Transcriptional organization of the czc heavy-metal homeostasis determinant from Alcaligenes eutrophus

Journal of Bacteriology

Volumn 181, Issue 8, 1999, Pages 2385-2393

  Große, Cornelia ^a   Grass, Gregor ^a   Anton, Andreas ^a   Franke, Sylvia ^a   Santos, Alexander Navarrete ^a   Lawley, Blair ^b   Brown, Nigel L ^b   Nies, Dietrich H ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA SEQUENCE; HEAVY METAL POISONING; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; TRANSCRIPTION REGULATION; WAUTERSIA EUTROPHA;

ALCALIGENES; ALCALIGENES EUTROPHUS; NEGIBACTERIA; PROKARYOTA; WAUTERSIA EUTROPHA;

EID: 0032959708     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.8.2385-2393.1999     Document Type: Article

References (38)

1. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
2. De Las Penas, A., L. Connolly, and C. A. Gross. 1997. The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. Mol. Microbiol. 24:373-385.
3. Diels, L., Q. Dong, D. van der Lelie, W. Baeyens, and M. Mergeay. 1995. The czc operon of Alcaligenes eutrophus CH34: from resistance mechanism to the removal of heavy metals. J. Ind. Microbiol. 14:142-153.
4. Dressier, C., U. Kües, D. H. Nies, and B. Friedrich. 1991. Determinants encoding multiple metal resistance in newly isolated copper-resistant bacteria. Appl. Environ. Microbiol. 57:3079-3085.
5. Engler-Blum, G., M. Meier, J. Frank, and G. A. Müller. 1993. Reduction of background problems in nonradioactive Northern and Southern blot analysis enables higher sensitivity than 32P-based hybridizations. Anal. Biochem. 210:235-244.
6. Kunito, T., T. Kusano, H. Oyaizu, K. Senoo, S. Kanazawa, and S. Matsumoto. 1996. Cloning and sequence analysis of czc genes in Alcaligenes sp. strain CT14. Biosci. Biotechnol. Biochem. 60:699-704.
7. Lenz, O., E. Schwartz, J. Dernedde, T. Eitinger, and B. Friedrich. 1994 The Alcaligenes eutrophus H16 hoxX gene participates in hydrogenase regulation. J. Bacteriol. 176:4385-4393.
8. Liesegang, H., K. Lemke, R. A. Siddiqui, and H.-G. Schlegel. 1993. Characterization of the inducible nickel and cobalt resistance determinant cnr from pMOL28 of Alcaligenes eutrophus CH34. J. Bacteriol. 175:767-778.
9. Lonelto, M. A., K. L. Brown, K. E. Rudd, and M. J. Buttner. 1994. Analysis of the Streptomyces coelicolor sigF gene reveals the existence of a subfamily of eubacterial RNA polymerase a factors involved in the regulation of extracytoplasmic functions. Proc. Natl. Acad. Sci. USA 91:7573-7577.
10. Mergeay, M., D. Nies, H. G. Schlegel, J. Gerits, P. Charles, and F. van Gijsegem. 1985. Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals. J. Bacteriol. 162:328-334.
11. Michaelian, I., and A. Sergeant. 1992. A general and fast method to generate multiple site directed mutations. Nucleic Acids Res. 20:376.
12. Mills, S. D., C.-K. Lim, and D. A. Cooksey. 1994. Purification and characterization of CopR, a transcriptional activator protein that binds to a conserved domain (cop box) in copper-inducible promoters of Pseudomonas syringae. Mol. Gen. Genet. 244:341-351.
13. Missiakas, D., and S. Raina. 1998. The extracytoplasmic function sigma factors: role and regulation. Mol. Microbiol. 28:1059-1066.
14. Navarrete Santos, A., A. Kehlen, W. Schütte, L. Langner, and D. Riemann. 1998. Regulation by transforming growth factor β1 of class II mRNA and protein expression in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Int. Immunol. 10:601-607.
15. Nicholson, M. L., and D. E. Laudenbach. 1995. Genes encoded on a cyanobacterial plasmid are transcriptionally regulated by sulfur availability and CysR. J Bacteriol. 177:2143-2150.
