Detrusor instability in the female: Controversies in diagnosis, etiology, and management

Critical Reviews in Physical and Rehabilitation Medicine

Volumn 11, Issue 1, 1999, Pages 35-61

  Moore, Kate H ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST GEORGE HOSPITAL   (Australia)

Author keywords

Age related incidence; Detrusor overactivity; Neuropeptides; Pharmacotherapy; Urodynamic studies

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; IMIPRAMINE; OXYBUTYNIN; PROPANTHELINE BROMIDE;

CYSTOMETRY; DETRUSOR DYSSYNERGIA; ELECTROSTIMULATION THERAPY; FEMALE; HUMAN; NOCTURIA; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; URGE INCONTINENCE; URODYNAMICS;

EID: 0032957951     PISSN: 08962960     EISSN: None     Source Type: Journal    
DOI: 10.1615/critrevphysrehabilmed.v11.i1.20     Document Type: Review

References (202)

1. Abrams, P. H., The Investigation of Bladder Outflow Obstruction in the Male, M.D. Thesis, University of Bristol, 1977, 77.
2. Abrams, P. H., Blaivas, J. G., Stanton, S. L., and Andersen, J. T., The standardization of terminology of lower urinary tract function, Scand. J. Urol. Nephrol., (Suppl.) 144, 5-19, 1988.
3. Abrams, P. H., Feneley, R. C. L., and Torrens, M., (1983a) Urodynamic investigations, in Urodynamics, Chapter 3, Springer Verlag, Heidelberg, 1983a, 28-29.
4. Abrams, P. H., Feneley, R. C. L., and Torrens, M., (1983b) The clinical contribution of urodynamics. In Urodynamics, Chapter 5, p.119. Heidelberg: Springer Verlag.
5. Abrams, P., Feneley, R., and Torrens, M., Urodynamics, 1st edition, Springer Verlag, Berlin, 1983c.
6. Abrams, P., Urodynamics, 2nd edition, Springer Verlag, London, 1997, 20-39.
7. Abrams, P. and Wein, A. K., Eds., The overactive bladder: from basic science to clinical management consensus conference, Urology, 50, Suppl. 6A, 1997.
8. Abrams, P., Freeman, R., Anderstrom, C., and Mattiasson, A., Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder, Br. J. Urol., 81, 801-810, 1998.
9. Al Taher, H., Sutherst J. R., Richmond, D. H., and Brown, M. C., Vaginal pressure during urodynamic evaluation, Br. J. Urol., 59, 529-532, 1987.
10. Anderson, J. T., Bladder function in healthy elderly males, Scand. J. Urol. Nephrol., 12, 123-127, 1978.
11. Andrew, J. and Nathan, P. W., Lesions of the anterior frontal lobes and disturbances of micturition and defecation, Brain, 87, 233-262, 1964.
12. Arnold, E. P., Cystometry. Postural effects in incontinent women, Urol. Int., 29, 185-186, 1974.
13. Bagley, N. A., Edward, J., and O'Shaughnessy, S., Urodynamic evaluation of voluntary detrusor response in healthy subjects, Arch. Phys. Med. Rehab., 66, 160-163, 1985.
14. Bakwin, H., Enuresis in twine, Am. J. Dis. Child., 121, 222-225, 1971.
15. Barer, D. H., Continence after stroke: useful predictor or goal of therpy? Age Ageing, 18, 183-191, 1989.
16. Bates, C. P., Whiteside C. G., and Turner-Warwick, R., Synchronous cine/pressure/flow/cystourethrography, with special reference to stress and urge incontinence, Br. J. Urol., 42, 714-723, 1970.
17. Bates, C. P., Continence and incontinence, Ann, Roy. Coll. Surg. Engl., 49, 18-35, 1971.
18. Beck, R. P., Thomas, E. A., and Maughan, G. B., The detrusor muscle and urinary incontinence, Am. J. Obstets. Gynecol., 94, 483-489, 1965.
19. Biswas, N. C., A silastic vaginal device for the treatment of stress urinary incontinence, Neurourol. Urodyn., 7, 271-272, 1988.
20. Blaivas, J. G., Management of bladder dysfunction in multiple sclerosis, Neurology, 30, 12-18, 1980.
21. Blok, B. F. M., Willemsen, A. T. M., and Holstege, B., A PET study on brain control of micturition in humans, Brain, 120: 111-121, 1997.
22. Boedker, A., Lendorf, A., H-Nielsen, A., and Glahn, B., Micturition pattern assessed by frequency volume chart in a healthy population of men and women, Neurourol. Urodyn., 8, 421-422, 1989.
23. Booth, C. M., Milroy, E. G., Whiteside, C. G., and Turner-Warwick, R. T., A long-term study of the urodynamics of the untreated unstable bladder. Proc. XIth I.C.S. Meeting, Los Angeles, in Female Incontinence, Liss, New York, 1981, 205-210.
24. Bosch, R. and Growen, J., Seven years of experience with sacral (S3) segmental nerve stimulation in patients with urge incontinence due to detrusor instability or hyperreflexia, Neurourol. Urodyn., 16, 426-427, 1997.
