In vivo insulin signaling in the myocardium of streptozotocin-diabetic rats: Opposite effects of diabetes on insulin stimulation of glycogen synthase and c-Fos

Endocrinology

Volumn 140, Issue 3, 1999, Pages 1141-1150

  Wang, Ping H ^a,c   Almahfouz, Abdulraof ^a,d   Giorgino, Francesco ^a,e   McCowen, Karen C ^a   Smith, Robert J ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b JOSLIN DIABETES CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^e UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; HEART MUSCLE; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; RAT; RNA ANALYSIS; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES;

EID: 0032958156     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.3.6595     Document Type: Article

References (48)

1. 1. Chain EB, Mansford KR, Opie LH 1969 Effects of insulin on the pattern of glucose metabolism in the perfused working and Langendorff heart of normal and insulin-deficient rats. Biochem J 115:537-546
2. 2. Katzen HM 1966 The effect of diabetes and insulin in vivo and in vitro on a low Km form of hexokinase from various rat tissues. Biochem Biophys Res Commun 24:531-536
3. 3. Miller Jr TB 1978 A dual role for insulin in the regulation of cardiac glycogen synthase. J Biol Chem 253:5389-5394
4. 4. Oliver MF, Opie LH 1994 Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias. Lancet 343:155-158
5. 5. Opie LH, Owen P, Riemersma RA 1973 Relative rates of oxidation of glucose and free fatty acids by ischaemic and non-ischaemic myocardium after coronary artery ligation in the dog. Eur J Clin Invest 3:419-435
6. 6. Avogaro A, Nosadini R, Doria A, Fioretto P, Velussi M, Vigorito C, Sacca L, Toffolo G, Cobelli C, Trevisan R 1990 Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am J Physiol 258:E606-E618
7. 7. Santora AC, Wheeler FB, DeHaan RL, Elsas LJ 1979 Relationship of insulin binding to amino acid transport by cultured 14-day embryonic chick heart cells. Endocrinology 104:1059-1068
8. 8. Wool IG, Rampersad OR, Moyer AN 1966 Effect of insulin and diabetes on protein synthesis by ribosomes from heart muscle. Significance for theories of the hormone's mechanism of action. Am J Med 40:716-723
9. 9. Morgan HE, Jefferson LS, Wolpert EB, Rannels DE 1971 Regulation of protein synthesis in heart muscle. II. Effect of amino acid levels and insulin on ribosomal aggregation. J Biol Chem 246:2163-2170
10. 10. Wildenthal K, Griffin EE, Ingwall JS 1976 Hormonal control of cardiac protein and amino acid balance. Circ Res [Suppl 1] 38:I138-I144
11. 11. Magri KA, Ewton DZ, Florini JR 1991 The role of the IGFs in myogenic differentiation. Adv Exp Med Biol 293:57-76
12. 12. Tornqvist HE, Pierce MW, Frackelton AR, Nemenoff RA, Avruch J 1987 Identification of insulin receptor tyrosine residues autophosphorylated in vitro. J Biol Chem 262:10212-10219
13. 13. Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF 1991 Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352:73-77
14. 14. Sun XJ, Wang L-M, Zhang Y, Yenush L, Myers Jr MG, Glasheen E, Lane WS, Pierce JH, White MF, Wang LM 1995 Role of IRS-2 in insulin and cytokine signalling. Nature 377:173-177
15. 15. Giorgetti S, Pelicci PG, Pelicci G, Van Obberghen E 1994 Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor. Eur J Biochem 223:195-202
16. 16. Lavan BE, Lane WS, Lienhard GE 1997 The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family. J Biol Chem 272:11439-11443
17. 17. Lavan BE, Fantin VR, Chang ET, Lane WS, Keller SR, Lienhard GE 1997 A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. J Biol Chem 272:21403-21407
18. 18. Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR 1994 Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
19. 19. Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA 1995 Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789
20. 20. Waters SB, Yamauchi K, Pessin JE 1993 Functional expression of insulin receptor substrate-1 is required for insulin-stimulated mitogenic signaling. J Biol Chem 268:22231-22234
21. 21. Kim SJ, Kahn CR 1994 Insulin stimulates phosphorylation of c-Jun, c-Fos, and Fos-related proteins in cultured adipocytes. J Biol Chem 269:11887-11892
