MUC1 expression in intramucosal colorectal neoplasms. Possible involvement in histogenesis and progression

Oncology

Volumn 56, Issue 3, 1999, Pages 223-231

  Tanimoto, Tatsuro ^a   Tanaka, Shinji ^a   Haruma, Ken ^a   Yoshihara, Masaharu ^a   Sumii, Koji ^a   Kajiyama, Goro ^a   Shimamoto, Fumio ^b   Kohno, Nobuoki ^c  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Colorectal carcinoma; Histogenesis; Ki 67; MUC1; p53

Indexed keywords

DNA; KI 67 ANTIGEN; MUCIN; PROTEIN P53;

APOPTOSIS; ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA NICK TRANSLATION; HISTOGENESIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032959378     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000011969     Document Type: Article

References (45)

1. Dahiya R, Kwak K-S, Byrd JC, Ho S, Yoon W-H, Kim YS: Mucin synthesis and secretion in various human epithelial cancer cell lines that express the MUC-1 mucin gene. Cancer Res 1993;53:1437-1443.
2. Gendler SJ, Spicer AP, Lalani EN, Duhig T, Peat N, Burchell J, Pemberton L, Boshell M, Taylor-Papadimitriou J: Structure and biology of a carcinoma-associated mucin, MUC1. Am Rev Respir Dis 1991;144:S42-47.
3. Peat N, Gendler SJ, Lalani EN, Duhing T, Taylor-Papadimitriou J: Tissue-specific expression of a human polymorphic epithelial mucin (MUC-1) in transgenic mice. Cancer Res 1992; 52:1954-1960.
4. Nakamori S, Ota DM, Cleary KR, Shirotani K, Irimura T: MUC1 mucin expression as a marker of progression and metastasis of human coloaectal carcinoma. Gastroenterology 1994;106: 353-361.
5. Ogata S, Uehara H, Chen A, Itzkowitz SH: Mucin gene expression in colonie tissues and cell lines. Cancer Res 1992;52:5971-5978.
6. Irimura T, Carlson DA, Price J, Yamori T, Giavazzi R, Ota DM, Cleary KR: Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues. Cancer Res 1988;48:2353-2360.
7. Yuan M: Mucin core peptide expression in malignant and non-malignant colorectal tissues (in Chinese, English abstract). Chung Hua Chung Liu Tsa Chih 1992;14:267-269.
8. Kohno N, Awaya Y, Oyama T, Yamakido M, Akiyama M, Inoue Y, Yokoyama A, Hamada H, Fujioka S, Hiwada K: KL-6, a mucin-like glycoprotein, in bronchoalveolar lavage fluid from patients with interstitial lung disease. Am Rev Respir Dis 1993;148:637-642.
9. Kohno N, Akiyama M, Kyoizumi S, Hakoda M, Kobuke K, Yamakido M: Detection of soluble tumor-associated antigens in sera and effusions using novel monoclonal antibodies, KL-3 and KL-6, against lung adenocarcinoma. Jpn J Clin Oncol 1988;18:203-216.
10. Makiguchi Y, Hinoda Y, Imai K: Effect of MUC1 mucin, an anti-adhesion molecule, on tumor cell growth. Jpn J Cancer Res 1996;87: 505-511.
11. Wesseling J, van der Valk SW, Vos HL, Sonnenberg A, Hilkens J: Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components. J Cell Biol 1995;129:255-265.
12. Ajioka Y, Allison LJ, Jass JR: Significance of MUC1 and MUC2 mucin expression in colorectal cancer. J Clin Pathol 1996;49:560-564.
13. Ajioka Y, Watanabe, H, Jass JR: MUC1 and MUC2 mucins in flat and polypoid colorectal adenomas. J Cin Pathol 1997;50:417-421.
14. Tanaka S, Haruma K, Tatsuta S, Hiraga Y, Teixeira CR, Shimamoto F, Yoshihara M, Sumii K, Kajiyama G: Proliferating cell nuclear antigen expression correlates with the metastatic potential of submucosal invasive colorecta carcinoma. Oncology 1995;52:134-139.
15. Teixeira CR, Tanaka S, Haruma K, Yoshihara M, Sumii K, Kajiyama G: Proliferating cell nuclear antigen (PCNA) expression at the invasive tumor margin predicts malignant potential of colorectal carcinomas. Cancer 1994;73:575-579.
16. Stewart BW: Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators. J Natl Cancer Inst 1994;86:1286-1296.
17. Chandler D, el Naggar AK, Brisbay S, Redline RW, McDonnell TJ: Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: Evidence for the contribution of bcl-2 expression to renal carcinogenesis. Hum Pathol 1994;25:789-796.
18. Fritsche M, Haessler C, Brandner G: Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 1993;8:307-318.
19. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993;362:847-849.
20. Hall PA, McKee PH, Menage HP, Dover R, Lane DP: High levels of p53 in UV-irradiated normal human skin. Oncogene 1993;8:203-207.
21. Yamagata S, Muto T, Uchida Y, Masaki T, Higuchi Y, Sawada T, Hirooka T: Polypoid growth and K-ras codon 12 mutation in colorectal cancer. Cancer 1995;75:953-957.