25. Bower, W. F., Moore, K. H., Adams, R. D. and Shepherd, R. B., A urodynamic study of surface neuromodulation versus sham in detrusor instability and sensory urgency, J. Urol., 106, 2133-2136, 1998.
26. Brading, A. F. and Turner, W. H., The unstable bladder: towards a common mechanism, Br. J. Urol., 73, 3-8, 1994.
27. Brading, A. F., A myogenic basis for the overactive bladder, Urology, 50, (Suppl. 6A), 57-67, 1997.
28. Bramble, F. J., The treatment of adult eneuresis and urge incontinence by enterocystoplasty, Br. J. Urol., 54, 693-696, 1982.
29. Bryant, C. M., Dowell, C. J., and Moore, K. H., How much does incontinence really cost? Neurourol. Urodyn., 16, 460-461, 1997.
30. Brocklehurst, J. C. and Dillane, J. B., Studies of the female bladder in old age. I. Cystometrograms in nonincontinent women, Gerontol. Clinics, 8, 285-305, 1966.
31. Burton, G., A randomized cross over trial comparing oxybutynin taken three times a day or taken "when needed", Neurourol. Urodyn., 13, 351-352, 1994.
32. Cardozo, L. D., Abrams, P. H., Stanton, S. L., and Feneley, R. C. L., Idiopathic detrusor instability treated by biofeedback, Br. J. Urol., 50, 521-523, 1978.
33. Cardozo, L. D., Stanton, S. L., and Williams, J. E., Detrusor instability following surgery for genuine stress incontinence, Br. J. Urol., 51, 204-207, 1979.
34. Cardozo, L., Rekers, H., Tapp, A., et al., Oestriol in the treatment of postmenopausal urgency: a multicentre study, Maturitas, 18, 47-53, 1993.
35. Castleden, C. M., Duffin, H. M., and Gulati, R. S., Double-blind study of imiprarnine and placebo for incontinence due to bladder instability, Age Ageing, 15, 299-303, 1986.
36. Chancellor, M. B., Kaplan, S. A., and Blaivas, J. G., Detrusor-external sphincter dyssynergia, in Neurobiology of Incontinence, Ciba Foundation Symposium 151, Bock, G. and J Whelan, J., Eds., John Wiley & Sons, New York, 1990, 195-222.
37. Collas, D. and Malone-Lee, J. G., The pharmacokinetic properties of rectal oxybutynin; a possible alternative to intravesical administration, Neurourol. Urodyn., 16, 346-347, 1997.
38. Coolsaet, B., Bladder compliance and detrusor activity during the collecting phase, Neurourol. Urodyn., 4, 263-265, 1985.
39. De Groat, W. C., A neurologic basis for the overactive bladder, Urology, 50 (Supple. 6A), 36-56, 1997.
40. Daniel, E. E., Cowan, W., and Daniel, V. P., Structural basis for neural and myogenic control of human detrusor, Can. J. Physiol. Pharmacol., 61, 1247-1273, 1983.
41. Delaere, K. P., Debruyne, F. M., Michiels, H., and Moonen, W., Prolonged bladder distension in the management of the unstable bladder, J. Urol., 124, 334-336, 1980.
42. Diokno, A. C., Brock, B. M., Brown, M. B., and Herzog, A. R., Prevalence of urinary incontinence and other urological symptoms in the noninstitutionalized elderly, J. Urol., 136, 1022-1025, 1986.
43. Diokno, A. C., Brown, B. M., Brock, B. M., Herzog, A. R., and Nordle, D. P., Clinical and cystometric characteristics of continent and incontinent noninstutionalized elderly, J. Urol., 140, 567-571, 1988.
44. Dunn, M., Prolonged bladder distension as a treatment of urgency and urge incontinence of urine, Br. J. Urol., 46, 645-652, 1974.
45. Dunn, N., Prolonged bladder distension as a treatment of urgency and urge incontinence of urine. Br. J. Urol., 46, 645-652, 1974b.
46. Elbadawi, A., Neuromorphologic basis of vesicourethral function: I. Histochemistry, ultrastructure, and function of the intrinsic nerves of the bladder and urethra, Neurourol. Urodyn., 1, 3-50, 1982.
47. Elbadawi, A., Hailemariam, S., Yalla, S. V., and Resnick, N. M., Structural basis of geriatric voiding dysfunction. VI. Validation and update of diagnostic criteria in 71 detrusor biopsies, J. Urol., 157, 1802-1813, 1997.
48. Essenhigh, D. M. and Yates, W. K., Transection of the bladder with particular reference to enuresis, Br. J. Urol., 45, 299-305, 1973.
49. Fall, M. and Lindstrom, S., Electrical stimulation: a physiological approach to the treatment of urinary incontinence, Urol. Clin. N. Am., 18, 393-407, 1991.
50. Fitzmaurice, H., Fowler, C. J., Rickards, D., Kirby, R. S., Quinn, N. P., Marsden, C. D., Milroy, E. J. G., and Turner-Warwick, R. T., Micturition disturbance in Parkinson's disease, Br. J. Urol., 57, 652-656, 1985.
51. Fitzpatrick, J. M., Gardiner, R. A., and Worth, P. H. L., The evaluation of 68 patients with post-prostatectomy incontinence, Br. J. Urol., 51, 552-555, 1979.