22. 22. Izumo S, Nadal-Ginard B, Mahdavi V 1988 Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci USA 85:339-343
23. 23. Bauer EP, Kuki S, Arras M, Zimmerman R, Schaper W 1997 Increased growth factor transcription after pulmonary artery banding. Eur J Cardiothorac Surg 11:818-823
24. 24. Le Marchand-Brustel Y, Freychet P 1979 Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle. J Clin Invest 64:1505-1515
25. 25. Dall'Aglio E, Chang H, Hollenbeck CB, Mondon CE, Sims C, Reaven GM 1985 In vivo and in vitro resistance to maximal insulin-stimulated glucose disposal in insulin deficiency. Am J Physiol 249:E312-E316
26. 26. Giorgino F, Chen JH, Smith RJ 1992 Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: effects of insulin and glucose. Endocrinology 130:1433-1444
27. 27. Saad MJ, Araki E, Miralpeix M, Rothenberg PL, White MF, Kahn CR 1992 Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J Clin Invest 90:1839-1849
28. 28. Garvey WT, Hardin D, Juhaszova M, Dominguez JH 1993 Effects of diabetes on myocardial glucose transport system in rats: implications for diabetic cardiomyopathy. Am J Physiol 264:H837-H844
29. 29. Popovich BK, Sayen MR, Dillmann WH 1991 Insulin responsiveness of CK-M and CK-B mRNA in the diabetic rat heart. Am J Physiol 261:E377-E381
30. 30. Giorgino F, Smith RJ 1995 Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation: role of specific intracellular signaling pathways. J Clin Invest 96:1473-1483
31. 31. Ruderman NB, Kapeller R, White MF, Cantley LC 1990 Activation of phosphatidylinositol 3-kinase by insulin. Proc Natl Acad Sci USA 87:1411-1415
32. 32. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
33. 33. Pellici G, Lanfrancone L, Grignani F, McGlade, J, Cavallo F, Forni G, Nicoletti I, Pawson T, Pellici PG 1992 A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 70:93-104
34. 34. Wilden PA, Kahn CR, Siddle K, White MF 1992 Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function. J Biol Chem 267:16660-16668
35. 35. Karnieli E, Hissin PJ, Simpson IA, Salans LB, Cushman SW 1981 A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems. J Clin Invest 68:811-814
36. 36. Narimiya M, Chang H, Azhar S, Reaven GM 1984 Amelioration of streptozotocin-induced diabetes in the rat by exercise-training: role of muscle glycogenolytic and glycolytic enzyme activity. Horm Metab Res 16(Suppl 1):67-70
37. 37. Wilden PA, Siddle K, Haring E, Backer JM, White MF, Kahn CR 1992 The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies. J Biol Chem 267:13719-13727
38. 38. Olson AL, Pessin JE 1994 Regulation of c-fos expression in adipose and muscle tissue of diabetic rats. Endocrinology 134:271-276
39. 39. Flier JS, Moller DE, Moses AC, O'Rahilly S, Chaiken RL, Grigorescu F, Elahi D, Kahn BB, Weinreb JE, Eastman R 1993 Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance. J Clin Endocrinol Metab 76:1533-1541
40. 40. Myers Jr MG, White MF 1993 The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650
41. 41. Lisato G, Cusin I, Tiengo A, Del Prato S, Jeanrenaud B 1992 The contribution of hyperglycaemia and hypoinsulinaemia to the insulin resistance of streptozotocin-diabetic rats. Diabetologia 35:310-315
42. 42. Garcia MJ, McNamara PM, Gordon T, Kannel WB 1974 Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes 23:105-111
43. 43. Abbott RD, Donahue RP, Kannel WB, Wilson PW 1988 The impact of diabetes on survival following myocardial infarction in men vs women. The Framingham Study [published erratum appears in JAMA 1989 261:1884]. JAMA 260:3456-3460
44. 44. Sutherland CG, Fisher BM, Frier BM, Dargie HJ, More IA, Lindop GB 1989 Endomyocardial biopsy pathology in insulin-dependent diabetic patients with abnormal ventricular function. Histopathology 14:593-602
45. 45. Fein FS 1990 Diabetic cardiomyopathy. Diabetes Care 13:1169-1179
46. 46. Jackson T, Allard MF, Sreenan CM, Doss LK, Bishop SP, Swain JL 1990 The c-myc proto-oncogene regulates cardiac development in transgenic mice. Mol Cell Biol 10:3709-3716
47. 47. Dillmann WH 1980 Diabetes mellitus induces changes in cardiac myosin of the rat. Diabetes 29:579-582
48. 48. Ganguly PK, Pierce GN, Dhalla KS, Dhalla NS 1983 Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathy. Am J Physiol 244: E528-E535