16. Nies, A., D. H. Nies, and S. Silver. 1989. Cloning and expression of plasmid genes encoding resistance to chromate and cobalt in Alcaligenes eutrophus. J. Bacteriol. 171:5065-5070.
17. Nies, D., M. Mergeay, B. Friedrich, and H. G. Schlegel. 1987. Cloning of plasmid genes encoding resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus CH34. J. Bacteriol. 169:4865-4868.
18. Nies, D. H. 1995. The cobalt, zinc, and cadmium efflux system CzcABC from Alcaligenes eutrophus functions as a cation-proton antiporter in Escherichia coli. J. Bacteriol. 177:2707-2712.
19. Nies, D. H. 1992. CzcR and CzcD, gene products affecting regulation of resistance to cobalt, zinc and cadmium (czc system) in Alcaligenes eutrophus. J. Bacteriol. 174:8102-8110.
20. Nies, D. H. 1992. Resistance to cadmium, cobalt, zinc and nickel in microbes. Plasmid 27:17-28.
21. Nies, D. H., and N. Brown. 1997. Two-component systems in the regulation of heavy metal resistance. In S. Silver and W. Walden (ed.). Metal ions in gene regulation. Chapman & Hall, London, England.
22. Nies, D. H., A. Nies, L. Chu, and S. Silver. 1989. Expression and nucleotide sequence of a plasmid-determined divalent cation efflux system from Alcaligenes eutrophus. Proc. Natl. Acad. Sci. USA 86:7351-7355.
23. Nies, D. H., and S. Silver. 1989. Plasmid-determined inducible efflux is responsible for resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus. J. Bacteriol. 171:896-900.
24. Oelmüller, U., N. Krüger, A. Steinbüchel, and C. G. Friedrich. 1990. Isolation of prokaryotic RNA and detection of specific mRNA with biotinylated probes. J. Microbiol. Methods 11:73-84.
25. Peitzsch, N., and D. H. Nies. Unpublished data.
26. Rensing, C., T. Pribyl, and D. H. Nies. 1997. New functions for the three subunits of the CzcCBA cation-proton antiporter. J. Bacteriol. 179:6871-6879.
27. Rouch, D. A., and N. L. Brown. 1997. Copper-inducible transcriptional regulation at two promoters in the Escherichia coli copper resistance determinant pco. Microbiology 143:1191-1202.
28. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
29. Schmidt, T., and H. G. Schlegel. 1994. Combined nickel-cobalt-cadmium resistance encoded by the ncc locus of Alcaligenes xylosoxidans 31A. J. Bacteriol. 176:7045-7054.
30. Simon, R., U. Priefer, and A. Pühler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram-negative bacteria. Bio/Technology 1:784-791.
31. Simon, R., J. Quandt, and W. Klipp. 1989. New derivatives of transposon Tn5 suitable for mobilization of replicons, generation of operon fusions and induction of genes in Gram-negative bacteria. Gene 80:161-169.
32. Snavely, M. D., C. G. Miller, and M. E. Maguire. 1991. The mgtB Mg2+ transport locus of Salmonella typhimurium encodes a P-type ATPase. J. Biol. Chem. 266:815-823.
33. Tabor, S. Personal communication.
34. Tabor, S., and C. C. Richardson. 1985. A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. Proc. Nail. Acad. Sci. USA 82:1074-1078.
35. Taghavi, S., M. Mergeay, and D. Van der Lelie. 1997. Genetic and physical map of the Alcaligenes eutrophus CH34 megaplasmid pMOL28 and it derivative pMOL50 obtained after temperature induced mutagenesis and mortality. Plasmid 37:22-34.
36. Van der Lelie, D., T. Schwuchow, U. Schwidetzky, S. Wuertz, W. Baeyens, M. Mergeay, and D. H. Nies. 1997. Two component regulatory system involved in transcriptional control of heavy metal homeostasis in Alcaligenes eutrophus. Mol. Microbiol. 23:493-503.
37. Voss, H., U. Wirkner, R. Jakobi, N. A. Hewitt, C. Schwager, J. Zimmermann, W. Ansorge, and W. Pyerin. 1991. Structure of the gene encoding human casein kinase II subunit β. J. Biol. Chem. 266:13706-13711.
38. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.