52. Fonda, D., Brimage, P. J., and D'Astoli, Simple screening for urinary incontinence in the elderly: comparison of simple and multi-channel cystometry, Urology, 42, 536-540, 1984.
53. Fossberg, E., Sorensen, S., Ruutu, M., Bakke, A., Stien, R., Henriksson, L., and Kinn, A. C., Maximal electrical stimulation in the treatment of unstable detrusor and urge incontinence, Eur. Urol., 18, 120-123, 1990.
54. Fowler, C. J., Beck, R. O., Betts, C. D., Lynn, B., and Fowler, C. G., Intravesical capsaicin for treatment of detrusor hyperreflexia, Neurourol. Urodyn., 11, 107-108, 1992.
55. Frary, L. G., Enuresis, a genetic study, Am. J. Dis. Child., 49, 557-578, 1935.
56. Frewen, W. K., An objective assessment of the unstable bladder of psychosomatic origin, Br. J. Urol., 50, 246-249, 1978.
57. Frimodt-Moller, C., A urodynamic study of micturition in healthy men and women, Dan. Med. Bull., 21, 41-48, 1974.
58. Fry, C. H., Cellular physiology of detrusor smooth muscle and the development of bladder instability: possible mechanisms, Urology, 50 (Supple. 6A), 70-71, 1997.
59. Gibbon, N. O. K., Jameson, R. M., Heal, M. R., and Abel, B. J., Transection of the bladder for adult enuresis and allied conditions, Br. J. Urol., 45, 306-309, 1973.
60. Gilpin, S. A., Gosling, J. A., and Barnard, R. J., Morphological and morphometric studies of the human obstructed, trabeculated urinary bladder, Br. J. Urol., 56, 525-529, 1985.
61. Gosling, J. A. and Dixon, J. S., Sensory nerves in the mammalian urinary tract. An evaluation using light and electron microscopy, J. Anat., 117, 133-144, 1974.
62. Gosling, J. A., Dison, J. S., and Dunn, M., The structure of the rabbit urinary bladder following experimental distension, Invest. Urol., 14, 386-389, 1976.
63. Griffiths, D. J., McCracken, P. N., and Harrison, G. M., Incontinence in the elderly: objective demonstration and quantitative assessment, Br. J. Urol., 67, 467-471, 1991.
64. Griffiths, D. J., McCracken, P. N., Harrison, G. M., and Gormley, E. A., Characteristics of urinary incontinence in elderly patients studied by 24 hour monitoring and urodynamic testing, Age Ageing, 21, 195-201, 1992.
65. Griffiths, D. J., McCracken, P. N., Harrison, G. M., Gormley, E. A., Moore, K., Hooper, R., McEwan, A. J. B., and Triscott, J., Cerebral etiology of urinary urge incontinence in elderly people, Age Ageing, 23, 246-250, 1994.
66. Grunewald, V. and Jonas, U., Neurologic abnormalities, in The Bladder, Fitzpatrick, J. M. and Krane, R. J., Eds., Churchill Livingstone, Edinburgh, Chap. 13, 1995, 195-212.
67. Gu, J., Restorick, J. M., Blank, M. A., Huang, W. M., Polak, J. M., Bloom, S. R., and Mundy, A. R., Vasoactive intestinal polypeptide in the normal and unstable bladder, Br. J. Urol., 55, 645-647, 1983.
68. Harrison, S. C., Hunnam, G. R., Farman, P., Ferguson, D. R., and Doyle, P. T., Bladder instability and denervation in patients with bladder outflow obstruction, Br. J. Urol., 519-522, 1987.
69. Hasan, S. T., Robson, W. A., Pridie, A. K., and Neal, D. E., Outcome of transcutaneous electrical stimulation in patients with detrusor instability, Neurourol. Urodyn., 13, 349-350, 1994.
70. Haylen, B. T., Ashby, D., Sutherst, J. R., Frazer, M. I., and West, C. R., Maximum and average urine flow rates in normal male and female populations - The Liverpool Nomograms, Br. J. Urol., 64, 30-38, 1989.
71. Herbert, D. B. and Ostergard, D. R., Urethral instability. Obstet. Gynecol., 60, 331-337, 60, 331-337, 1982.
72. Heslington, K. and Hilton, P., Ambulatory urodynamic monitoring, Br. J. Obstet. Gynecol., 103, 393-399, 1996.
73. Higson, R. H., Smith, J. C., and Whelan, P., Bladder rupture: an acceptable complication of distension therapy? Br. J. Urol., 50, 529-534, 1978.
74. Hilton, P., Urinary incontinence in women, Br. Med. J., 295, 426-432, 1987.
75. Hilton, P., Urinary incontinence during sexual intercourse: a common, but rarely volounteered symptom, Br. J. Obstet. Gynecol., 95, 377-381, 1988.
76. Hilton, P. and Stanton, S. L., Algorithmic method for assessing urinary incontinence in elderly women, Br. Med. J., 282, 940-942, 1981.
77. Hindmarsh, J. R., Essenhigh, D. M., and Yeates, K. W., Bladder transection for adult enuresis, Br. J. Urol., 49, 515-521, 1977b.
