Endogenous neurotensin exerts a tonic stimulatory action on adrenocortical secretion in the rabbit

Medical Science Research

Volumn 27, Issue 1, 1999, Pages 3-5

  Miskowiak, Bogdan ^a   Rebuffat, Piera ^a   Nussdorfer, Gastone G ^a   Malendowicz, Ludwik K ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Adrenocorticotropic hormone; Neurotensin; Pituitary adrenocortical axis; Steroid secretion

Indexed keywords

ALDOSTERONE; CORTICOSTERONE; CORTICOTROPIN; NEUROTENSIN; NEUROTENSIN RECEPTOR ANTAGONIST;

ADRENAL CORTEX FUNCTION; ALDOSTERONE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; CORTICOSTERONE RELEASE; CORTICOTROPIN BLOOD LEVEL; HYPOPHYSIS ADRENAL SYSTEM; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; RABBIT;

EID: 0032955493     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Vincent JP. Neurotensin receptors: binding properties, transduction pathways, and structure. Cell Mol Neurobiol 1995; 15:501-512.
2. Malendowicz LK. Involvement of neuropeptides in the regulation of growth, structure and function of the adrenal cortex. Histal Histopathol 1993; 8: 173-186.
3. Nussdorfer GG. Paracrine control of adrenal cortical function by medullary chromaffin cells. Pharmacol Rev 1996; 48:495-530.
4. Rostene WH, Alexander MJ. Neurotensin and neuroendocrine regulation. Front Neuwendocrinol 1997; 18: 115-173.
5. Nussdorfer GG, Malendowicz LK. Meneghelli V, Mazzocchi G. Neurotensin enhances plasma adrenocorticotropin concentration by stimulating corticotropin-releasing hormone secretion. Life Sei 1992; 50: 639-64?.
6. Malendowic? LK, Nussdorfer GG. Modulatory action of neurotensin on the pituitary-adrenocortical function in rats: evidence for an acute dose-dependent Diphasic effect. Life Sei 1994; 55:201-205.
7. Rowe W. Viau V. Meaney MJ, Quirion R. Stimulation of CRHmediated ACTH secretion by central administration of neurotensin: evidence for the participation of the paraventricular nucleus. J Neumendocriiwl 1995: 7:109-1 17.
8. Maz.zocchi G. Malendowicz LK. Andreis PG. Nussdorfer GG. Neurotensin inhibits the stimulatory effect of angiotensin-11 and potassium on aldosterone secretion by rat zona glomerulosa cells. Exp Clin Emlocrinol 1991: 97:34-38.
9. Malendowicz. LK, Lesniewska B, Miskowiak B, Nussdorfer GG, Nowak M. Effects of neurotensin on the pituitary-adrenocortical axis of intact and dexamethasone-suppressed rats. Exp Pathol 1991: 43:205-21 1.
10. Malendowicz LK, Nussdorfer GG. Hinson JP. Vinson GP. Evidence that endogenous neurotensin exerts a tonic inhibitory influence on adrenal zona glomerulosa growth and secretory activity in the rat. Met/ Sei Res 1996; 24:189-190.
11. Quirion R, Rioux F, Regoli D, St. Pierre S. Selective blockade of neurotensin-induced coronary vessel constriction in perfused rat hearts by a neurotensin analogue. Ear J Pharmacol 1980; 61:309-312.
12. Andreis PC, Neri G, Maz.z.occhi G, Musajo FG. Nussdorfer GG. Direct secretagogue effect of corticotropin-releasing factor on the rat adrenal cortex: the involvement of zona medullaris. Endocrinology 1992: 131: 69-72,
13. Neri G. Malendowicz LK, Andreis PG. Nussdorfer GG. Thyrotrophinreleasing hormone inhibits glueocorticoid secretion of rat adrenal cortex: in vivo and in vitro studies. Endocrinology 1993: 133:511-514.
14. Malendowicz LK, Nussdorfer GG. Markowska A. Nowak KW, Torlinski L. Effects of neuromedin-N on the pituitary-adrenocortical axis of dexamethasone-suppressed rats. Neuropeptides 1993: 24:1-4.
15. Mazzocchi G. Malendowicz LK, Rebuffat P, Gottardo G, Nussdorfer GG. Neurotensin stimulates CRH and ACTH release by rat adrenal medulla in vitro. Neuropeptides 1997: 31: 8-1 1.
16. Goedert M. Mantyh PW, Hunt SP, Emson PC. Localization of specific neurotensin binding sites in the rat adrenal gland. Brain Res 1984; 299: 389-392.