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Volumn 21, Issue 5, 1999, Pages 829-840

Pharmacokinetics and pharmacodynamics of clomethiazole after oral and rectal administration in healthy subjects

Author keywords

Clomethiazole; Oral administration; Pharmacodynamics; Pharmacokinetics; Reaction time; Rectal administration; Single dose

Indexed keywords

CLOMETHIAZOLE;

EID: 0032967447     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(99)80005-8     Document Type: Article
Times cited : (8)

References (27)
  • 1
    • 0018168416 scopus 로고
    • Piracetam and chlormethiazole in acute alcohol withdrawal: A controlled clinical trial
    • 1. Dencker SJ, Wilhelmson G, Carlsson E. Piracetam and chlormethiazole in acute alcohol withdrawal: A controlled clinical trial. J Int Med Res. 1978;6:395-400.
    • (1978) J Int Med Res. , vol.6 , pp. 395-400
    • Dencker, S.J.1    Wilhelmson, G.2    Carlsson, E.3
  • 2
    • 0018148218 scopus 로고
    • Kinetics of chlormethiazole in patients with alcohol withdrawal manifestations
    • 2. Jostell KG, Agurell S, Hollister LE, Wermuth BW. Kinetics of chlormethiazole in patients with alcohol withdrawal manifestations. Clin Pharmacol Ther. 1978;23: 181-187.
    • (1978) Clin Pharmacol Ther. , vol.23 , pp. 181-187
    • Jostell, K.G.1    Agurell, S.2    Hollister, L.E.3    Wermuth, B.W.4
  • 3
    • 0025752258 scopus 로고
    • Chlormethiazole: Current status in the treatment of the acute ethanol withdrawal syndrome
    • 3. Majumdar SK. Chlormethiazole: Current status in the treatment of the acute ethanol withdrawal syndrome. Drug Alcohol Depend. 1990;27:201-207.
    • (1990) Drug Alcohol Depend , vol.27 , pp. 201-207
    • Majumdar, S.K.1
  • 4
    • 0001325567 scopus 로고
    • Controlled trial of chlormethiazole in treatment of the alcoholic withdrawal phase
    • 4. Glatt MM, George HR, Frisch EP. Controlled trial of chlormethiazole in treatment of the alcoholic withdrawal phase. BMJ. 1965;2:401-404.
    • (1965) BMJ , vol.2 , pp. 401-404
    • Glatt, M.M.1    George, H.R.2    Frisch, E.P.3
  • 5
    • 84995255608 scopus 로고
    • A comparison of chlormethiazole and thioridazine in agitated confusional states of the elderly
    • 5. Ather SA, Shaw SH, Stoker MJ. A comparison of chlormethiazole and thioridazine in agitated confusional states of the elderly. Acta Psychiatr Scand Suppl. 1986;73(Suppl 329):81-91.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 81-91
    • Ather, S.A.1    Shaw, S.H.2    Stoker, M.J.3
  • 6
    • 0018208668 scopus 로고
    • A controlled trial of chlormethiazole in the management of symptoms of the organic dementias in the elderly
    • 6. Magnus RV. A controlled trial of chlormethiazole in the management of symptoms of the organic dementias in the elderly. Clin Ther. 1978;1:387-396.
    • (1978) Clin Ther. , vol.1 , pp. 387-396
    • Magnus, R.V.1
  • 7
    • 0019133522 scopus 로고
    • Low dose chlormethiazole infusion as a supplement to central neural blockade: Blood concentrations and clinical effects
    • 7. Mather LE, Cousins MJ. Low dose chlormethiazole infusion as a supplement to central neural blockade: Blood concentrations and clinical effects. Anaesth Intensive Care. 1980;8:421-425.
    • (1980) Anaesth Intensive Care , vol.8 , pp. 421-425
    • Mather, L.E.1    Cousins, M.J.2
  • 8
    • 0018088199 scopus 로고
    • Chlormethiazole (Hemineurin) infusion as supplemental sedation during epidural block