78. Hodgkinson, C. P., Ayers, M. A., and Drukker, B. H., Dyssynergic detrusor dysfunction in the apparently normal female, Am. J. Obstet. Gynecol., 87, 717-728, 1973.
79. Holmes, D. M., Stone, A. R., Bary, P. R., Richards, C. J., and Stephenson, T. P., Bladder training - 3 years on, Br. J. Urol., 55, 660-664, 1983.
80. Holmes, D. M., Montz, F. J., and Stanton, S. L., Oxybutynin versus propantheline in the management of detrusor instability. A patient regulated variable dose trial, Br. J. Obstets. Gynecol., 96, 607-612, 1989.
81. Iosif, C., Batra, S., Ek, A., and Astedt, B., Estrogen receptors in the human female lower urinary tract, Am. J. Obstet. Gynecol., 141, 817-820, 1981.
82. Iosef, C. S. and Bekassy, Z., Prevalence of genito-urinary symptoms in the later menopaus, Acta Obstet. Gynecol. Scand., 63, 257-260, 1984.
83. Janknegt, R. A., Noonen, W. A., and Schreinemachers, L. M. H., Transection of the bladder as a method of treatment in adult enuresis nocturna, Br. J. Urol., 51, 275-277, 1979.
84. Jarvis, G. J. and Millar, D. R., Controlled trial of bladder drill for detrusor instability, Br. Med. J., 281, 1322-1323, 1980.
85. Jarvis, G. J., A controlled trial of bladder drill and drug therapy in the management of detrusor instability, Br. J. Urol., 53, 565-566, 1981.
86. Jarvis, G. J., The management of urinary incontinence due to primary vesical sensory urgency by bladder drill, Br. J. Urol., 54, 374-376, 1982.
87. Jeffcoate, T. N. A. and Francis, W. J., Urgency incontinence in the female, Am. J. Obstet. Gynecol., 94, 604-618, 1966.
88. Jones, K. W. and Schoenberg, H. W., Comparison of the incidence of bladder hyperreflexia in patients with benign prostatic hypertrophy and age-matched female controls, J. Urol., 133, 425-426, 1985.
89. Kelleher, C. J., Cardozo, L. D., Khullar, V., and Salvatore, S., A medium term analysis of the subjective efficacy of treatment for women with detrusor instability and low bladder compliance, Br. J. Obstets. Gynae., 104, 988-993, 1997.
90. Kennelly, M. J., Gormley, E. A., and McGuire, E. J., Early clinical experience with adult bladder autoaugmentation, J. Urol., 152, 303-306, 1994.
91. Kinder, R. B. and Mundy, A. R., Inhibition of spontaneous contractile activity in isolated human detrusor muscle strips by vasoactive intestinal polypeptide, Br. J. Urol., 57, 20-23, 1985a.
92. Kinder, R. B. and Mundy A. R., Atropine blockade of nerve mediated stimulation of the human detrusor, Br. J. Urol., 57, 418-421, 1985b.
93. Kinder, R. B. and Mundy, A. R., Pathophysiology of idiopathic detrusor instability and detrusor hyperreflexia, Br. J. Urol., 60, 509-515, 1987.
94. Kinder, R. B., Restorick, J. M., and Mundy, A. R., Vasoactive intestinal polypeptide in the hyperreflexic neuropathic bladder, Br. J. Urol., 57, 289-291, 1985.
95. Kirby, R. S., Urethro-vesical dysfunction in autonomic neuropathy, M.D. Thesis, University of London, 1985, 58, 202.
96. Klarskov, P., Enkephalin inhibits presynaptically the contractility of urinary tract smooth muscle, Br. J. Urol., 59, 31-35, 1987.
97. Klarskov, P. and Hald, T., Reproducibility and reliability of urinary incontinence assessment with a 60 min test, Scand. J. Urol. Nephrol., 18, 293-298, 1984.
98. Kondo, A., Kato, K., Saito, M., and Otani, T., Prevalence of hand-washing urinary incontinence in females in comparison with stress and urge incontinence, Neurourol. Urodyn., 9, 330-331, 1990.
99. Kuchel, G. A. and Resnick, N. M., Does estrogen deficiency contribute to impaired bladder contractility in older women? Neurourol. Urodyn., 16, 443-444, 1997.
100. Larsson, G., Abrams, P., and Victor, A., The frequency volume chart in detrusor instability, Neurourol. Urodyn., 10, 535-543, 1991.
101. Laycock, J., Clinical evaluation of the pelvic floor, in Pelvic Floore Reeducation, Principles, and Practice, Schussler, B., Laycock, J., Norton, P., and Stanton, S., Eds., Springer, London, 1994, 42-48.
102. Lewis, D. K., Morgan, J. R., Weston, P. M. T., and Stephenson, T. P., The "clam": indication and complications, Br. J. Urol., 65, 488-491, 1990.
103. Lloyd, S. N., Lloyd, S. M., Rogers, K., Deane, R. F., Kirk, D., and Lyle, K. F., Is there still a place for prolonged bladder distension? Br. J. Urol., 70, 382-386, 1992.
