Pediatric AIDS-associated lymphocytic interstitial pneumonia and pulmonary arterio-occlusive disease. Role of VCAM-1/VLA-4 adhesion pathway and human herpesviruses

American Journal of Pathology

Volumn 154, Issue 5, 1999, Pages 1453-1464

  Brodie, Scott J ^a   De La Rosa, Corazon ^a   Howe, John Greg ^b   Crouch, Jill ^b   Travis, William D ^c   Diem, Kurt ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; VASCULAR CELL ADHESION MOLECULE 1;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CELL ADHESION; CELL INFILTRATION; CELL INTERACTION; CHILDHOOD DISEASE; CLINICAL ARTICLE; EPSTEIN BARR VIRUS; HUMAN; HUMAN TISSUE; INTERSTITIAL PNEUMONIA; LUNG INFILTRATE; LYMPHOCYTE ACTIVATION; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION; T LYMPHOCYTE SUBPOPULATION;

EID: 0032962376     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65400-4     Document Type: Article

References (67)

1. Bye MR, Cairns-Bazarian AM, Ewig JM: Markedly reduced mortality associated with corticosteroid therapy of Pneumocystis carinii pneumonia in children with acquired immune deficiency syndrome. Arch Pediatr Adolesc Med 1995, 148:638-641
2. Blanche S, Newell ML, Mayaux MJ, Dunn DT, Teglas JP, Rouzioux C, Peckham CS: Morbidity and mortality in European children vertically infected with HIV-1: the French Pediatric HIV Infection Study Group and European Collaborative Study. J Acquir Immune Defic Syndr Hum Retrovirol 1997, 14:442-450
3. Scott GB, Hutto C, Makuch RW, Mastrucci MT, O'Connor T, Mitchell CD, Trapido EJ, Parks WP: Survival in children with perinatally acquired immunodeficiency virus type 1 infection. N Engl J Med 1989, 321:1791-1796
4. Marolda J, Pace B, Bonforte RJ, Kotin NM, Rabinowitz J, Kattan M: Pulmonary manifestations of HIV infection in children. Pediatr Pulmonol 1991, 10:231-235
5. Moran CA, Suster S, Pavlova Z, Mullick FG, Koss MN: The spectrum of pathological changes in the lung in children with the acquired immunodeficiency syndrome: an autopsy study of 36 cases. Hum Pathol 1994, 25:877-882
6. McSherry GD: Human immunodeficiency-virus-related pulmonary infections in children. Semin Respir Infect 1996, 11:173-183
7. Pitt J: Lymphocytic interstitial pneumonia. Pediatr Clin North Am 1991, 38:89-95
8. Rubinstein A, Morecki R, Silverman B, Charytan M, Krieger BZ, Andiman W, Ziprkowski MN, Goldman H: Pulmonary disease in children with acquired immune deficiency syndrome and AIDS-related complex. J Pediatr 1986, 108:498-503
9. Joshi VV, Kauffman S, Oleske JM, Fikrig S, Denny T, Gadol C, Lee E: Polyclonal polymorphic B-cell lymphoproliferative disorder with prominent pulmonary involvement in children with acquired immune deficiency syndrome. Cancer 1987, 59:1455-1462
10. Joshi VV, Oleske JM, Connor EM: Morphologic findings in children with acquired immune deficiency syndrome: pathogenesis and clinical implications. Pediatr Pathol 1990, 10:155-165
11. Laurence J, Astrin SM: Human immunodeficiency virus induction of malignant transformation in human B lymphocytes. Proc Natl Acad Sci USA 1991, 88:7635-7639
12. Andiman WA, Eastman R, Martin K, Katz BZ, Rubinstein A, Pitt J, Miller G: Opportunistic lymphoproliferation associated with Epstein-Barr viral DNA in infants and children with AIDS. Lancet 1985, 2:1390-1393
13. Barbera JA, Hayashi S, Hegele RG, Hogg JC: Detection of Epstein-Barr virus in lymphocytic interstitial pneumonia by in situ hybridization. Am Rev Respir Dis 1992, 145:940-946
