Excitatory and inhibitory amino acid levels in the cerebrospinal fluids of children with neurological disorders

Acta Paediatrica Taiwanica

Volumn 40, Issue 2, 1999, Pages 65-69

  Shen, Ein Yiao ^a   Lai, Y U Jun ^a   Ho, Che Sheng ^a   Lee, Ying Liang ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Excitatory amino acids; Inhibitory amino acids; Meningitis encephalitis; Seizure

Indexed keywords

4 AMINOBUTYRIC ACID; EXCITATORY AMINO ACID; GLUTAMIC ACID; GLYCINE; TAURINE;

AMINO ACID ANALYSIS; AMINO ACID BRAIN LEVEL; ARTICLE; ASEPTIC MENINGITIS; BACTERIAL MENINGITIS; CEREBROSPINAL FLUID ANALYSIS; ENCEPHALITIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFANT; NERVE CELL; NEUROLOGIC DISEASE; PRESCHOOL CHILD; SEIZURE;

AMINO ACIDS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; ENCEPHALITIS; EXCITATORY AMINO ACIDS; HUMANS; MENINGITIS; NEUROTRANSMITTER AGENTS; SEIZURES;

EID: 0032962748     PISSN: 16088115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Ariadna VB, Cand MS, Igor AS. Amino acid composition of cerebrospinal fluid in acute neuroinfections in children. Arch Neurol 1975; 32:28-31.
2. Lappalainen R, Riikonen, High levels of cerebrospinal fluid glutamate in Rett syndrome. Pediatr Neurol 1996; 15:213-6.
3. Hagberg H, Thornberg E, Blennow M, Kjellmer I, Lagercrantz H, Thiringer K, Hamberger A, Sandberg M. Excitatory amino acids in the cerebropinal fluid of asphyxiated infants. Relationship to hypoxic-ischemic encephalopathy. Acta Paediatr 1993; 82:925-9.
4. Romero LG, Tureen JH, Fournier MA, Makvides V, Tauber MG. Amino acids in cerebrospinal and brain interstitial fluid in experimental pneumococal meningitis. Pediatr Res 1993; 33:510-3.
5. Rating D, Siemes H, Loscher W. Low CSF GABA concentration in children with febrile conculsion, untreated epilepsy, and meningitis. J Neurol 1983; 230:217-25.
6. Kal Viai nen R, Halonen T, Pitanen A, Riekkinen PJ. Amino acid levels in the cerebrospinal fluid of newly diagnosed epiceptic patients: Effect of vigabatrin and carbamazepine monotherapies. J. Neurochem 1993; 60:1244-50.
7. Halawa I, Baigs, Oureshi GA. Use of high performance liquid chromatography in defining the abnormalities in the free amino acid patterns in the cerebrospinal fluid of patients with aseptic meningitis. Biomed Chroma 1991; 5:216-20.
8. Crawford P, Uoyd K, Chardwick D CSF grdient for amino acid neurotransmitters J Neurol. Neurosurg, Psychiat 1988; 51:1193-200.
9. Spranger M, Krempien S, Schwab S, Maiwaled M, Bruno K, Hacke W. Excess glutamate in the cerebrospinal fluid in bacterial meningitis. J Neuro Sci 1996; 143:126-31.
10. Hagberg H, Andersson P, Kjellmer I, Thiringer K, Thordstein M. Extracelluar overflow of glutamate, aspartate, GABA and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia. Neurosci Letters 1987; 78:311-7.
11. Meldrum BS. The role of glutamate in epilepsy and other CNS disorders. Neurology 1994; 44(suppl 8):s14-20.
12. Baker A, Moulton RJ, MacMillan VH, Shedden PM. Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. J Neurosury 1993; 79:369-72.
13. Greenamyre JT, Young AB. Excitatory amino acid and Alzheimeris Disease. Neurobiol Aging 1989; 10:593-602.
14. Perry T, Kvieger C, Hansen S, Eisen A. Amyotrophic lateral sclerosis: amino acid levels in plasma and cerebrospinal fluid. Ann Neurol 1990; 28:12-7.
15. Young AB, Creenanyre TT, Hollings worth Z. NMDA receptor Losses in Putamen from Patients with Huntingfon's Disease, Science 1988; 241:981-3.
16. Shihabi ZK, White Jp. Liquid-Chromatographic Measurement of Taurine in Cerebrospinal Fluid of Normal Indiciduals and Patient with Meningitis. Clin Chem 1979; 25(8):1368-9.
17. Choi DW, Maulucci-Gedden M, Kviegstein AR. Glutamate Neurotoxicity in Cortical Cell Culture. J Neurosci 1987; 7:357-68.
18. Benveniste H, Dvejer J, Schousboe A, Diemer NH. Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus during Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis. J Neurochem 1984; 43:1369-74.
19. Ko FJ, Chiang CH, Liu WJ, Chiang W. Alteration of Amino Acid in Plasma and Cerebrospinal Fluid of Children with Seizure Disorder. Kaohsiung J Med Sci 1993; 9:131-42.
20. Gvove J, Palfreman M, Schedhter P. Cerebrospinal Fluid GABA as an Index of Brain GABA Activity. Clin Neurophamacol 1983; 6:223-9.
21. Manyam BV, Have TA. Cerebrospinal Fluid GABA Measurement; Basic and Clinical Consideration. Clin Neuropharmacol 1983; 6:25-36.