Biochemical markers of bone turnover do not decline after menopause in healthy women

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 106, Issue 5, 1999, Pages 427-431

  Takahashi, Masaaki ^a   Kushida, Kazuhiro ^a   Hoshino, Hironobu ^a   Ohishi, Tsuyoshi ^a   Inoue, Tetsuo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE BONE ISOENZYME; COLLAGEN TYPE 1; DEOXYPYRIDINOLINE; OSTEOCALCIN; PROCOLLAGEN;

ADULT; AGED; ARTICLE; BONE MASS; BONE TURNOVER; CALCANEUS; CONTROLLED STUDY; DENSITOMETRY; FEMALE; HUMAN; JAPAN; MENOPAUSE; NORMAL HUMAN; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; ULTRASOUND;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BONE RESORPTION; FEMALE; HUMANS; MIDDLE AGED; POSTMENOPAUSE; PREMENOPAUSE; TIME FACTORS;

EID: 0032960995     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.1999.tb08295.x     Document Type: Article

References (20)

1. Garnero P, Somay-Rendu E, Chapuy SR, Delmas PD. Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 1996; 11: 337-349.
2. Ohishi T, Takahashi M, Kawana K, Aoshima H, Hoshino H, Horiuchi K et al. Age related changes of urinary pyridinoline and deoxypyridinoline in Japanese subjects. Clin Invest Med 1993; 16: 319-325.
3. Pino J, Martin-Rodriguez M, Lopez-Sosa C, Cordero M, Lanchares JL, Garcia-Talavera JR. Influence of sex, age, and menopause in serum osteocalcin (BGP) levels. Klin Wochenschr 1991; 69: 1135-1138.
4. Seibel MJ, Woitge H, Scheidt-Nave C, Leidig-Bruckner G, Duncan A, Nicol P et al. Urinary hydroxypyridinium crosslinks of collagen in population-based screening for overt vertebral osteoporosis: results of a pilot study. J Bone Miner Res 1994; 9: 1433-1440.
5. Sokoll LJ, Sadowski JA. Comparison of biochemical indexes for assessing vitamin K nutritional status in a healthy adult population. Am J Clin Nutr 1996; 63: 566-573.
6. The Committee on Enzymes of the Scandinavian Society for Clinical Chemistry and Clinical Physiology. Recommended methods for the determination of four Enzymes in blood. Scand J Clin Lab Invest 1974; 33:291-306.
7. Gomez BJ, Ardakani S, Ju J, Jenkins D, Cerelli MJ, Daniloff GY et al. Monoclonal antibody assay for measuring bone specific alkaline phosphatase activity in serum. Clin Chem 1995; 41: 1560-1566.
8. Masters PW, Jones RG, Purves DA, Cooper EH, Cooney JM. Commercial assays for serum osteocalcin give clinically discordant results. Clin Chem 1994; 40: 358-363.
9. Parfitt AM, Simon LS, Villanueva AR, Simon SM. Procollagen type I carboxyterminal extension peptide in serum as a marker of collagen biosynthesis in bone. Correlation with iliac bone formation rates and comparison with total alkaline phosphatase. J Bone Miner Res 1987; 2: 427-436.
10. Seibel MJ, Cosman F, Shen V, Ratcliffe A, Lindsay R. Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis. J Bone Miner Res 1993; 8: 881-889.
11. Bonde M, Qvist P, Fledelius C, Riis BJ, Christiansen C. Immunoassay for quantifying type I collagen degradation products in urine evaluated. Clin Chem 1994; 40: 2022-2025.
12. Wand JS, Green JR, Hesp R, Bradbeer JN, Sambrook PN, Smith T et al. Bone remodelling does not decline after menopause in vertebral fracture osteoporosis. Bone Miner 1992; 17: 361-375.
13. Kushida K, Takahashi M, Kawana K, Inoue T. Comparison of markers for bone formation and resorption in premenopausal and post menopausal subjects, and osteoporosis patients. J Clin Endocrinol Metab 1995; 80: 2447-2450.
14. Takahashi M, Kushida K, Hoshino H, Ohishi T. Inoue T. Evaluation of bone turnover in postmenopause, vertebral fractures, and hip fracture using biochemical markers for bone formation and resorption. J Endocrinol Invest 1997; 20: 112-117.
15. Nilas L, Christiansen C. The pathophysiology of pen- and post menopausal bone loss. Br J Obsret Gynaecol 1989; 96: 580-587.
16. Kawana K, Kushida K, Takahashi M, Obishi T, Denda M, Yamazaki K et al. The effect of menopause on biochemical markers and ultrasound densitometry in healthy females. Calcif Tissue Int 1994; 55: 420-425.
17. Kelly PJ, Pocock NA, Sambrook PN, Eisman JA. Age and menopause-related changes in indices of bone turnover. J Clin Endocrinol Metab 1989 69: 1160-1165.
18. Yasumura S, Aloia JF, Gundberg CM, Yeh J, Vaswani AN, Yuen K et al. Serum osteocalcin and total body calcium in normal pre- and post menopausal women and postmenopausal osteoporotic patients. J Clin Endocrinol Metab 1987; 64: 681-685.
19. Melton ILILJ, Khosla S, Atkinson El, O’Fallon WM, Riggs BL. Relationship of bone tumover to bone density and fractures. J Bone Miner Res 1997; 12: 1083-1091.
20. Takahashi M, Kushida K, Hoshino H, Miura M, Ohishi T, Inoue T. Comparison of bone and total alkaline phosphatase activity on bone tumover during menopause and in patients with established osteoporosis. Clin Endocrinol 1997; 47: 177-183.