Novel cis element for tissue-specific transcription of rat platelet- derived growth factor β-receptor gene

Hypertension

Volumn 33, Issue 1 II, 1999, Pages 298-302

  Takata, Yasunori ^a   Kitami, Yutaka ^a   Fukuoka, Tomikazu ^a   Okura, Takafumi ^a   Hiwada, Kunio ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CCAAT box; cis element; Gene transcription; Muscle, smooth, vascular; NF Y family; Platelet derived growth factors; Promoter

Indexed keywords

DNA; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HYPERTENSION; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; RAT; RECEPTOR GENE; TISSUE SPECIFICITY; VASCULAR SMOOTH MUSCLE;

EID: 0032957699     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.33.1.298     Document Type: Article

References (16)

1. Folkow B, Hallbäck M, Lundgren Y, Sivertsson R, Weiss L. Importance of adaptive changes in vascular design for establishment of primary hypertension, studies in man and in spontaneously hypertensive rats. Circ Res. 1973;32(suppl I):I-2-I-16.
2. Dzau VJ, Gibbons GH, Morishita R, Pratt RE. New perspectives in hypertension research: potentials of vascular biology. Hypertension. 1994;23:1132-1140.
3. Bowen-Pope DF, van Koppen A, Schwatteman G. Is PDGF really important? Testing the hypotheses. Trends Genet. 1991;7:413-418.
4. Robson MC, Phillips LG, Thomason A, Robson LE, Pierce GF. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet. 1992;339:23-25.
5. Robbins SG, Mixon RN, Wilson DJ, Hart CE, Robertson JE, Westra I, Planck SR, Rosenbaum JT. Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal diseases. Invest Ophthalmol Vis Sci. 1990;35:3649-3663.
6. Gesualdo L, Di Paolo S, Milani S, Pinzani M, Grappone C, Ranieri E, Pannarale G, Schena FP. Expression of platelet-derived growth factor receptors in normal and diseased human kidney: an immunohistochemistry and in situ hybridization study. J Clin Invest. 1994;1:50-58.
7. Smits A, Funa K, Vassbotn FS, Beausang-Linder M, af Ekenstam F, Heldin CH Westermark B, Nistér M. Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin. Am J Pathol. 1992;140:639-648.
8. Heldin C-H. Structural and functional studies on platelet-derived growth factor. EMBO J. 1992;11:4251-4259.
9. Lindner V, Reidy MA. Platelet-derived growth factor ligand and receptor expression by large vessel endothelium in vivo. Am J Pathol. 1995;146: 1488-1497.
10. Kitami Y, Fukuoka T, Okura T, Takata Y, Maguchi M, Igase M, Kohara K, Hiwada K. Molecular structure and function of rat platelet-derived growth factor β-receptor gene promoter. J Hypertens. 1998;16:437-445.
11. Kitami Y, Inui H, Uno S, Inagami T. Molecular structure and transcriptional regulation of the gene for the platelet-derived growth factor α receptor in cultured vascular smooth muscle cells. J Clin Invest. 1995; 96:558-567.
12. Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract isolated from mammalian nuclei. Nucl Acids Res. 1983;11:1475-1489.
13. Bucher P. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J Mol Biol. 1990;212:563-578.
14. Maity SN, Sinha S, Ruteshouser EC, de Crombrugghe B. Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor. J Biol Chem. 1992;267:16574-16580.
15. Ballagi AE, Ishizaki A, Nehlin J-O, Funa K. Isolation and characterization of the mouse PDGF β-receptor promoter. Biochem Biophys Res Commun. 1995;210:165-173.
16. Ishisaki A, Murayama T, Ballagi AE, Funa K. Nuclear factor Y controls the basal transcriptional activity of the mouse platelet-derived-growth-factor β-receptor gene. Eur J Biochem. 1997;246:142-146.