Heterogeneity of in vitro radiosensitivity in human bladder cancer cells

Radiation Oncology Investigations

Volumn 7, Issue 2, 1999, Pages 66-76

  Barnetson, Anthony R ^a,b   Banasiak, Dorota ^a,b   Fisher, Richard J ^a   Mameghan, Hedy ^c   Ribeiro, Julio C C ^a,b   Brown, Keith ^a,b   Brown, Joanne L ^a,b   O'Mara, Shaun M ^a,b   Russell, Pamela J ^a,b  

^a PRINCE OF WALES HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Bladder cancer; Clonogenic assay; Heterogeneity; MTT assay; Radiosensitivity

Indexed keywords

ANIMAL CELL; ARTICLE; BLADDER CANCER; CELL SURVIVAL; CLONOGENESIS; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOBIOLOGY; RADIOSENSITIVITY;

ANIMALS; CARCINOMA, TRANSITIONAL CELL; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; RADIATION TOLERANCE; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0032959187     PISSN: 10657541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6823(1999)7:2<66::AID-ROI2>3.0.CO;2-T     Document Type: Article

References (59)

1. Gospodarowicz MK, Warde PR. A critical review of the role of definitive radiation therapy in bladder cancer. Semin Urol 1993;11:214-226.
2. Heppner GH. Tumor Heterogeneity. Cancer Res 1984; 44:2259-2265.
3. Suit H, Skates S, Taghian A, Okunieff P, Efird JT. Clinical implications of heterogeneity of tumor response to radiation therapy. Radiother Oncol 1992;25: 251-260.
4. Durand RA. The influence of microenvironmental factors during cancer therapy. In Vivo 1994;8:691-702.
5. Solberg TD, Holly FE, Desalles AA, Wallace RE, Smathers JB. Implications of tissue heterogeneity for radiosurgery in head and neck tumours. Int J Radiat Oncol Biol Phys 1995;32:235-239.
6. Courtenay VD. Radioresistant mutants of L5178Y cells. Radiat Res 1979;38:186-203.
7. Jeggo PA, Kemp LM. X-ray sensitive mutants of Chinese hamster ovary cell line: isolation and cross-sensitivity to other DNA-damaging agent. Mutat Res 1983;112:313-327.
8. McMillan TJ, Holmes A. The isolation and partial characterisation of a radiation-sensitive clone of a human bladder carcinoma cell line. Radiat Res 1991;128:301-305.
9. Allam A, Taghian A, Giosioso D, Duffy M, Suit HD. Intratumoral heterogeneity of malignant gliomas measured in vitro. Int J Radiat Oncol Biol Phys 1993;27: 303-308.
10. Buronfosse A, Thomas CP, Ginestet C, Dore JF. Radiosensitivity in vitro of clonogenic and non-clonogenic glioblastoma cells obtained from a human brain tumor. Life Sci 1994;317:1031-1041.
11. Powell S, McMillan TJ. Clonal variation of DNA repair in a human glioma cell line. Radiother Oncol 1991;21: 225-232.
12. Ramsay J, Ward R, Bleehen NM. Radiosensitivity testing of human malignant gliomas. Int J Radiat Oncol Biol Phys 1992;24:675-680.
13. Yang X, Darling JL, McMillan TJ, Peacock JH, Steel GG. Heterogeneity of radiosensitivity in a human glioma cell line. Int J Radiat Oncol Biol Phys 1992;22: 103-108.
14. Weichselbaum RR, Beckett MA, Dahlberg BS, Dritschilo A. Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones. Int J Radiat Oncol Biol Phys 1988;14:907-912.
15. Hill H, Hill JG, Miller CF, Kwong F, Purdy J. Radiation and melanoma, Response of B16 mouse tumor cells and clonal lines to in vitro irradiation. Radiat Res 1979;80:259-276.
16. Spruck CH, Ohneseit PF, Gonzalez-Zulueta M, Esrig D, Miyao N, Tasi YC, Lerner SP, Schmutte C, Yang AS, Cote R, Dubeau L, Nichols PW, Hermann GG, Steven K, Horn T, Skinner DG, Jones PA. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 1994;54:784-788.