    • 8. Schweitzer SA. Chlormethiazole (Hemineurin) infusion as supplemental sedation during epidural block. Anaesth Intensive Care. 1978;6:248-250.
    • (1978) Anaesth Intensive Care , vol.6 , pp. 248-250
    • Schweitzer, S.A.1
  • 9
    • 0022653559 scopus 로고
    • Chlormethiazole in the management of post-craniotomy seizures
    • 9. Gurusinghe NT, Symon L, Jekes LSD, et al. Chlormethiazole in the management of post-craniotomy seizures. Acta Psychiatr Scand Suppl. 1986;73(Suppl 329):189-193.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 189-193
    • Gurusinghe, N.T.1    Symon, L.2    Jekes, L.S.D.3
  • 10
    • 0021119248 scopus 로고
    • Eclampsia and severe cases of pre-eclampsia treated with chlormethiazole (Heminevrin) during a 10 year period
    • 10. Johannesen P. Eclampsia and severe cases of pre-eclampsia treated with chlormethiazole (Heminevrin) during a 10 year period. Scand J Clin Lab Invest Suppl. 1984;169:76-78.
    • (1984) Scand J Clin Lab Invest Suppl. , vol.169 , pp. 76-78
    • Johannesen, P.1
  • 11
    • 0018363849 scopus 로고
    • Chlormethiazol (Distraneurin®) als sedativum bei präeklampsie
    • 11. Berger C. Chlormethiazol (Distraneurin®) als Sedativum bei Präeklampsie. Schweiz Rundsch Med Prax. 1979;68:971-977.
    • (1979) Schweiz Rundsch Med Prax , vol.68 , pp. 971-977
    • Berger, C.1
  • 12
    • 0022628789 scopus 로고
    • A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly
    • 12. Bayer AJ, Bayer EM, Pathy MSJ, Stoker MJ. A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly. Acta Psychiatr Scand Suppl. 1986;73(Suppl 329):104-111.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 104-111
    • Bayer, A.J.1    Bayer, E.M.2    Pathy, M.S.J.3    Stoker, M.J.4
  • 13
    • 0018048281 scopus 로고
    • The hypnotic effect of chlormethiazole during long-term treatment of geriatric patients
    • 13. Dehlin O, Falkheden T, Gatzinska R, Nordqvist P. The hypnotic effect of chlormethiazole during long-term treatment of geriatric patients. Clin Ther. 1978; 2:41-49.
    • (1978) Clin Ther. , vol.2 , pp. 41-49
    • Dehlin, O.1    Falkheden, T.2    Gatzinska, R.3    Nordqvist, P.4
  • 14
    • 0022652146 scopus 로고
    • A double-blind comparison of chlormethiazole and temazepam in elderly patients with sleep disturbances
    • 14. Pathy MSJ, Bayer AJ, Stoker MJ. A double-blind comparison of chlormethiazole and temazepam in elderly patients with sleep disturbances. Acta Psychiatr Scand Suppl. 1986;73(Suppl 329);99-103.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 99-103
    • Pathy, M.S.J.1    Bayer, A.J.2    Stoker, M.J.3
  • 15
    • 0022618993 scopus 로고
    • Circulatory and respiratory effects of chlormethiazole
    • 15. Scott DB. Circulatory and respiratory effects of chlormethiazole. Acta Psychiatr Scand Suppl. 1986;73(Suppl 329):28-31.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 28-31
    • Scott, D.B.1
  • 16
    • 0018787504 scopus 로고
    • Poisoning with chlormethiazole
    • 16. McInnes GT, Young RE, Avery BS. Poisoning with chlormethiazole. BMJ. 1979; 2:1218-1219.
    • (1979) BMJ , vol.2 , pp. 1218-1219
    • McInnes, G.T.1    Young, R.E.2    Avery, B.S.3
  • 17
    • 84995205535 scopus 로고
    • Chlormethiazole in intensive care
    • 17. Scott DB. Chlormethiazole in intensive care. Acta Psychiatr Scand Suppl. 1986; 72(Suppl 329):185-188.
    • (1986) Acta Psychiatr Scand Suppl. , vol.72 , Issue.SUPPL. 329 , pp. 185-188
    • Scott, D.B.1
  • 18
    • 0027109956 scopus 로고
    • Intravenous chlormethiazole
