Impaired skin vasomotor reflexes in patients with erythromelalgia

Clinical Science

Volumn 96, Issue 5, 1999, Pages 507-512

  Littleford, Roberta C ^a   Khan, Faisel ^a   Belch, Jill J F ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Erythromelalgia; Laser Doppler flowmetry; Skin sympathetic activity; Vasoconstriction

Indexed keywords

CATECHOLAMINE DERIVATIVE;

ADULT; ARTICLE; BLOOD VESSEL TONE; CATECHOLAMINE BLOOD LEVEL; CONTROLLED STUDY; COOLING; DENERVATION; ERYTHEMA; ERYTHROMELALGIA; FEMALE; FINGER; HUMAN; LASER DOPPLER FLOWMETRY; MAJOR CLINICAL STUDY; MALE; NERVE CONDUCTION; PRIORITY JOURNAL; SKIN BLOOD FLOW; SKIN BLOOD VESSEL; SYMPATHETIC INNERVATION; SYMPATHETIC TONE; TOE; VASOCONSTRICTION; VASOMOTOR REFLEX;

ADULT; AGED; CASE-CONTROL STUDIES; COLD; ERYTHROMELALGIA; FINGERS; HUMANS; LASER-DOPPLER FLOWMETRY; MIDDLE AGED; SKIN; STATISTICS, NONPARAMETRIC; TOES; VASOCONSTRICTION;

EID: 0032956913     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS19980341     Document Type: Article

References (32)