17. Fijimoto K, Yamada Y, Okajima E, Kakizoe T, Sasaki H, Sugimura T. Frequent association of p53 gene mutation in invasive bladder cancer. Cancer Res 1992;52: 1393-1398.
18. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene, clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-4878.
19. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991;51:6304-6311.
20. Zhan Q, Bae I, Kastan MB, Fornace AJ Jr. The p53-dependent gamma-ray response of GADD45. Cancer Res 1994;54:2755-2760.
21. Siles E, Villalbos M, Valenzuela MT, Nunez MI, Gordon A, McMillan TJ, Pedraza V, Ruiz de Almodovar JM. Relationship between p53 status and radiosensitivity in human tumour cell lines. Br J Cancer 1996;3: 581-588.
22. Clarke AR, Gledhill S, Hooper ML, Bird CC, Wyllie A. p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogene 1994;9:1767-1773.
23. Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994;78: 703-711.
24. Lee JM, Bernstein A. p53 mutations increase resistance to ionising radiation. Proc Natl Acad Sci USA 1993; 90:5742-5746.
25. McIlwrath AJ, Vasey PA, Ross GM, Brow R. Cell cycle arrest and radiosensitivity of human tumor cell lines, dependence on wild-type p53 for radiosensitivity. Cancer Res 1994;54:3718-3722.
26. O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I, Kohn KW. Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res 1993;53:4776-4780.
27. Xia F, Wang Y-H, Tsang N-M, Yandell DW, Keltsey KT, Liber HL. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res 1995;55:12-15.
28. Brachman DG, Beckett M, Graves D, Haraf D, Vokes E, Weichselbaum RR. p53 mutation does not correlate with in 24 head and neck cancer cell lines. Cancer Res 1993;53:3667-3669.
29. Slichenmyer WJ, Nelson WG, Slebos RJ, Kastan MB. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res 1993;53:4164-4168.
30. Yu Y, Li C-Y, Little JB. Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblast cells. Oncogene 1997;14:1661-1667.
31. Ribeiro JCC, Barnetson AR, Fisher RJ, Mameghan H, Russell PJ. Radiation response and p53 status in human bladder cancer cell lines. Internat J Radiat Biol 1997; 72:11-20.
32. Mameghan H, Fisher R, Mameghan J, Brook S. Analysis of failure following definitive radiotherapy for invasive transitional cell carcinoma of the bladder. Int J Radiat Oncol Biol Phys 1995;31:247-254.
33. Raghavan D, Huben R. Management of bladder cancer. Curr Probl Cancer 1995;19:4-63.
34. Brown JL, Russell PJ, Philips J, Wotherspoon J, Raghavan D. Clonal analysis of a bladder cancer cell line: an experimental model of tumor heterogeneity. Br J Cancer 1990;61:369-376.
35. Russell PJ, Ho Shon I, Boniface GR, Izard ME, Philips J, Raghavan D, Walker KZ. Growth and metastasis of human bladder cancer xenografts in the bladder of nude rats: a model for intravesical radioimmunotherapy. Urol Res 1991;19:207-213.
36. Stadler WM, Sherman J, Bohlander SK, Roulston D, Dreyling M, Rukstalis D, Olapade OI. Homozygous deletions within chromosomal bands 9p21-22 in bladder cancer. Cancer Res 1994;54:2060-2063.
37. Carmichael J, Degraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res 1987;47:943-946.
38. Cross P, Marshall ES, Baguley BC, Finlay GJ, Matthews JHL, Wilson WR. Proliferative assays for the assessment of radiosensitivity of tumor cell lines using 96-well microcultures. Radiat Oncol Investigat 1994;1: 261-269.