    • 18. Fulton B, Park GR. Intravenous chlormethiazole. Br J Hosp Med. 1992;48:742-747.
    • (1992) Br J Hosp Med. , vol.48 , pp. 742-747
    • Fulton, B.1    Park, G.R.2
  • 19
    • 0025778611 scopus 로고
    • Pharmacokinetics of rectal drug administration. Part I. General considerations and clinical applications of centrally acting drugs
    • 19. van Hoogdalem E, de Boer AG, Breimer DD. Pharmacokinetics of rectal drug administration. Part I. General considerations and clinical applications of centrally acting drugs. Clin Pharmacokinet. 1991;21:11-26.
    • (1991) Clin Pharmacokinet. , vol.21 , pp. 11-26
    • Van Hoogdalem, E.1    De Boer, A.G.2    Breimer, D.D.3
  • 21
    • 0017743032 scopus 로고
    • Plasma levels of chlormethiazole and two metabolites after oral administration to young and aged human subjects
    • 21. Nation RL, Vine J, Triggs EJ, Learoyd B. Plasma levels of chlormethiazole and two metabolites after oral administration to young and aged human subjects. Eur J Clin Pharmacol. 1977;12:137-145.
    • (1977) Eur J Clin Pharmacol. , vol.12 , pp. 137-145
    • Nation, R.L.1    Vine, J.2    Triggs, E.J.3    Learoyd, B.4
  • 22
    • 0019468714 scopus 로고
    • Direct measurement of chlormethiazole extraction by liver, lung and kidney in man
    • 22. Mather LE, Runciman WB, Ilsley AH, et al. Direct measurement of chlormethiazole extraction by liver, lung and kidney in man. Br J Clin Pharmacol. 1981;12: 319-325.
    • (1981) Br J Clin Pharmacol. , vol.12 , pp. 319-325
    • Mather, L.E.1    Runciman, W.B.2    Ilsley, A.H.3
  • 23
    • 0019474283 scopus 로고
    • An integrated study of the pharmacokinetics and pharmacodynamics of chlormethiazole in healthy young volunteers
    • 23. Seow LT, Mather LE, Roberts JG. An integrated study of the pharmacokinetics and pharmacodynamics of chlormethiazole in healthy young volunteers. Eur J Clin Pharmacol. 1981;19:263-269.
    • (1981) Eur J Clin Pharmacol. , vol.19 , pp. 263-269
    • Seow, L.T.1    Mather, L.E.2    Roberts, J.G.3
  • 24
    • 0023510805 scopus 로고
    • A new self adjusting reaction time device (BonnDet) wilh high test-retest reliability
    • 24. Langewitz W, Bieling H, Stephan JA, Otten H. A new self adjusting reaction time device (BonnDet) wilh high test-retest reliability. J Psychophysiol. 1987;1:67-77.
    • (1987) J Psychophysiol. , vol.1 , pp. 67-77
    • Langewitz, W.1    Bieling, H.2    Stephan, J.A.3    Otten, H.4
  • 25
    • 0026049514 scopus 로고
    • A single-dose study of the pharmacodynamic effects of chlormethiazole, temazepam and placebo in elderly parkinsonian patients
    • 25. Tulloch JA, Ashwood TJ, Bateman DN, Woodhouse KW. A single-dose study of the pharmacodynamic effects of chlormethiazole, temazepam and placebo in elderly parkinsonian patients. Age Ageing. 1991; 20:424-429.
    • (1991) Age Ageing , vol.20 , pp. 424-429
    • Tulloch, J.A.1    Ashwood, T.J.2    Bateman, D.N.3    Woodhouse, K.W.4
  • 26
    • 0022627809 scopus 로고
    • The bioavailability and pharmacodynamics of chlormethiazole in healthy young and elderly volunteers: Preliminary findings
    • 26. Jostell KG, Fagan D, Björk M, et al. The bioavailability and pharmacodynamics of chlormethiazole in healthy young and elderly volunteers: Preliminary findings. Acta Psychiatr Scand Suppl. 1986;73 (Suppl 329):32-33.
    • (1986) Acta Psychiatr Scand Suppl. , vol.73 , Issue.SUPPL. 329 , pp. 32-33
    • Jostell, K.G.1    Fagan, D.2    Björk, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.