demby L., Polas P., Mellini D.W., Issaq H.J., Sams R. J. Chromatogr. 432:1988;346-351.
16. Pinkerton T.C., Miller T.D., Cook S.E., Perry J.A., Rateike J.D., Szczerba T.J. Biochromatography. 1:1986;96-105.