Reoxygenation in quiescent and total intratumor cells following thermal neutron irradiation with or without 10B-compound - Compared with that after γ-ray irradiation

International Journal of Radiation Oncology Biology Physics

Volumn 44, Issue 2, 1999, Pages 391-398

  Masunaga, Shin Ichiro ^a   Ono, Koji ^a   Suzuki, Minoru ^a   Sakurai, Yoshinori ^a   Kobayashi, Tooru ^a   Takagaki, Masao ^a   Kinashi, Yuko ^a   Akaboshi, Mitsuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

10B compound; Hypoxic fraction; Neutron capture reaction; Potentially lethal damage; Quiescent cell

Indexed keywords

4 BORONOPHENYLALANINE B 10; BOROCAPTATE; BROXURIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CELL HYPOXIA; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GAMMA IRRADIATION; IMMUNOFLUORESCENCE; INTRAPERITONEAL DRUG ADMINISTRATION; MICRONUCLEUS TEST; MOUSE; NEUTRON RADIATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; REOXYGENATION; SQUAMOUS CELL CARCINOMA;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BORON; BORON NEUTRON CAPTURE THERAPY; BROMODEOXYURIDINE; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL HYPOXIA; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; ISOTOPES; LINEAR ENERGY TRANSFER; MICE; MICE, INBRED C3H; MICRONUCLEUS TESTS; OXYGEN CONSUMPTION; RADIATION-SENSITIZING AGENTS; RADIOBIOLOGY; REGRESSION ANALYSIS;

EID: 0032962871     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(99)00032-2     Document Type: Article

References (24)

1. Barth R.F., Soloway A.H., Brugger R.M. Boron neutron capture therapy of brain tumors past history, current status, and future potential . Cancer Invest. 14:1996;534-550.
2. Tannock T., Guttman P. Response of chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions. Br J Cancer. 43:1981;245-248.
3. Teicher B.A., Lazo J.S., Sartorelli A.S. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells. Cancer Res. 41:1981;73-81.
4. Murata R., Shibamoto Y., Sasai K., et al. Reoxygenation after single irradiation in rodent tumors of different types and sizes. Int J Radiat Oncol Biol Phys. 34:1996;859-865.
5. Dorie M.J., Kallman R.F. Reoxygenation in the RIF-1 tumor after chemotherapy. Int J Radiat Oncol Biol Phys. 24:1992;295-299.
6. Shibamoto Y., Kitakabu Y., Murata R., et al. Reoxygenation in the SCCVII tumor after KU-2285 sensitization plus single or fractionated irradiation. Int J Radiat Oncol Biol Phys. 29:1994;583-586.
7. Jackson R.C. The problem of the quiescent cancer cell. Adv Enz Regul. 29:1989;27-46.
8. Brown J.M., Giaccia A.J. The unique physiology of solid tumors opportunities (and problems) for cancer therapy . Cancer Res. 58:1998;1408-1416.
9. Masunaga S., Ono K., Abe M. A method for selective measurement of the radiosensitivity of quiescent cells in solid tumors - combination of immunofluorescence staining to BrdU and micronucleus assay. Radiat Res. 125:1991;243-247.
10. Kanda K. An overview radiation sources, beam quality, dosimetry and spectroscopy in neutron capture therapy . Strahlenther Onkol. 165:1989;67-69.
11. Caswell R.S., Coyne J.J., Radolph M.L. Kerma factors for neutron energies below 30 MeV. Radiat Res. 83:1980;217-254.
12. Snyder W.S., Cook M.J., Nasset E.S., et al. Gross and elemental content of reference man. Snyder W.S. Report of the Task Group on Reference Man. 1975;273-324 Pergamon Press, Oxford.
13. 10B concentrations and absorbed dose estimations in human malignant melanoma treated by BNCT. Strahlenther Onkol. 165:1989;104-106.
14. Ono K., Wandl E.O., Tsutsui K., et al. The correlation between cell survival and dose response curve of micronucleus (MN) frequency. Strahlenther Onkol. 165:1989;824-827.
15. Masunaga S., Ono K., Sakurai Y., et al. Responses of total and quiescent cell populations in solid tumors to boron and gadolinium neutron capture reaction using neutrons with two different energy spectra. Jpn J Cancer Res. 89:1998;81-88.
16. Masunaga S., Ono K., Akuta K., et al. The response of quiescent cell populations in murine solid tumors to irradiation with fast neutrons. Acta Oncol. 33:1994;813-817.
17. Masunaga S., Ono K., Wandl E.O., et al. Use of micronucleus assay for the selective detection of radiosensitivity in BUdR-unincorporated cells after pulselabelling of exponentially growing tumour cells. Int J Radiat Biol. 58:1990;303-311.
18. Brenner D.J., Hall E.J. Conditions for the equvalence of continuous to pulsed low dose-rate brachytherapy. Int J Radiat Oncol Biol Phys. 20:1991;181-190.
19. Cox J.D., Pajak T.F., Marcial V.A., et al. Interfraction interval is a major determinant of late effects, with hyperfractionated radiation therapy of carcinomas of upper respiratory and digestive tracts results from Radiation Therapy Oncology Group protocol 8313 . Int J Radiat Oncol Biol Phys. 20:1991;1191-1195.
20. Vaupel P., Kallinowski F., Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors a review . Cancer Res. 49:1989;6449-6465.
21. Kim I.H., Brown J.M. Reoxygenation and rehypoxiation in the SCC VII mouse tumor. Int J Radiat Oncol Biol Phys. 29:1994;493-497.
22. Olive P.L. Radiation-induced reoxygenation in the SCC VII murine tumour evidence for a decrease in oxygen consumption and an increase in tumour perfusion . Radiother Oncol. 32:1994;37-46.
23. Trotter M.J., Chaplin D.J., Durand R.E., et al. The use of fluorescent probes to identify regions of transient perfusion in murine tumors. Int J Radiat Oncol Biol Phys. 16:1989;931-934.
24. Masunaga S., Ono K., Abe M. The detection and modification of the hypoxic fraction in quiescent cell populations in murine solid tumours. Br J Radiol. 66:1993;918-926.