104. Lockhart, J. L., Webster, G. D., Sheremeta, W., Camuzzi, F. A., and Carrion, H. C., Heurogenic bladder dysfunction in the Shy-Drager syndrome, J. Urol., 126, 119-121, 1981.
105. Macauley, A. J., Stern, R. S., Holmes, D. M., and Stanton, S. L., Micturition and the mind: pychological factors in the etiology and treatment of urinary symptoms in women, Br. Med. J., 294, 540-543, 1987.
106. Mahady, I. W. and Begg, B. M., Long term symptomatic and cystometric cure of the urge incontinence syndrome using a technique of bladder reeducation, Br. J. Obstet. Gynecol., 88, 1038-1043, 1981.
107. Malone-Lee, J. G. and Wiseman, P., Detrusor function in Parkinson's disease, Neurourol. Urodyn., 10, 355-356, 1991.
108. Malone-Lee, J. G., A reexamination of detrusor hyperactively with impaired contractile function, Neurourol. Urodyn., 11, 298-300, 1992.
109. Mayo, M. E., Detrusor hyperreflexia: the effect of posture and pelvic floor activity, J. Urol., 119, 635-638, 1978.
110. Mayo, M. E. and Burns, M. W., Urodynamic studies in children who wet, Br. J. Urol., 65, 641-645, 1990.
111. Merrill, D. C., Bradley, W. E., and Markland, C., Air cystometry II: a clinical evaluation of normal adults, J. Urol., 108, 85-88, 1972.
112. Millard, R. J. and Oldenburg, B. F., The symptomatic, urodynamic, and psychodynamic results of bladder reeducation programs, J. Urol., 130, 715-719, 1983.
113. Millard, R. J., Moore, K. H., Dwyer, D., and Tuttle, D., Clinical and urodynamic efficacy of Tolterodine: a multicenter placebo-controlled trial, Neurourol. Urodyn., 16, 343-344, 1997.
114. Moore, K. H., Hay, D. M., Imrie, A. H., Watson, A., and Goldstein, M., Oxybutynin chloride (3 mg) in the treatment of women with idiopathic detrusor instability, Br. J. Urol., 66, 479-485, 1990a.
115. Moore, K. H. and Sutherst, J. R., Response to treatment of detrusor instability in relation to psychoneurotic status, Br. J. Urol., 66, 486-490, 1990b.
116. Moore, K. H., Skehan, M., Richmond, D. H., Sutherst, J. R., and Barer, D., The value of urodynamic evaluation in elderly mobile women, Proc. Roy. Aust. N.Z. Coll. Obstets. Gynaecol. Ann. Cong., Queenstown, New Zealand, 1991a.
117. Moore, K. H, Richmond, D. H., and Parys, B., Sex distribution of adult idiopathic detrusor instability in relation to childhood bedwetting, Br. J. Urol., 68, 479-482, 1991b.
118. Moore, K. H., Richmond, D. H., Sutherst, J. R., Imrie, A. I., and Hutton, J. L., Crouching over the toilet seat: prevalence among British gynecological outpatients and its effect upon micturition, Br. J. Obstet. Gynaecol., 98, 569-572, 1991c.
119. Moore, K. H., Vaillant, C., Nemeth, J., Richmond, D. H, and Sutherst, J. R., Vasoactive intestinal polypeptide (VIP) in refractory detrusor instability, Neurourol. Urodyn., 10, 330-331, 1991d.
120. Moore, K. H., Richmond, D. H., Sutherst, J. R., and Manasse, P., Is severe "wetness" associated with severe "madness" in detrusor instability? Neurourol. Urodyn., 11, 460-461, 1992a.
121. Moore, K. H., Gilpin, S., Dixon, J. S., Richmond, D. H., and Sutherst, J. R., An increase of presumptive sensory nerves of the urinary bladder in idiopathic detrusor instability, Br. J. Urol., 70, 370-372, 1992b.
122. Moore, K. H., Richmond, D. H., Sutherst, J. R., and Manasse, P. R., "One-shot" biofeedback in relation to psychoneurotic status and treatment response in detrusor instability, Neurourol. Urodyn., 11, 365-366, 1992c.
123. Moore, K. H., Idiopathic detrusor instability in women: the psyche and the soma, M.D. thesis, University of Liverpool, Merseyside, U.K., 1994.
124. Moore, K. H., Foote, A. J., Siva, S., King, J., and Burton, G., The use of the bladder neck support prosthesis in combined genuine stress incontinence and detrusor instability, Australian N. Zealand J. Obstet. Gynecol., 1997, 37, 440-445.
125. Moore, K. H., Foote, A. J., Burton, G., and King, J., An open study of the bladder neck support prosthesis in genuine stress incontinence, Br. J. Obstet. Gynecol., in press, 1999.
126. Mostwin, J. L, Karim, O. M., van Koeveringe, G., and Brooks, E. L., The guinea pig as a model of gradual urethral obstruction, J. Urol., 145, 854-858, 1991.
127. Mostwin, J. L., Effects of urethral obstruction on guinea pig bladder muscle, Urology, 50 (Suppl. 6A), 6870, 1997.
128. Mundy, A. R., Bladder transection for urge incontinence associated with detrusor instability, Br. J. Urol., 52, 480-483, 1980.