14. Hamilton-Dutoit SJ, Raphael M, Audouin J, Diebold J, Lisse I, Pedersen C, Oksenhendler E, Marelle L, Pallesen G: In situ demonstration of Epstein-Barr virus small RNAs (EBER-1) in acquired immunodeficiency syndrome-related lymphomas: correlation with tumor morphology and primary site. Blood 1993, 82:619-624
15. Nadal D, Caduff R, Frey E, Hassam S, Zimmermann DR, Seigneurin JM, Pluss HJ, Seger RA: Non-Hodgkin's lymphoma in four children infected with the human immunodeficiency virus: association with Epstein-Barr virus and treatment. Cancer 1994, 73:224-230
16. Toth FD, Mosborg-Peterson P, Kiss J, Aboagye-Mathiesen G, Hager H, Juhl CB, Gergely L, Zdravkovic M, Aranyosi J, Lampe L, Ebbesen P: Interactions between human immunodeficiency virus type 1 and human cytomegalovirus in human term syncytiotrophoblast cells coinfected with both viruses. J Virol 1995, 69:2223-2232
17. Griffiths PD: Herpesviruses and AIDS. J Antimicrob Chemother 1996, 37(Suppl B):87-95
18. Pleskoff O, Treboute C, Brelot A, Heveker N, Seman M, Alizon M: Identification of a chemokine receptor encoded by human cytomegalovirus as a cofactor for HIV-1 entry. Science 1997, 276:1874-1878
19. Picker LJ, Kishimoto TK, Smith CW, Warnock RA, Butcher EC: ELAM-1 is an adhesion molecule for skin homing T cells. Nature 1991, 349:796-799
20. Fries JWU, Williams AJ, Atkins RC, Newman W, Lipscomb MF, Collins T: Expression of VCAM-1 and E-selectin in an in vivo model of endothelial activation. Am J Pathol 1993, 143:725-737
21. Sasseville VG, Newman WA, Brodie SJ, Hesterberg P, Pauley D, Ringler DJ: Monocyte adhesion to endothelium in SIV-induced AIDS encephalitis is mediated by VCAM-1/α4β1 integrin interactions. Am J Pathol 1994, 144:27-40
22. Nakajima H, Sano H, Nishimura T, Yoshida S, Iwamoto I: Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue. J Exp Med 1995, 179:1145-1154
23. Carlos T, Kovach N, Schwartz B, Rosa M, Newman B, Wayner E, Benjamin C, Osborn L, Lobb R, Harlan J: Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule 1. Blood 1991, 77:2266-2271
24. Elices MJ, Osborn L, Takada Y, Crouse C, Luhowskyj S, Hemler ME, Lobb RR: VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 1990, 60:577-584
25. Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA Jr: Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 1993, 177:57-68
26. Issekutz TB, Miyasaka M, Issekutz AC: Rat blood neutrophils express very late antigen 4 and it mediates migration to arthritic joint and dermal inflammation. J Exp Med 1996, 183:2175-2184
27. Reinhardt PH, Elliott JF, Kubes P: Neutrophils can adhere via α4β1-integrin under flow conditions. Blood 1997, 89:3837-3846
28. Bevilacqua MP, Stengelin S, Gimbrone MA Jr, Seed B: Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989, 243:1160-1165
29. Ley K, Tedder TF: Leukocyte interactions with vascular endothelium: new insights into selectin-mediated attachment and rolling. J Immunol 1995, 155:525-528
30. Shimizu Y, Shaw S, Graber N, Gopal TV, Horgan KJ, Van Severnter GA, Newman W: Activation-independent binding of human memory T cells to adhesion molecule ELAM-1. Nature 1991, 349:799-802
31. Dustin ML, Springer TA: Lymphocyte function associated antigen-1 (LFA-1) interaction with intracellular adhesion adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. J Cell Biol 1988, 107:321-331
32. + T cell infiltration. J Immunol 1992, 149:2954-2960
33. Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N: Prevention of experimental autoimmune encephalitis by antibodies against α4β1 integrin. Nature 1992, 356:63-66
