Eugenol as an in vivo antioxidant against carbon tetrachloride-induced oxidative stress

Medical Science Research

Volumn 27, Issue 4, 1999, Pages 255-258

  Tamizhselvi, R ^a   Parasakthy, K ^a   Sirajudeen, K N S ^a   Vidhya, N ^a   Niranjali, S ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Carbon tetrachloride; Eugenol; Oxidative stress; Silymarin

Indexed keywords

ANTIOXIDANT; CARBON TETRACHLORIDE; EUGENOL; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; LIPID PEROXIDE; LIVER ENZYME; LIVER PROTECTIVE AGENT; SILYMARIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; LIVER METABOLISM; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALIA; FELIS CATUS;

EID: 0032956984     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Horton A A, Fairhurt S. Lipid peroxidation and mechanism of toxicity. CRC Crir Rev Toxicol 1987; 18:27-32.
2. Floyd RA. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 1990; 4:2587-2597.
3. Halliwell B. Gutteridge JMC. The antioxidants of human extracellular fluids. Arch Biochem Biophys 1990: 280:1-8.
4. Murriel P, Mourella M. Prevention by silymarin of membrane alterations in acute CClj liver damage. J April Joxicol 1990; 10:275-280.
5. Pulla Reddy A.C, Lokesh BR. Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes. Mol Cell Biochem 1992; 111:1 17-124.
6. Parasakthy K, Deepalakshmi PD, Shanthi S, Niranjali S. The hepatoprotective action of eugenol. Med Sei Res 1993; 21:611-612.
7. Fumio F, Sachiko N, Masar K, Kumiko T, Takashi K. Carbon tetraehloride induced alteration of glutathione-S-transferase in rat liver cytosol and plasma. J Clin Biochem Nutr 1989; 6:175-185.
8. Ohkawa H, Ohishi N. Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Annal Chem 1979; 93:351-358.
9. Moron MS, Depierre J, Manncwik B. Levels of glutathione, glutathione reductase and glutathione transferase activities in rat lung and liver. Biochim Biophys Acta 1972; 582:67-78.
10. Fried R, Fried LW. In: Bergmeyer (editor) Methods in Enzymatic Analysis, Vol II. New York: Academic Press; 1966. pp. 644-645.
11. Misra MS, Fridovich I. The role of Superoxide anion in the antioxidation of epinephrine and a simple assay for SOD. J Biol Chem 1972; 247:3170-3175.
12. Beers RF, Sizer IW. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952: 195:133-135.
13. Rotruck JT, Pope AL, Ganther HE. Selenium; Biochemical role as a component of glutathione peroxidase. Science 1973; 179:588-590.
14. Csallany AS, Ayaz KL. Quantitative determination of organic solvent soluble lipofuscin pigment in tissues. Lipids 1976; 11:412-417.
15. Klein RA. The detection of oxidation in liposome preparations. Biochim Biophys Ada 1970; 210:486-488.
16. Dubler RE, Anderson BM. Simultaneous inactivation of the catalytic activities of yeast glutathione reductase by N-alklmaleimides. Biochim Biophys Acta 1981; 659:70-85.
17. Balinsky D, Bernstein RE. The purification and properties of glucose6-phosphate dehydrogenase from human erythrocytes. Biochim Biophys Acta 1963 ; 67:313-315.
18. Habig WH, Pabst MJ. Jakoby WB. Glutathione-S-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249:7130-7139.
19. Lowry OH, Rosebrough NJ, Fair AL, Randall RJ. Protein measurement with the Polin phenol reagent. J Biol Chem 1951; 193:265-275.
20. Thurman RG. Marazzo DP, Jones LS. Kauffman FC. The continuous kinetic determination of p-nitroanisole O-demethylation in hemoglobin-free perfused rat liver. J Pharmacol Exp Ther 1977; 201:498-506.
21. Dianzani MU. The role of free radicals in liver damage. P roc Nutr Soc 1987; 46:43-52.
22. Halliwell B, Gutteridge JMC. In: Free Radicals in Biology and Medicine. Oxford: Clarendon Press; 1989.
23. Lee JA, Briggs RG. Studies on the reconstitution of bovine erythrocyte SOD V. Preparation and properties of derivatives in which both zinc and copper sites contain copper. Biochim Biophys Acta 1975; 400:439-450.
24. Rajakumar DV, Rao MU, Dehydrozingerone and isoeugenol as inhibitors of lipid peroxidation and as free radical scavengers. Biochem Pharmacol 1993; 46:2067-2072.
25. Yokota H, Hashimoto H, Motoya A, Yuasa A. Enhancement of UDPglucuronyl transferase. UDP-glucose dehydrogenase and glutathioneS-transferase activities in rat liver by dietary administration of eugenol. Biochem Pharmacol 1988; 37:799-802.
26. Zheng GQ, Kenney, PM, Lam LK. Sequisterpenes from clove (Eugenia caryophyllata) as potential anticarcinogenic agents. J Nat Prod 1992; 65:999-1003.