39. Price P, McMillan TJ. Use of the tetrazolium assay in measuring the response of the human tumor cells to ionising radiation. Cancer Res 1990;50:1392-1396.
40. Hakkinen A-M, Laasonen A, Linnainmaa K, Mattson K, Pyrhonen S. Radiosensitivity of mesothelioma cell lines. Acta Oncol 1996;35:451-156.
41. Russell PJ, Jelbart M, Wills E, Singh S, Wass J, Wotherspoon J, Raghavan D. Establishment and characterisation of a new human bladder cancer cell line showing features of squamous and glandular differentiation. Int J Cancer 1988;41:74-82.
42. West CML, Sutherland RM. A radiobiological comparison of human tumor soft-agar clonogenic assays. Int J Cancer 1986;37:897-903.
43. Mosmann T. Rapid colorimetric assay for cellular growth and survival, application for proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
44. Brown JL, Lukeis R, Palavidis Z, Wass J, Raghavan D, Russell PJ. Karyotypic analysis of a heterogeneous human transitional cell carcinoma of the bladder. Cancer Genet Cytogenet 1994;72:116-125.
45. Raghavan D, Shipley WU, Garnick MB, Russell PJ, Richie JP. Biology and management of bladder cancer. N Engl J Med 1990;322:1129-1138.
46. Scholten AN, Leer JW, Collins CD, Wondergem J, Hermans J, Timothy A. Hyperfractionated radiotherapy for invasive bladder cancer. Radiother Oncol 1997;43: 163-169.
47. Slavotinek A, McMillan TJ, Steel CMG. Measurement of radiation survival using the MTT assay. Eur J Cancer 1994;30A:1376-1382.
48. Tannock I, Choo B, Buick R. The radiation response of human bladder cancer assessed in vitro or as xenografts in immune-deprived mice. Int J Radiat Oncol Biol Phys 1984;10:1897-1902.
49. Sinclair WK, Morton RA. X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells. Radiat Res 1966;29:450-474.
50. Ribeiro JCC, Hanley JR, Russell PJ. Studies of X-irradiated bladder cancer cell lines showing differences in p53 status, absence of a p53 cell cycle checkpoint pathway. Oncogene 1996;13:1269-1278.
51. Terasima T, Tolmach LJ. Variations in several responses of HeLa cells to x-irradiation during the cell cycle. Biophysics J 1963;3:11-33.
52. Withers HR, Mason K, Reid BO, Dubravsky N, Barkley TH Jr, Brown BW, Smathers JB. Response of mouse intestine to neutrons and gamma rays in relation to dose fractionation and division cycle. Cancer 1974; 34:39-47.
53. Powell SN, McMillan TJ. The repair fidelity of restriction enzyme-induced double-strand breaks in plasmid DNA correlates with radioresistance in human tumor cell lines. Int J Radiat Oncol Biol Phys 1994;29:1035-1040.
54. Ross GM, Eady JJ, Mithal NP, Bush C, Steel GG, Jeggo PA, McMillan TJ. DNA strand break rejoining defect in xrs-6 is complemented by transfection with the human Ku80 gene. Cancer Res 1995;55:1235-1238.
55. Joiner MC. Induced radioresistance, an overview and historical perspective. Int J Radiat Biol 1994;65:79-84.
56. McMillan TJ, Peacock JH. Molecular determinants of radiosensitivity in mammalian cells. Int J Radiat Biol 1994;65:49-55.
57. Powell SN, Whitaker SJ, Edwards SM, McMillan TJ. A DNA repair defect in a radiation-sensitive clone of a human bladder carcinoma cell line. Br J Cancer 1992; 65:798-802.
58. Zdzoemocla MZ, Vanwessel N, Vanderschans GP. A fourth complementation group among ionising radiation-sensitive Chinese hamster cell mutants defective in DNA double-strand break repair. Radiat Res 1992;131: 309-314.
59. Liu G, Lehnert S, Chow TYK. Mammalian endoexonuclease activity and its level in various radiation sensitive cell lines. Mutagenesis 1995;10:91-94.