Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: Consequences for nonsteroidal antiinflammatory drug efficacy

FASEB Journal

Volumn 13, Issue 2, 1999, Pages 245-251

  Hamilton, Lorna C ^a   Mitchell, Jane A ^b   Tomlinson, Annette M ^a   Warner, Timothy D ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Antiinflammatory agents; Cyclooxygenase inhibitors; Disease models; Prostaglandin endoperoxide synthase; Prostaglandins

Indexed keywords

ARACHIDONIC ACID; BRADYKININ; CELECOXIB; CYCLOOXYGENASE 2; DICLOFENAC; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; RHEUMATOID ARTHRITIS;

ANIMALIA;

EID: 0032965577     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.2.245     Document Type: Article

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