Activation of STAT1α by phosphatase inhibitor vanadate in glomerular mesangial cells: Involvement of tyrosine and serine phosphorylation

Journal of Receptor and Signal Transduction Research

Volumn 19, Issue 5, 1999, Pages 865-884

  Bardgette, John ^a   Abboud, Hanna E ^a   Ghosh Choudhury, Goutam ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MONOCLONAL ANTIBODY; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PHOSPHOSERINE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; SERINE; STAT1 PROTEIN; TYROSINE; VANADIC ACID;

ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA SYNTHESIS; GENE EXPRESSION; MESANGIUM CELL; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALIA; JANUS;

EID: 0032962826     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899909042878     Document Type: Article

References (32)

1. Shisheva A. and Shecjte Y. Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes. J. Biol. Chem. 26, 6463-6469, 1993.
2. Heyliger C. E., Tahilani A. G. and McNeil T. H. Effect of vanadate on elevated blood glucose and depressed cardiac performance in diabetic rats. Science 227, 1474-1476, 1995.
3. Meyerovitch j., Rothenberg J. P., Shechter Y., Bonner-Weir S. and Kahn C. R. Vanadate normalizes hyperglycemia in two mouse models of non-insulin dependent diabetes mellitus. J. Clin. Invest. 87, 1286-1294, 1991.
4. 2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J. Biol. Chem. 265, 2896-2902, 1990.
5. 2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and phosphoinositide breakdown in different cell lines. Biochemistry 29, 10240-10254, 1990.
6. Canalis E. Effect of sodium vanadate on deoxyribonucleic acid and protein synthesis in cultured rat calvariae. Endocrinology 116, 855-862, 1985.
7. Smith J. B. Vanadium ions stimulate DNA synthesis in Swiss 3T3 and 3T6 cells. Proc. Natl. Acad. Sci. USA 80, 6162-6166, 1983.
8. Rawson C., Cosola-Smith C., and Barnes D. Death of serum free mouse embryo cells caused by epidermal growth factor deprivation is prevented by cycloheximide, 12-O-tetradecanoylphorbol-13-acetate or vanadate. Exp. Cell Res. 186, 177-181, 1990.
9. Wice B., Milbrindt J. and Glaser L. Control of muscle differentiation in BC3H1 cells by fibroblast growth factor and vanadate. J. Biol. Chem. 262, 1810-1817, 1987.
10. Wenzel U. O., Fouqueray B., Biswas P., Grandaliano G., Ghosh Choudhury G. and Abboud H. E. Activation of mesangial cells by the phosphatase inhibitor vanadate . Potential implication of diabetic nephropathy. J. Clin. Invest. 95, 1244-1252, 1995.
11. Silver B., Jaffer F. E. and Abboud H. E. Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens. Proc. Natl. Acad. Sci. USA 86, 1056-1060, 1989.
12. Darnell J. E., Kerr I. M., and Stark G. R. JAK-STAT pathways and transcriptional activation in response to interferons and other extracellular signaling proteins. Science 264, 1415-1421, 1994.
13. Ihle J. N. STATs: Signal transducer and activators of transcription. Cell 84, 331-334, 1996.
14. Leman D. W., Leung S., Li X. and Stark G. R. Regulation of STAT dependent pathways by growth factors and cytokines. FASEB J. 10, 1578-1588, 1996.
15. Shuai K., Horvath C. M., Huang L. H. T., Qureshi S. A., Cowburn D. and Darnell J. E. Interferon activation of the transcription factor STAT91' involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 76, 821-828, 1994.
16. Glass W. P., Rampt J. A., Garoni J. W. and Kreisberg J. Regulation of mesangial cell adhesion and shape by thrombin. am. J. Physiol. 261, F336-F344, 1991.
17. Wagner B. J., Hayes T. E. Hoban C. J. and Cochran B. H. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 9, 4477-4484, 1990.
18. Marra F., Ghosh Choudhury G. and Abboud H. E. Interferon γ-mediated activation of STAT1a regulates growth factor-induced mitogenesis. J. Clin. Invest. 98, 1218-1230, 1996.
19. Ghosh Choudhury G., Ghosh-Choudhury N. and Abboud H. E. Association and direct activation of STAT1a by platelet-derived growth factor receptor. J. Clin. Invest. In Press
20. Ghosh Choudhury G., Marra F. and Abboud H. E. PDGF stimulates tyrosine phosphorylation of JAK1 protein tyrosine kinase in human mesangial cells. Kidney Int. 49, 19-25, 1996.
21. Ghosh Choudhury G., Wang L.-M., Pierce J. H., Harvey S. A. and Sakaguchi A. Y. A mutational analysis of phosphatidylinositol 3 kinase activation by human colony stimulating factor 1 receptor. J. Biol. Chem. 266, 8068-8072, 1991.
22. Wen Z. and Darnell J. E Mapping of STAT3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of STAT1 and STAT3. Nucleic Acid Res. 25, 2062-2067, 1997.
23. Zhu X., wen Z., Liang X. Z. and Darnell J. E. Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated JAK2 kinase. Mol Cell. Biol. 17, 6618-6623, 1997.
24. Ruff S. J. Chen K. and Cohen S. Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney. J. Biol. Chem. 272, 1263-1267, 1997.
25. Shisheva A. and Shechter Y. A cytosolic protein tyrosine kinase in rat adipocytes. FEBS Lett. 300, 93-96, 1992.
26. Shisheva A. and Shecheter Y. Quercetin selectively inhibits insulin receptor function in vitro and the bioresponses of insulin and insulinomimetic agents in rat adipocytes. Biochemistry 31, 8059-8063, 1992.
27. Secrist J. P. Burns L. A., Karnitz L. Korezky G. a and Abraham R. T. Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate , on T-cell activation events. J. Biol. Chem. 268, 5886-5893, 1993
28. Zhang X., Blenis J., Li H.-C., Schindler C. and Chen-King S. Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267, 1900-1904, 1995.
29. Wen Z., Zhong Z. and Darnell J. E. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82, 241-250, 1995.
30. Gonzales R. A., Raden D. L. and Davis R. J. Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases. J. Biol. Chem. 266, 22159-22163, 1991.
31. David M., Peticoin E., Benjamin C., Pine R., Weber M. J. and Larner A. C. Requirement of MAPK (ERK2) activity in interferon α-and interferon β stimulated gene expression through STAT proteins. Science 269, 1721-1723, 1995.
32. Chung J., Uchida E., Grammer T. C. and Blenis J. STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol. Cell. Biol. 17, 6508-6516, 1997.