MMP-2 release and activation in ovarian carcinoma: The role of fibroblasts

British Journal of Cancer

Volumn 80, Issue 3-4, 1999, Pages 315-321

  Boyd, R S ^a   Balkwill, F R ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Collagen; Fibroblasts; MMP 2; Ovarian carcinoma; TIMP 2

Indexed keywords

COLLAGEN TYPE 1; GELATINASE A; INTEGRIN; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ARTICLE; CARCINOMA CELL; CELL CULTURE; CELL INTERACTION; CELL MIGRATION; CELL SURFACE; CULTURE MEDIUM; FIBROBLAST; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL;

ANIMALS; CELL COMMUNICATION; CELL MEMBRANE; COCULTURE TECHNIQUES; COLLAGEN; CULTURE MEDIA; ENZYME ACTIVATION; ENZYME PRECURSORS; FEMALE; FIBROBLASTS; GELATINASES; HUMANS; INTEGRINS; MATRIX METALLOPROTEINASE 2; METALLOENDOPEPTIDASES; OVARIAN NEOPLASMS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TUMOR CELLS, CULTURED;

EID: 0032955336     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690357     Document Type: Article

References (42)

1. Afzal S, Lalani E-L, Foulkes WD, Boyce B, Tickle S, Cardillo M-R, Baker T. Pignatelli M and Stamp GWH (1996) Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumour cell lines. Lab Invest 2: 406-421
2. Atkinson SJ, Crabbe T, Cowell S, Ward R, Butler MJ, Sato H, Seiki M, Reynolds JJ and Mutphy G (1995) Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J Biol Chem 270: 30479-30485
3. Autio-Harmainen H, Karttunen T, Hurskainen T, Hoyhtya M and Kauppila A (1993) Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumours. Lab Invest 69: 312-321
4. Azzam HS and Thompson EW (1992) Collagen-induced activation of the M, 72 type IV collagenase in normal and malignant human fibroblastoid cells. Cancer Res 52: 4540-4544
5. Baramova EN, Bajou K, Remacle A, Lihoir C, Krell HW, Weidle UH, Noel A and Foidart JM (1997) Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of proMMP-2 activation. FEBS Letts 405: 157-162
6. Birkedal-Hansen H (1995) Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7: 728-735
7. Bordier C (1981) Phase separation of integral membrane proteins in Triton X-114 solution. J Biol Chem 256: 1604-1607
8. Campo E, Merino MJ, Tavassoli FA, Charonis AS and Stetler-Stevenson WG (1992) Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumours of the ovary. Am J Surg Pathol 16: 500-507
9. Fishman DA, Bafetti LM and Stack MS (1997) Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells. Inv Metastasis 16: 150-159
10. Garzetti G, Ciavattini A, Lucarini G, Goteri G, Nictolis MD, Garbisa S, Masiero L, Romanini C and Graziella B (1995) Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystodenocarcinomas: clinical and prognostic implications. Anticancer Res 15: 2799-2804
11. Gilles C, Polette M, Seiki M, Birembaut P and Thompson EW (1997) Implication of collagen type-1 induced membrane-type 1-matrox metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest 76: 651-660
12. Greene J, Wang M, Liu YI, Raymond LA, Rosen C and Shi YI (1996) Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J Biol Chem 271: 30375-30378
13. Ito A, Nakajima S, Sasaguri Y, Nagase H and Mori Y (1995) Co-culture of human breast adenocarcinoma MCF-7 cells and human dermal fibroblasts enhances the production of matrix metalloproteinases 1, 2 and 3 in fibroblasts. Br J Cancer 71: 1039-1045
14. Kataoka H, Decastro R, Zucker S and Biswas C (1993) Tumour cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromeolysin, and 72 kDa gelatinase. Cancer Res 53: 3154-3158
15. Kikkawa F, Tamakoshi K, Nawa K, Shibata K, Yamagata S, Yamagata T and Suganuma N (1997) Positive correlation between inhibitors of matrix metalloproteinase 1 and matrix metalloproteinases in malignant ovarian tumour tissues. Cancer Letts 120: 109-115
16. Kolenbrock H, Hecker-Kia A, Orgel D, Ulbrich N and Will H (1997) Activation of progelatinase A and progelatinase A/TIMP-2 complex by membrane type 2-matrix metalloproteinase. J Biol Chem 378: 71-76
17. Kubota S, Ito H and Seyama Y (1997) Anti-alpha3 integrin antibody induces the activated form of matrix metalloprotease-2 (MMP-2) with concomitant stimulation of invasion through matrigel by human rhabdomyosarcoma cells. Int J Cancer 70: 106-111
18. Kuwashima Y, Uehara T, Kurosumi M, Kishi K, Shironizu K, Matsuzawa M and Takayama S (1995) Basement membrane status I undifferentiated carcinomas of the ovary: immunohistochemical distribution of type IV collagen and laminin. Eur J Gynaecol Oncol 16: 181-186
