One pot selective 5'-oxidation/olefination of 2'-deoxynucleosides

Synlett

Volumn , Issue 1, 1999, Pages 67-68

  Crich, David ^a   Mo, Xue Sheng ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Iodoxybenzoic acid; Nucleoside; Olefination; Oxidation

Indexed keywords

2' DEOXYNUCLEOSIDE; ALKENE;

AQUEOUS SOLUTION; ARTICLE; DERIVATIZATION; DRUG SYNTHESIS; DRUG TRANSFORMATION; NUCLEAR MAGNETIC RESONANCE; OXIDATION; REACTION ANALYSIS;

EID: 0032965033     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2550     Document Type: Article

References (8)

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2. Barrett, A. G. M.; Hamprecht, D.; Ohkubo, M. J. Org. Chem. 1997, 62, 9376.
3. Frigerio, M.; Santagostino, M. Tetrahedron Lett. 1994, 35, 8019.
4. Dess, D. B.; Martin, J. C. J. Am. Chem. Soc. 1991, 113, 7277.
5. Corey, E. J.; Palani, A. Tetrahedron Lett. 1995, 36, 3485.
6. Frigerio, M.; Santagostino, M.; Sputore, S.; Palmisano, G. J. Org. Chem. 1995, 60, 7272.
7. 3) δ 41.1, 46.8, 68.2, 74.1, 86.2, 87.6, 95.6, 120.3, 125.2, 126.3, 127.4, 128.2, 128.9, 129.0, 133.6, 137.4, 141.5, 143.4, 143.6, 143.8, 152.6, 162.8, 190.2. Anal. Calcd. for C32H27N3O6: C, 69.94; H, 4.95.
8. 4: C, 67.73; H, 6.50. Found: C, 67.52; H, 6.58%.