The novel analgesic compound OT-7100 (5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo [1,5-α] pyrimidine) attenuates mechanical nociceptive responses in animal models of acute and peripheral neuropathic hyperalgesia

Japanese Journal of Pharmacology

Volumn 79, Issue 1, 1999, Pages 65-73

  Yasuda, Tsuneo ^a   Iwamoto, Takeshi ^a   Ohara, Masayuki ^a   Sato, Seiji ^a   Kohri, Hideaki ^a   Noguchi, Koichi ^b   Senba, Emiko ^c  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Analgesic; Chronic neuropathy; Hyperalgesia; OT 7100

Indexed keywords

5 BUTYL 7 (3,4,5 TRIMETHOXYBENZAMIDO)PYRAZOLO[1,5 A]PYRIMIDINE; AMITRIPTYLINE; ANALGESIC AGENT; CLONAZEPAM; INDOMETACIN; PROSTAGLANDIN E2; SUBSTANCE P; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; HYPERALGESIA; MALE; NERVE INJURY; NEUROPATHY; NOCICEPTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PAIN THRESHOLD; PROSTAGLANDIN SYNTHESIS; SCIATIC NERVE; YEAST;

EID: 0032967274     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.79.65     Document Type: Article

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