19. Leber TM and Balkwill FR (1997) Zymography: a single-step staining method for quantitation of proteolytic activity on substrate gels. Anal Biochem 249: 24-28
20. Lee AY, Akers KT, Collier M, Li L, Eisen AZ and Louise-Seltzer J (1997) Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts. Proc Natl Acad Sci USA 94: 4424-4429
21. Lewalle JM, Munaut C, Pichot B, Cataldo D, Baramova E and Foidart JM (1995) Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells. J Cell Physiol 165: 475-483
22. Liabakk N-B, Talbot I, Smith RA, Wilkinson K and Balkwil FB (1996) Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res 56: 190-196
23. Liotta LA, Steeg PS and Steteler-Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cancer Res 64: 327-336
24. Lohi J, Lehti K, Westermarck J, Kahari V-M and Keski-Oja J (1996) Regulation of membrane-type matrix metalloprotease-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur J Biochem 239: 239-247
25. Moser TL, Young TN, Rodriguez GC, Pizzo SV, Bast RC and Stack MS (1994) Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma. Int J Cancer 56: 552-559
26. Naylor MS, Stamp GW, Davies BD and Balkwill FR (1994) Expression and activity of MMPs and their regulators in ovarian cancer. Int J Cancer 58: 50-56
27. Niedbala MJ, Crickard K and Bernacki RJ (1987) In vitro degradation of extracellular matrix by human ovarian carcinoma cells. Clin Exp Metastasis 5: 181-197
28. Noel A, Munaut C, Boulvain A, Calberg-Bacq CM, Nusgens B, Lapiere CM and Foidart JM (1992) Modulation of collagen and fibronectin synthesis in fibroblasts by normal and malignant cells. J Cell Biochem 48: 150-161
29. Noel A, Polette M, Lewalle J-M, Munaut C, Emonard HP, Birembaut P and Foidart J-M (1994) Co-ordinate enhancement of gelatinase A mRNA and activity levels in human fibroblasts in response to breast-adenocarcinoma cells. Int J Cancer 56: 331-336
30. Obtani H, Motohashi H, Sato H, Seiki M and Nagura H (1996) Dual overexpression of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy. Int J Cancer 68: 565-570
31. Okada A, Bellocq J-P, Rouyer N, Chenard M-P, Rio M-C, Chambon P and Basset P (1995) Membrane-type metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl Acad Sci USA 92: 2730-2734
32. Ray JM and Stetler-Stevenson WG (1995) Gelatinase A activity directly modulates melanoma cell adhesion and spreading. EMBO J 14: 908-917
33. Sato H, Takino T, Okada O, Kada O, Cao J, Shinagawa A, Yamamoto E and Seiki M (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370: 61-65
34. Seltzer JL, Lee A-Y, Akers KT, Sudbeck B, Eileen A, Southon EA, Wayner EA and Eisen AZ (1994) Activation of 72-kDa collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. Exp Cell Res 213: 365-374
35. Shofuda K, Yasumitsu H, Nishihashi A, Miki K and Miyazaki K (1997) Expression of three matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain. J Biol Chem 272: 9749-9754
36. Stetler-Stevenson WG, Krutzsch HC, Wacher MP, Maragulłiies IMK and Liotta IA (1989a) The activation of human type IV collagenase proenzyme: sequence identificalion of the major conversion product following organo-mecurial activation. J Biol Chem 264: 1353-1360
37. Stetler-Stevenson WG, Krutzsch HC and Liotta IA (1989b) Tissue inhibitors of metalloproteinase (TIMP-2): a new member of the metalloproteinase inhibitor family. J Biol Chem 264: 17374-17378
38. Strongin AY, Cillier I, Bannikov G, Marmer BL, Grant GA and Goldberg GI (1995) Mechanism of cell surface activation of 72 kDa type IV collagenase J Biol Chem 270: 5331-5338
39. Tamakoshi K, Kikkawa F, Nawa A, Ishikawa H, Mizuno K, Tamakoshi A, Yamagata S, Suganuma N and Tomoda Y (1995) Characterisation of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form. Cancer 76: 2565-2571
40. Westerlund A, Hujanen E, Puistola U and Turpeenniemi-Hujanen T (1997) Fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2). Gynecol Oncol 67: 76-82
41. Ueno H, Nakamura H, Inoue M, Imai M, Imai K, Noguchi M, Sato H, Seiki M and Okada Y (1997) Expression and tissue localization of membrane-types 1, 2 and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 57: 2055-2060
42. Zhu G-G, Risteli L, Risteli J, Kauppila M and Stenback F (1994) Immunohistochemical study of type I collagen and type I pH-collagen in benign and malignant neoplasms. Cancer 75: 1010-1017