메뉴 건너뛰기




Volumn 14, Issue 2, 1999, Pages 106-111

High levels of maternal serum human chorionic gonadotropin in Down syndrome pregnancies: The possible role of a transcription factor on chromosome 21

Author keywords

Chromosome 21; Down syndrome; Human chorionic gonadotropin; Prenatal screening; Transcription factor

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; TRANSCRIPTION FACTOR;

EID: 0032966157     PISSN: 10153837     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020899     Document Type: Article
Times cited : (11)

References (25)
  • 3
    • 0023639762 scopus 로고
    • Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities
    • Bogart MH, Pandian MR, Jones OW: Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities. Prenat Diagn 1987;7:623-630.
    • (1987) Prenat Diagn , vol.7 , pp. 623-630
    • Bogart, M.H.1    Pandian, M.R.2    Jones, O.W.3
  • 5
    • 0028216064 scopus 로고
    • Reducing the need for amniocentesis in women 35 years of age or older with serum markers for screening (see comments)
    • Haddow JE, Palomaki GE, Knight GJ, Cunningham GC, Lustig LS, Boyd PA: Reducing the need for amniocentesis in women 35 years of age or older with serum markers for screening (see comments). N Engl J Med 1994;330: 1114-1118.
    • (1994) N Engl J Med , vol.330 , pp. 1114-1118
    • Haddow, J.E.1    Palomaki, G.E.2    Knight, G.J.3    Cunningham, G.C.4    Lustig, L.S.5    Boyd, P.A.6
  • 6
    • 0027461714 scopus 로고
    • Free alpha-subunit of human chorionic gonadotropin in down syndrome
    • Spencer K: Free alpha-subunit of human chorionic gonadotropin in Down syndrome. Am J Obstet Gynecol 1993;168:132-135.
    • (1993) Am J Obstet Gynecol , vol.168 , pp. 132-135
    • Spencer, K.1
  • 7
    • 0028884760 scopus 로고
    • Placental expression of alpha and beta subunits of human chorionic gonadotrophin in early pregnancies with down's syndrome
    • Brizot ML, Jauniaux E, McKie AT, Farzaneh F, Nicolaides KH: Placental expression of alpha and beta subunits of human chorionic gonadotrophin in early pregnancies with Down's syndrome. Hum Reprod 1995;10: 2506-2509.
    • (1995) Hum Reprod , vol.10 , pp. 2506-2509
    • Brizot, M.L.1    Jauniaux, E.2    McKie, A.T.3    Farzaneh, F.4    Nicolaides, K.H.5
  • 8
    • 0024240460 scopus 로고
    • Placental histology and the production of human choriogonadotrophin and its subunits in pregnancy
    • Hay DL: Placental histology and the production of human choriogonadotrophin and its subunits in pregnancy. Br J Obstet Gynaecol 1988;95:1268-1275.
    • (1988) Br J Obstet Gynaecol , vol.95 , pp. 1268-1275
    • Hay, D.L.1
  • 10
    • 0026389183 scopus 로고
    • Biochemistry and endocrinology of the down's syndrome pregnancy
    • Chard T: Biochemistry and endocrinology of the Down's syndrome pregnancy. Ann NY Acad Sci 1991;626:580-596.
    • (1991) Ann NY Acad Sci , vol.626 , pp. 580-596
    • Chard, T.1
  • 11
    • 0028790151 scopus 로고
    • High maternal serum chorionic gonadotropin level in down's syndrome pregnancies is caused by elevation of both subunits' messenger ribonucleic acid level in trophoblasts
    • Eldar-Geva T, Hochberg A, de Groot N, Weinstein D: High maternal serum chorionic gonadotropin level in Down's syndrome pregnancies is caused by elevation of both subunits' messenger ribonucleic acid level in trophoblasts. J Clin Endocrinol Metab 1995;80:3528-3531.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3528-3531
    • Eldar-Geva, T.1    Hochberg, A.2    De Groot, N.3    Weinstein, D.4
  • 12
    • 0021099901 scopus 로고
    • Imbalanced synthesis of human choriogonadotropin alpha and beta subunits reflects the steady state levels of the corresponding mRNAs
    • Boothby M, Kukowska J, Boime I: Imbalanced synthesis of human choriogonadotropin alpha and beta subunits reflects the steady state levels of the corresponding mRNAs. J Biol Chem 1983;258:9250-9253.
    • (1983) J Biol Chem , vol.258 , pp. 9250-9253
    • Boothby, M.1    Kukowska, J.2    Boime, I.3
  • 13
    • 0020473793 scopus 로고