129. Mundy, A. R., Surgical treatment of urge incontinence of urine, J. Urol., 128, 481-483, 1982.
130. Mundy, A. R., Long-term results of bladder transection for urge incontinence, Br. J. Urol., 55, 642-644, 1983.
131. Mundy, A. R. and Stephenson, T. P., Clam ileocystoplasty for the treatment of refractory urge incontinence, Br. J. Urol., 57, 641-646, 1985.
132. Mundy, A. R., Stephenson, T. P., and Wein, A. J., Urodynamics: Principles, Practice, and Application, chap. 8-9, Churchill Livingstone, Edinburgh, 1994, 101-132.
133. Norton, K. R. W., Bhat, A. V., and Stanton, S. L., Psychiatric aspects of urinary incontinence in women attending an outpatient urodynamic clinic, Br. Med. J., 301, 271-272, 1990.
134. Palnaes Hansen, C. and Klarskov, P., The accuracy of the frequency volume chart; comparison of self-reported and measure volumes, Br. J. Urol., 81, 709-711, 1998.
135. Parkin, D. E., Davis, J. A., and Symonds, R. P., Urodynamic findings following radiotherapy for cervical carcinoma, Br. J. Urol., 61, 213-217, 1988.
136. Parsons, K. F., O'Boyle, P. J., and Gibbons, N. O. K., A further assessment of bladder transection in the management of adult enuresis and allied conditions, Br. J. Urol., 49, 509-514, 1977.
137. Parsons, K. F., Machin, D. G., Woolfendon, K. A., Walmsley, B., Abercrombie, G. F., and Vinnicombe, B., Endoscopic bladder transection, Br. J. Urol., 56, 625-628, 1984.
138. Parys, B. T., Haylen, B. T., Hutton, J. L., and Parsons, K. F., The effects of simple hysterectomy on vesicourethral function, Br. J. Urol., 64, 594-599, 1989.
139. Peattie, A. B., (1990) The management of sensory urgency, in Micturition, chapt. 19, Drife, J. O., Hilton, P., and Stanton, S. L., Eds., Springer-Verlag, Berlin, 1990, 315-332.
140. Pengelly, A. W., Stephenson, T. P., Milroy, E. J. C., Whiteside, C. G, and Turner-Warwick, R., Results of prolonged bladder distension as a treatment for detrusor instability, Br. J. Urol., 50, 243-245, 1978.
141. Pengelly, A. W. and Booth, C. M., A prospective trial of bladder training as treatment for detrusor instability, Br. J. Urol., 52, 463-466, 1980.
142. Prashar, S., Moore, K. H., Anderson, P., Louey, M., Cragg, S., Simons, A. M., and Foote, A. J., A randomized controlled trial of nurse continence advisor management versus urogynecology management of conservative continence therapy: benefits and costs, Neurourol. Urodyn., 17, 423-424, 1998.
143. Ramsden, P. D., Smith, J. C., Dunn, M., and Ardran, G. M., Distension therapy for the unstable bladder: later results including an assessment of repeat distensions, Br. J. Urol., 48, 623-629, 1976.
144. Rentzhog, L., Stanton, S. L., Cardozo, L., Nelson, E., Fall, M., and Abrams, P., Efficacy and safety of tolterodine in patients with detrusor instability: a dose-ranging study, Br. J. Urol., 81, 42-48, 1998.
145. Resnick, N. M., Subbarao, V., and Yalla, S. V., Detrusor hyperactivity with impaired contractile function. An unrecognized but common cause of incontinence in elderly patients, JAMA, 257, 3076-3081, 1987
146. Resnick, N. M., Yalla, S. V., and Laurino, E., The pathophysiology of urinary incontinence among institutionlized elderly persons, N. Engl. J. Med., 320, 1-7, 1989.
147. Richardson, D. A., Bent, A. K., and Ostergard, D. R., The effect of utero-vaginal prolapse on urethrovesical pressure dynamics, Am. J. Obstet. Gynecol., 146, 901-905, 1983.
148. Samsioe, G., Jansson, I., Mellstrom, D., and Svangorg, A., Urinary incontinence in 75 year old women: effects of estriol, Acta Obstet. Gynecol. Scand., 93, 57, 1980.
149. Sand, P. K., Hill, R. C., and Ostergard, D. R., Supine urethroscopic and standing cystometry as screening methods for the detection of detrusor instability, Obstet. Gynecol., 70, 57-60, 1987.
150. Sand, P. K., Hill, R. C., and Ostergard, D. O., Incontinence history as a predictor of detrusor instability, Obstet. Gynecol., 71, 257-260, 1988.
151. Schmidt, R. A., Applications of neurostimulation in urology, Neurourol. Urodyn., 7, 585-586, 1988.
152. Seki, N., Karim, O. M., Mostwin, J. L., Changes in action potential kinetics following experimental bladder outflow obstruction in the guinea pig, Urol. Res., 20, 387-392, 1992.
153. Sethia, K. K., Webb, R. J., and Neal, D. E., Urodynamic study of ileocystoplasty in the treatment of idiopathic detrusor instability, Br. J. Urol., 67, 286-290, 1991.