1. 1 Mitchell, S. W. (1878) On a rare vaso-motor neurosis of the extremities, and on some maladies with which it may be confounded. Am. J. Med. Sci. 76, 2-36
2. 2 Babb, R. R. and Alarcon-Segovia, D. (1964) Erythermalgia: review of 51 cases. Circulation 29, 36-11
3. 3 Brown, G. E. (1932) Erythromelalgia and other disturbances of the extremities accompanied by vasodilatation and burning. Am. J. Med. Sci. 18, 468-485
4. 4 Fairbairn, J. F., Juergens, J. L. and Spittell, J. A. (1972) Vascular diseases related to environmental temperature. In Peripheral Vascular Diseases (Allen, M. B., Barker, C. D. and Hines, A., eds.), pp. 430-439, WB Saunders, London
5. 5 Vendrell, J., Nubiola, A., Goday, A., Bosch, X., Esmatjes, E., Gomis, R. and Vilardell, E. (1988) Erythromelalgia associated with acute diabetic neuropathy: an unusual condition. Diabetes Res. 7, 149-151
6. 6 Alaron-Segovia, D., Babb, R. R. and Fairnbairn, J. H. (1963) Systemic lupus erythematosus with erythromelalgia. Arch. Int. Med. 112, 688-690
7. 7 Ratz, J. L., Bergfeld, W. F. and Steck, W. D. (1979) Erythromelalgia with vasculitis: a review. J. Am. Acad. Dermatol. 1, 443-450
8. 8 Belch, J. J. F. and Mackay, I. (1992) Erythromelalgia: symptom or syndrome? Vasc. Med. Rev. 3, 31-39
9. 9 Littleford, R., Khan, F. and Belch, J. J. F. (1997) Skin microvascular function in patients with erythromelalgia (EM). Scot. Med. J. 42, 95
10. 10 Michiels, J. J., Abels, J., Steketee, J., Van Vliet, H. H. D. M. and Vuzevski, V. D. (1985) Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. Ann. Intern. Med. 102, 466-471
11. 11 Khan, F., Spence, V. A., Wilson, S. B. and Abbot, N. C. (1991) Quantification of sympathetic vascular responses in skin by laser Doppler flowmetry. Int. J. Microcirc. Clin. Exp. 10, 145-153
12. 12 Grant, R. T. and Bland, E. F. (1931) Observations on arteriovenous anastomoses in human skin and in bird's foot with special reference to the reaction to cold. Heart 15, 385-406
13. 13 Johnson, R. H. and Spalding, J. M. K. (1974) The nervous control of the circulation and its investigation. In Disorders of the Autonomic Nervous System, pp. 33-58, Blackwell, Oxford
14. 14 Sinclair, D. (1973) Motor nerves and reflexes. In The Physiology and Pathophysiology of Skin, vol. 2 (Jarrett, A., ed.), pp. 475-508, Academic Press, London
15. 15 Gilliat, R. W. (1948) Vasoconstriction in the finger after deep inspiration. J. Physiol. (London) 107, 70-88
16. 16 Kvernebo, K. and Seem, E. (1987) Erythromelalgia -pathological and therapeutic aspects. A preliminary report. J. Oslo City Hosp. 37, 9-12
17. 17 Kastrup, J., Nørgaard, T., Parving, H. H. and Lassen, N. A. (1987) Arteriolar hyalinosis does not interfere with the local veno-arteriolar reflex regulation of subcutaneous blood flow in insulin-dependent diabetic patients. Scand. J. Clin. Lab. Invest. 47, 483-489
18. 18 Uno, M. and Parker, F. (1983) Autonomic innervation of the skin in primary erythromclalgia. Arch. Dermatol. 119, 65-71
19. 19 Staub, D. B., Munger, B. L., Uno, H., Dent, C. and Davis, J. S. (1992) Erythromelalgia as a form of neuropathy. Arch. Dermatol. 128, 1654-1655
20. 20 Zoppi, M., Zamponi, A., Pagni, E. and Buonchristiano, U. (1985) A way to understand erythromelalgia. J. Auton. Nerv. Syst. 13, 85-89
21. 21 Drucker, W. R., Hubay, C. A., Holden, W. D. and Bukovnic, J. A. (1959) Pathogenesis of post-traumatic sympathetic dystrophy. Am. J. Surg. 97, 454-465
22. 22 Bonica, J. J. (1953) The Management of Pain, pp. 1064-1065, Lea and Febiger, Philadelphia
23. 23 Telford, E. D. and Simmons, H. T. (1940) Erythromelalgia. Br. Med. J. 2, 782-783
24. 24 Cross, E. G. (1962) The familial occurrence of erythromelalgia and nephritis. Med. Assoc. J. 87, 1-4
25. 25 Smith, L. A. and Allen, E. V. (1938) Erythromalgia (erythromelalgia) of the extremities: a syndrome characterized by redness, heat, and pain. Am. Heart J. 16, 175-188
26. 26 Rósen, L., Östergren, J., Fagrell, B. and Stranden, E. (1988) Skin microvascular circulation in sympathetic dystrophies evaluated by videophotometric capillaroscopy and laser Doppler fluxmetry. Eur. J. Clin. Invest. 18, 305-308
27. 27 Low, P. A., Newman, C., Dyck, P. J., Fealey, R. D. and Tuck, R. R. (1983) Evaluation of skin vasomotor reflexes by using laser Doppler velocimetry. Mayo Clin. Proc. 53, 583-592
28. 28 Goldstein, D. S., Bonner, R. F., Zimlichman, R., Zahn, T. P., Cannon, R. O., Rosing, D. R., Stull, R. and Keiser, H. R. (1986) Indices of sympathetic vascular innervation in sympathectomized patients. J. Auton. Nerv. Syst. 15, 309-318
29. 29 Cameron, N. E., Cotter, M. A. and Low, P. A. (1991) Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am. J. Physiol. 261, E1-E8
30. 30 Vracko, R. (1982) A comparison of the microvascular lesions in diabetic mellitus with those of normal ageing. J. Am. Geriat. Soc. 30, 201-205
31. 31 Drenth, J. P., Vuzevski, V., Van Joost, T., Casteels, Van Daele, M., Vermylen, J. and Michiels, J. J. (1996) Cutaneous pathology in primary erythermalgia. Am. J. Dermatol. 18, 30-34
32. 32 Wilson, S. B., Jennings, P. E. and Belch, J. J. F. (1992) Detection of microvascular impairment in type 1 diabetics by laser Doppler flowmetry. Clin. Physiol. 12, 197-210