Utility of microcalorimetry in the characterization of the browning reaction

Journal of Pharmaceutical and Biomedical Analysis

Volumn 20, Issue 1-2, 1999, Pages 385-388

  Vickery, Rodney D ^a   Maurin, Michael B ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Cyclic urea; DMP 450; HIV protease inhibitor; Isothermal microcalorimetry; Lactose

Indexed keywords

LACTOSE; MOZENAVIR; PROTEINASE INHIBITOR;

ARTICLE; CATALYSIS; DRUG DEGRADATION; DRUG DETERMINATION; ENERGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROCALORIMETRY; MOLECULAR INTERACTION; PHYSICAL PHASE; PRIORITY JOURNAL; TEMPERATURE;

AZEPINES; CALORIMETRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEAT; HIV PROTEASE INHIBITORS; LACTOSE; TEMPERATURE; UREA;

EID: 0032967257     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00071-0     Document Type: Article

References (4)

1. M. Angberg, Evaluation of Isothermal Heat-Conduction Microcalorimetry in Pharmaceutical Stability Studies. Doctorial thesis at Uppsala University (1992) 10-25.
2. Hansen L.D., Lewis E.A., Eatough D.J., Bergstrom R.G., DeGraft-Johnson D. Kinetics of drug decomposition by heat conduction calorimetry. Pharm. Res. 6:1989;20-27.
3. A. Wade, P.J. Weller, Handbook of Pharmaceutical Excipients, 2nd ed., American Pharmaceutical Association, Washington DC, USA, and The Pharmaceutical Press, London, England, 1994, pp. 257-260.
4. Castello R.A., Mattocks A.M. Discoloration of tablets containing amines and lactose. J. Pharm. Sci. 51:1962;106-108.