22. Minamoto T, Sawaguchi K, Mai M, Yamashita N, Sugimura T, Esumi H: Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res 1994;54:2841-2844.
23. Yamagata S, Muto T, Uchida Y, Masaki T, Sawada T, Tsuno N, Hirooka T: Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas. Jpn J Cancer Res 1994;85:147-151.
24. Morson BC: Precancerous and early malignant lesions of the large intestine. Br J Surg 1968;55: 725-731.
25. Muto T, Bussey H Jr, Morson BC: The evolution of cancer of the colon and rectum. Cancer 1975;36:2251-2270.
26. Shimoda T, Ikegami M, Fujisaki J, Matsui T, Aizawa S, Ishikawa E: Early colorectal carcinoma with special reference to its development de novo. Cancer 1989;64:1138-1146.
27. Herrera L, Hanna S, Castillo N, Petrelli NJ: Primary de novo adenocarcinoma of the colon measuring 8 mm in diameter with lymph node metastasis. Dis Colon Rectum 1991;34:275-279.
28. Irimura T, Matsushita Y, Hoff SD, Yamori T, Nakamori S, Frazier ML, Giacco GG, Cleary KR, Ota DM: Ectopic expression of mucins in colorectal cancer metastasis. Cancer Biol 1991; 2:129-139.
29. Hiraga Y, Tanaka S, Haruma K, Yoshihara M, Sumii K, Kajiyama G, Shimamoto F, Kohno N: Immunoreactive MUC1 expression at the deepest invasive portion correlates with prognosis of colorectal cancer. Oncology 1998;55: 307-319.
30. Hermanek P, Sobin LH (eds): International Union Against Cancer, TNM Classification of Malignant Tumors. Berlin, Springer, 1987, pp 47-49.
31. Japanese Society for Cancer of the Colon and Rectum: Japanese Classification of Colorectal Carcinoma. Tokyo, Kanehara, 1997.
32. Yukawa M, Fujimori T, Maeda S, Tabuchi M, Nagasako K: Comparative clinicopathological and immunohistochemical study of ras and p53 in flat and polypoid type colorectal tumours. Gut 1994;35:1258-1261.
33. Kudo S: Endoscopic mucosal resection of flat and depressed types of early colorectal cancer. Endoscopy 1993;25:455-461.
34. Teixeira CR, Tanaka S, Haruma K, Yoshihara M, Sumii K, Kajiyama G, Shimamoto F: Flatelevated colorectal neoplasms exhibit a high malignant potential. Oncology 1996;53:89-93.
35. Okamoto T, Tanaka S, Haruma K, Hiraga Y, Kunihiro M, Goishi H, Tanimoto T, Sumii M, Yoshihara M, Sumii K, Kajiyama G, Shimamoto F: Clinicopathologic evaluation on colorectal laterally spreading tumor (LST) (in Japanese with English abstract). Jpn J Gastroenterol 1996;93:83-89.
36. Jass JR, Sobin LH: Histological typing of intestinal tumors. World Health Organization. International Classification of Tumors. New York, Springer, 1989.
37. Watanabe H, Ajioka Y, Yamaguchi M, Noda Y, Honma T, Motoyama T: Histological criteria of colorectal adenomas and carcinomas (in Japanese with English abstract). Stomach Intest 1989;24:253-259.
38. Kohno N, Inoue Y, Hamada H, Fujioka S, Fujino S, Yokoyama A, Hiwada K, Ueda N, Akiyama M: Difference in sero-diagnostic values among KL-6-associated mucins classified as cluster 9. Int J Cancer 1994;(suppl 8):81-83.
39. Kohno N, Hamada H, Fujioka S, Hiwada K, Yamakido M, Akiyama M: Circulating antigen KL-6 and lactate dehydrogenase for monitoring irradiated patients with lung cancer. Chest 1992;102:117-122.
40. Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
41. Fujimori T, Nagasako K, Satonaka K, Hirayama D, Harada M, Muratani A, Tabata T, Kitazawa S, Ikehara H, Maeda S: Expression of ras oncogene product (p21) and point mutation of Ki-ras codon 12 in superficial early colorectal cancer (in Japanese). Stomach Intest 1992;27: 111-117.
42. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smiths AMM, Bos JL: Genetic alterations during colorectal tumor development. N Engl J Med 1988;319:525-532.
43. Baker SJ, Preisinger AC, Jessup JM, Paraskeva C, Markowitz SJ, Willson JKV, Hamilton S, Vogelstein B: p53 gene mutations occur in combination with p17 allelic deletions as late events in colorectal tumorigenesis. Cancer Res 1990;50:7717-7722.
44. Agrawal B, Krantz MJ, Reddish MA, Longenecker BM: Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2. Nat Med 1998;4:43-49.
45. Gimmi CD, Morrison BW, Mainprice BA, Gribben JG, Boussiotis VA, Freeman GJ, Park SY, Watanabe M, Gong J, Hayes DF, Kufe DW, Nadler LM: Breast cancer-associated antigen, DF3/MUC1, induces apoptosis of activated human T cells. Nat Med 1996;2:1367-1370.