Optimization of direct pelletization process of a beta- cyclodextrin/microcrystalline cellulose mixture in fluidized bed rotor granulator;Ottimizzazione del processo di pellettizzazione diretta di una miscela β-ciclodestrina/cellulosa microcristallina in rotogranulatore a letto fluido

Bollettino Chimico Farmaceutico

Volumn 138, Issue 3, 1999, Pages 79-85

  Palugan, L ^a   Cerea, M ^a   Vecchio, C ^b   Zema, L ^a   Sangalli, M E ^a   Maroni, A ^a   Giordano, F ^c   Gazzaniga, A ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Pharmaceutical Technologies R and D   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CYCLODEXTRIN; MICROCRYSTALLINE CELLULOSE;

CONFERENCE PAPER; DRUG GRANULATION; FLUIDIZED BED; PELLET EXTRUSION;

EID: 0032967766     PISSN: 00066648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (4)

1. M.E. Sangalli, C. Vecchio, L. Zema, L. Rampoldi, F. Giordano, A. Gazzaniga, Preparation of pellets from betacyclodextrin/drug mixtures by extruision/spheronisation processi Proc. 2nd World Meeting APGI/APV, pages 443-444, (1998).
2. A. Gazzaniga, M.E. Sangalli, G. Bruni, L. Zema, C. Vecchio, F. Giordano, The use of B-Cyclodextrins as a Pelletization Agent in the Extrusion/Spheronization Process, Drug Dev. Ind. Pharm. 24(9), 71-75 (1998).
3. C. Vecchio, C. Lombardi, M. Pedrani, M. Battig, A. Gazzaniga, Aspetti techologici dei processo di pellettizzazione mediante rotogranulatore a letto fluido, Boll. Chim. Farmaceutico, 135, 150-154 (1996).
4. P.Wehrie, D.Korner, S.Benita, Sequential Statistical Optimization of a Positively-Charged Submicron Emulsion of Miconazole, Pharm. Dev. Techn., 1(1), 97-11 (1996).