154. Smet, P., Moore, K. H., Jonavicius, J., and Lynch, W., Immunohistochemical localization of nerves containing sensory neuropeptides in idiopathic unstable and normal human bladder, Neurourol. Urodyn., 14, 514-516, 1995.
155. Sorensen, S., Knudsen, U. B., Kirkeby, H. J., and Djhurhuus, J. C., Urodynamic investigations in healthy fertile females during the menstrual cycles, Scand. J. Urol. Nephrol. Suppl., 114, 28-34, 1988.
156. Speakman, M. J., Brading, A. F., Gilpin, C. J., Dixon, J. S., Gilpin, S. A., and Gosling, J. A., Bladder outflow obstruction - cause of denervation supersensitivity, J. Urol., 138, 1461-1466, 1987.
157. Stanton, S. L., Clinical Gynecologic Urology, Mosby, St. Louis, 1984.
158. Staskin, F. R., Parsons, K. F., Levin, R. M., and Wein, A. J., Bladder transection: a functional, neurophysiological, neuropharmacological, and neuroanatomical study, Br. J. Urol., 53, 552-557, 1981.
159. Steers, W. D., Kolbeck, S., Creedon, D., and Tuttle, J. B., Nerve growth factor in the urinary bladder of the adult regulates neuronal form and function, J. Clin. Invest., 88, 1709-1715, 1991.
160. Steers, W. D., Creedon, D., and Tuttle, J. B., Immunity to NGF prevents afferent plasticity following hypertrophy of the urinary bladder, J. Urol., 155, 378-385, 1996.
161. Sundin, T., Dahlstrom, A., Norlen, I., and Svedmeyr, N., The sympathetic innervation and adrenoreceptor function of the human lower urinary tract in the normal state and after parasympathetic denervation, Invest. Urol., 14, 322-328, 1977.
162. Sutherst, J. R., Brown, M. C., and Richmond, D. H., Analysis of the pattern of urine loss in women with incontinence as measured by weighing perineal pads, Br. J. Ural., 58, 273-278, 1986.
163. Sutherst, J. R., Frazer, M. I., Richmond, D. H., and Haylen, B. T., Introduction to Gynaecological Urology, chap. 6, Butterworth-Heinernann, London, 1990, 49-71.
164. Sutherst, J. R. and Brown, M. C., Comparison of single and multichannel cystometry in diagnosing bladder instability, Br. Med. J., 288, 1720-1722, 1984.
165. Swami, S., Abrams, P., Hammonds, J. C., et al., Detrusor myectomy: an alternative to cystoplasty for intractable detrusor instability. Proc. Br. Assoc. Urol. Surgeons Ann. Meeting, Birmingham, U.K., 1994.
166. Swithinbank, L.V., Donovan, J., James, M. C., Yang, Q., and Abrams, P., Female urinary symptoms: age prevalence in a community dwelling population using a validated questionnaire, Neurourol. Urodyn., 16, 432-434, 1997.
167. Tapp, A. J., Versi, E., Cardoza, L., and Studd, J. W., Urethral Instability, Real or Imaginary? Proc. Int. Continence Soc. Meeting, Boston, 1986, 40-42.
168. Tapp, A. J., Cardozo, L. D., Versi, E., and Cooper, D., The treatment of detrusor instability in postmenopausal women with oxybutynin chloride: a double-blind placebo controlled trial, Br. J. Obstets. Gynaecol., 97, 521-526, 1990.
169. Thomas, D. G. and O'Flynn, Spinal cord injury, in Urodynamics; Principles, Practice, and Application, chap. 24, Mundy, A. R., Stephenson, T. P., and Wein, A. J., Eds., Churchill Livingstone, Edinburgh, 1994, 345-358.
170. Thomas, T. M., Plymat, K. R., Blannin, J., and Meade, T. W., Prevalence of urinary incontinence, Br. Med. J., 281, 1243-1245, 1980.
171. Turner-Warwick, R. T., Observations of the function and dysfunction of the sphincter and detrusor mechanisms, Urol. Clin. North Am., 6, 13-30, 1979.
172. Turner-Warwick, R. T. and Handley Ashken, M., The functional results of partial, subtotal, and total cystoplasty with special reference to uretero-caecocystoplasty, selective sphincterotomy and cystocystoplasty, Br. J. Urol., 39, 3-12, 1967.
173. Tyler, D., Stratified squamous epithelium in the vesical trigone and urethra: findings correlated with the menopause cycle and age, Am. J. Anat., 111, 329-335, 1962.
174. Utz, D. C. and Zincke, H., The masquerade of bladder cancer in situ as interstitial cystitis, J. Urol., 111, 160-161, 1974.
175. Van Poppel, H., Stessens, R., Baert, L., Van Damme, B., and Carton, H., Vasoactive intestinal polypeptidergic innervation of human urinary bladder in normal and pathological conditions, Urol. Int., 43, 205-210, 1988.
176. Van Venrooij, G. E., Boon, T. A., and de Hond, J. A., Urodynamics and incontinence. II: the diagnostic value of diuresis cystometry, Int. Urogyn. J., 1, 191-195, 1990.