    • Human chorionic gonadotropin beta-subunit is encoded by at least eight genes arranged in tandem and inverted pairs
    • Boorstein WR, Vamvakopoulos NC, Fiddes JC: Human chorionic gonadotropin beta-subunit is encoded by at least eight genes arranged in tandem and inverted pairs. Nature 1982; 300:419-422.
    • (1982) Nature , vol.300 , pp. 419-422
    • Boorstein, W.R.1    Vamvakopoulos, N.C.2    Fiddes, J.C.3
  • 14
    • 0023185803 scopus 로고
    • Cosmid mapping of the human chorionic gonadotropin beta subunit genes by field-inversion gel electrophoresis
    • Graham MY, Otani T, Boime I, Olson MV, Carle GF, Chaplin DD: Cosmid mapping of the human chorionic gonadotropin beta subunit genes by field-inversion gel electrophoresis. Nucleic Acids Res 1987;15:4437-4448.
    • (1987) Nucleic Acids Res , vol.15 , pp. 4437-4448
    • Graham, M.Y.1    Otani, T.2    Boime, I.3    Olson, M.V.4    Carle, G.F.5    Chaplin, D.D.6
  • 15
    • 0021771522 scopus 로고
    • Only three of the seven human chorionic gonadotropin beta subunit genes can be expressed in the placenta
    • Talmadge K, Boorstein WR, Vamvakopoulos NC, Gething MJ, Fiddes JC: Only three of the seven human chorionic gonadotropin beta subunit genes can be expressed in the placenta. Nucleic Acids Res 1984;12:8415-8436.
    • (1984) Nucleic Acids Res , vol.12 , pp. 8415-8436
    • Talmadge, K.1    Boorstein, W.R.2    Vamvakopoulos, N.C.3    Gething, M.J.4    Fiddes, J.C.5
  • 16
    • 0026767941 scopus 로고
    • Extraplacental human fetal tissues express mRNA transcripts encoding the human chorionic gonadotropin-beta subunit protein
    • Rothman PA, Chao VA, Taylor MR, Kuhn RW, Jaffe RB, Taylor RN: Extraplacental human fetal tissues express mRNA transcripts encoding the human chorionic gonadotropin-beta subunit protein. Mol Reprod Dev 1992; 33:1-6.
    • (1992) Mol Reprod Dev , vol.33 , pp. 1-6
    • Rothman, P.A.1    Chao, V.A.2    Taylor, M.R.3    Kuhn, R.W.4    Jaffe, R.B.5    Taylor, R.N.6
  • 21
    • 0023904208 scopus 로고
    • Identification of a promoter region in the CG beta gene cluster
    • erratum in: J Biol Chem 1988; 263:19256-19257
    • Otani T, Otani F, Krych M, Chaplin DD, Boime I: Identification of a promoter region in the CG beta gene cluster. J Biol Chem 1988; 263:7322-7329 (erratum in: J Biol Chem 1988; 263:19256-19257).
    • (1988) J Biol Chem , vol.263 , pp. 7322-7329
    • Otani, T.1    Otani, F.2    Krych, M.3    Chaplin, D.D.4    Boime, I.5
  • 22
    • 0029844709 scopus 로고    scopus 로고
    • The expression of the human chorionic gonadotropin beta subunit gene depends on negative control
    • Chen YH, Chen TM, Hsieh CY: The expression of the human chorionic gonadotropin beta subunit gene depends on negative control. Cell Biochem Funct 1996;14:297-301.
    • (1996) Cell Biochem Funct , vol.14 , pp. 297-301
    • Chen, Y.H.1    Chen, T.M.2    Hsieh, C.Y.3
  • 23
    • 0025145184 scopus 로고
    • Maternal serum down syndrome screening: Free beta-protein is a more effective marker than human chorionic gonadotropin (see comments)
    • Macri JN, Kasturi RV, Krantz DA, Cook EJ, Moore ND, Young JA, Romero K, Larsen JW Jr: Maternal serum Down syndrome screening: Free beta-protein is a more effective marker than human chorionic gonadotropin (see comments). Am J Obstet Gynecol 1990;163:1248-1253.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 1248-1253
    • Macri, J.N.1    Kasturi, R.V.2    Krantz, D.A.3    Cook, E.J.4    Moore, N.D.5    Young, J.A.6    Romero, K.7    Larsen Jw, J.8
  • 24
    • 0030027891 scopus 로고    scopus 로고
    • First-trimester down syndrome screening: Free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A
    • Krantz DA, Larsen JW, Buchanan PD, Macri JN: First-trimester Down syndrome screening: Free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A. Am J Obstet Gynecol 1996;174:612-616.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 612-616
    • Krantz, D.A.1    Larsen, J.W.2    Buchanan, P.D.3    Macri, J.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.