Comparison of pharmacokinetic profiles of doramectin and ivermectin pour-on formulations in cattle

Veterinary Parasitology

Volumn 81, Issue 1, 1999, Pages 47-55

  Gayrard, V ^a   Alvinerie, M ^b   Toutain, P L ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b CEMAGREF   (France)

Author keywords

Cattle; Doramectin; Ivermectin; Pharmacokinetics; Pour on

Indexed keywords

DORAMECTIN; IVERMECTIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CATTLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG FORMULATION; MALE; MEAN RESIDENCE TIME; NONHUMAN; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTHELMINTICS; AREA UNDER CURVE; BODY WEIGHT; CATTLE; CATTLE DISEASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IVERMECTIN; MALE;

ANIMALIA; BOS TAURUS;

EID: 0032962891     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4017(98)00236-2     Document Type: Article

References (17)

1. Alvinerie M., Sutra J.F., Badri M., Galtier P. Determination of moxidectin in plasma by high performance liquid chromatography with automated solid phase extraction and fluorescent detection. J. Chromatogr., B. 674:1995;119-124.
2. Bremner K.C., Berrie D.A. Persistence of anthelmintic activity of ivermectin in calves. Vet. Rec. 113:1983;569.
3. Campbell W.C., Benz G.W. Ivermectin: A review of efficacy and safety. J. Vet. Pharmacol. Therap. 7:1984;1-16.
4. Cardone M.J., Willavize S.A., Lacy M.E. Method validation revisited: A chemometric approach. Pharm. Res. 7:1990;154-160.
5. De Montigny P., Shim J.S.K., Pivnichy J.V. Liquid chromatography determination of ivermectin in animal plasma with trifluoacetic anhydride and N-methylimidazole as the derivatization agent. J. Pharm. Biomed. Anal. 8:1990;505-511.
6. Goudie A.C., Evans N.A., Gration K.A.F., Bishop B.F., Gibson S.P., Holdom K.S., Kaye B., Wicks S.R., Lewis D., Weatherley A.J., Bruce C.I., Herbert A., Seymour D.J. Doramectin - A potent novel endectocide. Vet. Parasitol. 49:1993;5-15.
7. Guillot F.S., Fred C.W., Delbert M.A., Oehler M.S. Concentration of ivermectin in bovine serum and its effect on the fecundity of psoroptic mange mites. Am. J. Vet. Res. 47:1986;525-527.
8. Herd R.P., Sams R.A., Ashcraft S.M. Persistence of ivermectin in plasma and faeces following treatment of cows with ivermectin sustained-release, pour-on or injectable formulations. Int. J. Parasitol. 26:1996;1087-1093.
9. McKellar Q.A., Benchaoui H.A. Avermectins and milbemycins. J. Vet. Pharmacol. Therap. 19:1996;331-351.
10. Nies, A.S., Spielberg, S.P., 1996. Principles of therapeutics, In: Hardman, J.G., Limbird, L.E., Molinoff, P.B., Ruddon, R.W., (Eds.), Goodman and Guilman's The Pharmacological Basis of Therapeutics, McGraw-Hill, New York, pp. 43-62.
11. Rowland, M., Tozer, T.N., 1995. In: Clinical Pharmacokinetics, Concepts and Application,. Williams and Wilkins, Baltimore, MD, p. 60.
12. Shah V.P., Midha K.K., Dighe S., McGilveray I.J., Skelly J.P., Yacobi A., Layloff T., Viswanathan C.T., Cook C.E., McDowall R.D., Pittman K.A., Spector S. Analytical methods validation: Bio-availability, bioequivalence and pharmacokinetic studies. Eur. J. Drug Metab. Pharmacokinet. 16:1991;249-255.
13. Toutain P.L., Upson D.W., Terhune T.N., McKenzie M.E. Comparative pharmacokinetics of doramectin and ivermectin in cattle. Vet. Parasitol. 72:1997;3-8.
14. Wilkinson P.K., Pope D.G., Baylis F.P. Pharmacokinetics of ivermectin administered intravenously to cattle. J. Pharm. Sci. 74:1985;1105-1107.
15. Yamaoka K., Nakagawa T., Uno T. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm. 6:1978;165-175.
16. Yamaoka K., Tanigawara K., Nakagawa T., Uno T. A pharmacokinetic analysis program (Multi) for microcomputer. J. Pharmacobiodyn. 4:1981;879-889.
17. Yazwinski T.A., Featherston H., Tucker C., Johnson Z. Residual nematocidal effectiveness of ivermectin in cattle. Am. J. Vet. Res. 55:1994;1416-1420.