34. Brodie SJ, Sasseville VG, Reimann K, Simon MA, Sehgal PK, Ringler DJ: Macrophage function in simian AIDS: killing defects in vivo are independent of macrophage infection, associated with alterations in Th phenotype and are reversible with IFN-γ. J Immunol 1994, 153: 5790-5801
35. Brodie SJ, Pearson LD, Zink MC, Bickle HM, Anderson BC, Marcom KA, DeMartini JC: Ovine lentivirus expression and disease: virus replication, but not entry, is restricted to macrophages of specific tissues. Am J Pathol 1995, 146:1-13
36. Stamper HB Jr, Woodruff JJ: Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules. J Exp Med 1976, 144:828-833
37. Brodie SJ, Lewinsohn DA, Patterson BK, Jiyamapa D, Krieger J, Corey L, Greenberg PD, Riddell SR: In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nature Med, 1999, 5:34-41
38. Diamond C, Brodie SJ, Koelle DM, Meei-Li Huang, Diem K, Muthui D, Krieger JN, Corey L: Human herpes virus eight in prostate tissue on men with Kaposi's sarcoma. J Virol 1998, 72:6223-6227
39. Brodie SJ, Krieger JN, Diamond C, Diem K, Corey L: Kaposi's sarcoma associated human herpes virus eight: localization of viral gene expression and viral latency. Techniques in Localization of Gene Expression. Edited by Patterson BK. Boston, Birkhauser, 1999, in press
40. Fox CH, Fox M: In situ hybridization for detection of HIV RNA. Current Protocols in Immunology, vol 3. Edited by Coligan JE. New York, Wiley & Sons, 1993, pp 12.8.1-12.8.17
41. Chang KL, Chen YY, Shibata D, Weiss LM: Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues. Diagn Mol Pathol 1992, 1:246-255
42. Wu TC, Lee WA, Pizzorno MC, Au WC, Chan YJ, Hruban RH, Hutchins GM, Hayward GS: Localization of the human cytomegalovirus 2.7-kb major early β-gene transcripts by RNA in situ hybridization in permissive and nonpermissive infections. Am J Pathol 1992, 141:1247-1254
43. Brodie SJ, Marcom KA, Pearson LD, Anderson BC, de la Concha-Bermejillo A, Ellis JA, DeMartini JC: The effects of virus load in the pathogenesis of lentivirus-induced lymphoid interstitial pneumonia. J Infect Dis 1992, 166:531-541
44. Silber A, Newman W, Reimann KA, Hendricks E, Walsh D, Ringler DJ: Kinetic expression of endothelial adhesion molecules and relationship to leukocyte recruitment in two cutaneous models of inflammation. Lab Invest 1994, 70:163-175
45. Gould SJ, Isaacson PG: Bronchus-associated lymphoid tissue (BALT) in human fetal and infant lung. J Pathol 1993, 169:229-234
46. Travis WD, Fox CH, Devaney KO, Weiss LM, O'Leary TJ, Ognibene FP, Suffredini AF, Rosen MJ, Cohen MB, Shelhamer J: Lymphoid pneumonitis in 50 adult patients with the human immunodeficiency virus, lymphocytic interstitial pneumonitis versus nonspecific interstitial pneumonitis. Hum Pathol 1992, 23:529-541
47. Week KE, Dal-Canto AJ, Gould JD, O'Guin AK, Roth KA, Saffitz JE, Speck SH, Virgin HW: Murine γ-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-γ responsiveness: a new model for virus-induced vascular disease. Nature Med 1997, 3:1346-1353
48. Desrosiers RC, Sasseville VG, Czajak SC, Zhang X, Mansfield KG, Kaur A, Johnson RP, Lackner AA, Jung JU: A herpesvirus of rhesus monkeys related to human Kaposi's sarcoma-associated herpesvirus. J Virol 1997, 71:9764-9769
49. Drut R, Drut RM: EBV-associated sarcoma in a pediatric renal transplant recipient. Pediatr Pathol 1994, 14:863-872
50. Sperduto AR, Bryson YJ, Chen ISY: Increased susceptibility of neonatal monocyte/macrophages to HIV-1 infection. AIDS Res Hum Retrovir 1993, 9:1277-1285