177. van Koeveringe, G. A., Mostwin, J. L., van Mastrigt, R., and van Koeveringe, B. J., Effect of partial urethral obstruction on force development of the guinea pig bladder, Neururol. Urodyn., 12, 555-571, 1993.
178. van Waalwyk van Doorn, E. S. C., Remmers, A., and Janknegt, R. A., Extramural ambulatory urodynamic monitoring during natural filling and normal daily activities; evaluation of 100 patients, J. Urol., 146, 124-131, 1991.
179. van Waalwyk van Doorn, E. S. C., Remmers, A., and Janknegt, R. A., Conventional and extramural ambulatory urodynamic testing of the lower urinary tract in female volunteers, J. Urol., 147, 1319-1326, 1991.
180. Versi, E., Cardozo, L., Brincat, M., Montgomery, J., and Studd, J., Correlation of urethral physiology and skin collagen in postmenopausal women, Br. J. Obstet. Gynaecol., 95, 147-150, 1988.
181. Versi, E., Griffiths, D. J., and Harvey, M. A., A new external urethral occlusive device for female urinary incontinence, Obstet. Gynecol., 92, 286-291, 1998.
182. Vodusek, D. B., Light, J. K., and Libby, J. M., Detrusor inhibition induced by stimulation of pudendal nerve afferents, Neurourol. Urodyn., 5, 381-389, 1986.
183. Wall, L. L., Norton, P. A., DeLancey, J. O. L., Prolapse and the lower urinary tract, in Practical Urogynecology, chap. 14, Williams & Wilkins, Baltimore, 293-315.
184. Walsh, D. M., TENS Clinical Application and Related Theory, Churchill Livingstone, New York, 1997.
185. Walter, S., Wolf, H., Barlebo, H., and Jensen, K., Urinary incontience in postmenopausal women treated with estrogens, Urol. Int., 33, 135-143, 1978.
186. Walter, S., Oleson, K. P., Nordling, J., and Hald, T., Bladder function in urologically normal middle aged females, Scand. J. Urol. Nephrol., 13, 249-258, 1979.
187. Walters, M. D., Taylor, S., and Schoenfeld, L. S., Psychosexual study of women with detrusor instability, Obstets. Gynecol., 75, 22-26, 1990.
188. Webb, R. J., Styles, R. A., Griffiths, C. J., Ramsden, P. D., and Neeal, D. E., Ambulatory monitoring of bladder pressure in patients with low compliance as a result of neurogenic bladder dysfunction, Br. J. Urol., 64, 150-154, 1989.
189. Webb, R. J., Ramsden, P. D., and Neal, D. E., Ambulatory monitoring and electronic measurement of urinary leakage in the diagnosis of detrusor instability and incontinence, Br. J. Urol., 68, 148-152, 1991.
190. Webb, R. J. and Powell, P. H., Transcutaneous electrical nerve stimulation in patients with idiopathic detrusor instability, Neurourol. Urodyn., 11, 327-328, 1992.
191. Webster, G. D. and Mark, S. D., Neurourology, in Neurosurgery, 2nd ed., Wilkins, R. H. and Rengachary, S. S., Eds., McGraw Hill, New York, 1993.
192. Wein, A. J., Hanno, P. M., and Gillenwatter, J. Y., Interstitial cystitis: an introduction to the problem, in Interstitial Cystitis, chap. 1, Hanno, P. H., Staskin, D. R., Krane, R. J., and Wein, A. J., Eds., Springer Verlag, Berlin, 1990, 3-15.
193. Wheeler, J. S., Walter, J. S., and Cai, W., Electrical stimulation for urinary incontinence, Crit. Rev. Phys. Rehab. Med., 5, 31-56, 1993.
194. Whitfield, H. N. and Mayo, M. E., Prolonged bladder distension in the treatment of the unstable bladder, Br. J. Urol., 47, 635-639, 1975.
195. Whiteside, C. G. and Arnold, E. P., Persistent primary enuresis: a urodynamic assessment, Br. Med. J., 1, 364-367, 1975.
196. Whorwell, P. J., McCallum, M., Creed, F. H., and Roberts, C. T., Noncolonic features of irritable bowel syndrome, Gut, 27, 37-40, 1986a.
197. Whorwell, P. J., Lupton, E. W., Erduran, D., and Wilson, K., Bladder smooth muscle dysfunction in patients with irritable bowel syndrome, Gut, 27, 1014-1017, 1986b.
198. Winkler, H. A. and Sand, P. K., Treatment of detrusor instability with oxybutynin rectal suppositories, Int. Urogynecol. J., 9, 100-102, 1998.
199. Winter, D. L., Receptor characteristics and conduction velocites in bladder afferents, J. Psychiatr. Res., 8, 225-235, 1971.
200. Wiseman, P. A., Malone-Lee, J., and Rai, G. S., Terodiline with bladder retraining for treating detrusor instability in elderly people, Br. Med. J., 302, 994-996, 1991.
201. Zeng, X. P., Moore, K. H., and Burcher, E., Characterization of tachykinin NK-2 receptors in human urinary bladder, J. Urol., 153, 1688-1692, 1996.
202. Zinner, N. R. and Paquin, A. J., Clinical urodynamics. I. Studies of intravesical pressure in normal human female subjects, J. Urol., 90, 719-730, 1963.