Isolation and characterization of biologically active lectin from Korean mistletoe, Viscum album var. Coloratum

Cellular and Molecular Life Sciences

Volumn 55, Issue 4, 1999, Pages 679-682

  Lee, H S ^a   Kim, Y S ^b   Kim, S B ^a   Choi, B E ^a   Woo, B H ^b   Lee, K C ^b  

^a Wonkwang University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Concanavalin A chromatography; Korean mistletoe; MALDI TOF; Mistletoe lectin II (ML II)

Indexed keywords

BASIC PROTEIN; GALACTOSE; N ACETYLGALACTOSAMINE; PROTEIN SUBUNIT; VISCUM ALBUM LECTIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; COLUMN CHROMATOGRAPHY; CYTOTOXICITY; ISOELECTRIC FOCUSING; ISOELECTRIC POINT; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN;

HUMANS; KOREA; LECTINS; MISTLETOE; PLANT LECTINS; PLANT PREPARATIONS; PLANT PROTEINS; PLANTS, MEDICINAL; TOXINS, BIOLOGICAL; TUMOR CELLS, CULTURED;

EID: 0032956658     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180050324     Document Type: Article

References (23)

1. Gabius H. J., Gabius S., Joshi S. S., Koch B., Schroeder M., Manzke W. M. et al. (1994) From ill-defined extracts to the immunomodulatory lectin: will there be a reason for oncological application of mistltoe. Planta Medica 60: 2-7
2. Hajto T. (1986) Immunomodulatory effects of Iscador: a Viscum album preparation. Oncology 43 (Suppl. 1): 51
3. Salzer G. (1986) Pleura Carcinosis, Cytomorphological findings with the mistletoe preparation Iscador and other pharmaceuticals. Oncology 43 (Suppl. 1): 66
4. Hauser S. P. (1993) Unproven methods in cancer treatment. Curr. Opin. Oncol. 5: 646-654
5. Kuttan G., Vasudevan D. M. and Kuttan R. (1988) Isolation and identification of a tumor reducing component from mistletoe extract (Iscador). Cancer Letters 41: 307-314
6. Konopa J., Woynarowski J. M. and Lewandowska-Gumieniak M. (1980) Isolation of viscotoxins. Cytotoxic basic polypeptides from Viscum album L. Hoppe-Seyler's Z. Physiol. Chem. 361: 1525-1533
7. Woynarowski J. M. and Konopa J. (1980) Interaction between DNA and viscotoxins. Cytotoxic basic polypeptides from Viscum album L. Hoppe-Seyler's Z. Physiol. Chem. 361: 1535-1545
8. Jung M. L., Baudino S., Ribereau-Gayon G. and Beck J. P. (1990) Characterization of cytotoxic proteins from mistletoe (Viscum album L.). Cancer Letters 51: 103-108
9. Bussing A. (1996) Induction of apoptosis by the mistletoe lectins: a review on the mechanisms of cytotoxicity mediated by Viscum album L. Apoptosis 1: 25-32
10. Ribereau-Gayon G., Jung M. L., Di Scala D. and Beck J. P. (1986) Comparison of the effects of fermented and unfermented mistletoe preparations on cultured tumor cells. Oncology 43 (Suppl. 1): 35-41
11. Ziska P., Franz H. and Kindt A. (1978) The lectin from Viscum album L. purification by biospecific affinity chromatography. Experientia 34: 123-124
12. Frantz H., Ziska P. and Kindt A. (1981) Isolation and properties of three lectins from mistletoe (Viscum album L.). Biochem. J. 195: 481-484
13. Luther P., Theise H., Chatterjee B., Karduck D. and Uhlenbruck G. (1980) The lectin from Viscum album L. - Isolation, characterization, properties and structure. Int. J. Biochem. 11: 429-435
14. Olsnes S., Stirpe F., Sandvig K. and Phil A. (1982) Isolation and characterization of Viscumin, a toxic lectin from Viscum album L. (Mistletoe). J. Biol. Chem. 257: 13263-13270
15. Vester F., Bohne L. and El Fouly M. (1968) Data on the substances contained in Viscum album, IV, Biological activity of individual protein fractions. Hoppe-Seyler's Z. Physiol. Chem. 349: 495-511
16. Jordan E. and Wagner H. (1986) Structure and properties of polysaccharides from Viscum album (L.). Oncology 43 (Suppl. 1): 8-15
17. Khwaja T. A., Dias C. B. and Pentecost S. (1986) Recent studies on the anticancer activities of Mistletoe (Viscum album) and its alkaloids. Oncology 43(Suppl. 1): 42-50
18. Wagner H., Jordan E. and Feil B. (1986) Studies on the standardization of mistletoe preparation. Oncology 43(Suppl. 1): 16-22
19. Jaggy C., Msielski H., Urech K. and Schaller G. (1995) Quantitative determination of lectins in mistletoe preparations. Arzneim.-Forsch., Drug Res. 45: 905-909
20. Khwaja T. A., Varven J. C., Pentecost S. and Pande H. (1980) Isolation of biologically active alkaloids from Korean mistletoe Viscum album, coloratum. Experientia 36: 599-600
21. Yoon T. J., Yoo Y. C., Choi O. B., Do M. S., Kang T. B., Lee S. W. et al. (1995) Inhibitory effect of Korean mistletoe (Viscum album coloratum) extract on tumor angiogenesis and metastasis of haematogenous and non-haematogenous tumor cells in mice. Cancer Lett. 97: 83-91
22. Ford C. H. J., Richadson V. J. and Tsaltas G. (1989) Comparison of tetrazolium colorimetric and [3H]-uridine assays for in vitro chemosensitivity testing. Cancer Chemo. Pharmacol. 24: 295-301
23. Dietrich J. B., Ribereau-Gayon G., Jung M. L., Franz H., Beck J. P. and Anton R. (1992) Identity of the N-terminal sequences of three A chains of mistletoe (Viscum album L.) lectins: homology with ricin-like plant toxins and single chain ribosome-inhibiting proteins. Anticancer Drugs 3: 507-511