51. Pearce TE, Nowakowski M, Eden E, Huang ZB, Steiner P, Shahabuddin M, Potash MJ, Volsky DJ: Uniform detection of HIV-1 in alveolar macrophages of pediatric but not adult AIDS patients. J Leukoc Biol 1993, 53:722-726
52. Sei S, Akiyoshi H, Bernard J, Venzon DJ, Fox CH, Schwartzentruber DJ, Anderson BD, Kopp JB, Mueller BU, Pizzo PA: Dynamics of virus versus host interaction in children with human immunodeficiency infection type 1 infection. J Infect Dis 1996, 173:1485-1490
53. Graber N, Gopal TV, Wilson D, Beall LD, Polte T, Newman W: T cells bind to cytokine-activated endothelial cells via a novel, inducible sialoglycoprotein and endothelial leukocyte adhesion molecule-1. J Immunol 1990, 145:819-830
54. Koss MN: Pulmonary lymphoid disorders. Semin Diagn Pathol 1995, 12:158-171
55. Birx DL, Redfield RR, Tosato G: Defective regulation of Epstein-Barr virus infection in patients with AIDS or AIDS-related disorders. N Engl J Med 1986, 314:874-879
56. Carbone A, Gloghini A, Volpe R, Boiocchi M, Tirelli U: High frequency of Epstein-Barr virus latent membrane protein-1 expression in acquired immunodeficiency syndrome-related Ki-1 (CD30)-positive anaplastic large-cell lymphomas. Am J Clin Pathol 1994, 101:768-772
57. Banerjee D, Ahmad D: Malignant lymphoma complicating lymphocytic interstitial pneumonia: a monoclonal B-cell neoplasm arising in a polyclonal lymphoproliferative disorder. Hum Pathol 1982, 13:780-782
58. Chalifoux LV, Simon MA, Pauley DR, MacKey JJ, Wyand MS, Ringler DJ: Arteriopathy in macaques infected with simian immunodeficiency virus. Lab Invest 1992, 67:338-349
59. Tinkle BT, Ngo L, Luciw PA, Maciag T, Jay G: Human immunodeficiency virus-associated vasculopathy in transgenic mice. J Virol 1997, 71:4809-4814
60. Albini A, Barillari G, Benelli R, Gallo RC, Ensoli B: Angiogenic properties of human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci USA 1995, 92:4838-4842
61. Moore PS, Chang Y: Detection of human herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and those without HIV infection. N Engl J Med 1995, 332:1181-1185
62. Salahuddin SZ, Nakamura S, Biberfield P, Kaplan MH, Markham PD, Larsson L, Gallo RC: Angiogenic properties of Kaposi's sarcoma-derived cells after long-term culture in vitro. Science 1988, 242:430-433
63. Barillari G, Buonaguro L, Fiorelli V, Huffman J, Michaels F, Gallo RC, Ensoli B: Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression: implications for AIDS-Kaposi's sarcoma pathogenesis. J Immunol 1992, 149:3727-3734
64. Cen H, Williams PA, McWilliams HP, Breinig MC, Ho M, McKnight JL: Evidence for restricted Epstein-Barr virus latent gene expression and anti-EBNA antibody response in solid organ transplant recipients with posttransplant lymphoproliferative disorders. Blood 1993, 81:1393-1403
65. Tanaka S, Komori K, Okadome K, Sugimachi K, Mori R: Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction. J Vasc Surg 1994, 20:235-243
66. Lathey JL, Spector DH, Spector SA: Human cytomegalovirus-mediated enhancement of human immunodeficiency virus type-1 production in monocyte-derived macrophages. Virology 1994, 199:98-104
67. Yonemitsu Y, Nakagawa K, Tanaka S, Mori R, Sigimachi K, Sueishi K: In situ detection of frequent and active infection of human cytomegalovirus in inflammatory abdominal aortic aneurysms: possible pathogenic role in sustained chronic inflammatory reaction. Lab Invest 1996, 74:723-736