Acute haemodynamic and proteinuric effects of prednisolone in patients with a nephrotic syndrome

Nephrology Dialysis Transplantation

Volumn 14, Issue 1, 1999, Pages 91-97

  Reichert, Louis J M ^a,b   Koene, Robert A P ^a   Wetzels, Jack F M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Maaslandziekenhuis ^*  (Netherlands)

Author keywords

Angiotensin converting enzyme; Nephrotic syndrome; Prednisolone; Prostaglandins; Proteinuria; Urinary albumin excretion; Urinary transferrin excretion

Indexed keywords

ALBUMIN; BETA 2 MICROGLOBULIN; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOGLOBULIN G; INDOMETACIN; LISINOPRIL; PREDNISOLONE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN; TRANSFERRIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; FEMALE; GLOMERULUS FILTRATION RATE; HEMODYNAMICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY BLOOD FLOW; KIDNEY PLASMA FLOW; MALE; MOLECULAR WEIGHT; NEPHROTIC SYNDROME; PRIORITY JOURNAL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; AGED; ALBUMINURIA; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BETA 2-MICROGLOBULIN; BLOOD PRESSURE; CYCLOOXYGENASE INHIBITORS; FEMALE; GLOMERULAR FILTRATION RATE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; IMMUNOGLOBULIN G; INDOMETHACIN; INJECTIONS, INTRAVENOUS; LISINOPRIL; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; PLACEBOS; PREDNISOLONE; PROTEINURIA; RENAL CIRCULATION; TRANSFERRIN;

EID: 0032952178     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/14.1.91     Document Type: Article

References (21)

1. Collaborative Study of the Adult Idiopathic Nephrotic Syndrome A controlled study of short-term prednisone treatment in adults with membranous nephropathy. N Engl J Med 1979; 301: 1301-1306
2. Wetzels JFM, Gerlag PGG, Sluiter HE, Hoitsma AJ, Koene RAP. Prednisone-induced fluctuations of proteinuria in patients with a nephrotic syndrome. Nephron 1986; 44: 344-350
3. Kumagai H, Hishida A, Nagase M, Honda N. Mechanisms of steroid enhanced proteinuria in nephrotic patients. Nippon Jinzo Gakkai Shi 1987; 29: 277-281
4. Wetzels JFM, Hoitsma AJ, Koene RAP. Decreases of proteinuria during alternate-day prednisone therapy in nephrotic syndrome. Nephrol Dial Transplant 1990; 5: 914-919
5. Heymann W, Grupe WE. Increase in proteinuria due to steroid medication in chronic renal disease. J Pediatr 1969; 74: 356-363
6. Zager RA. Effects of glucocorticoid administration on urinary albumin excretion by the normal kidney. Renal Physiol 1981; 4: 37-45
7. Wetzels JFM, Sluiter HE, Hoitsma AJ, van Munster PJJ, Koene RAP. Prednisolone can increase glomerular permeability to proteins in nephrotic syndrome. Kidney Int 1988; 33: 1169-1174
8. Koopman MG, Krediet RT, Koomen GC, Strackee J, Arisz L. Circadian rhythm of proteinuria: consequences of the use of urinary protein : creatmine ratios. Nephrol Dial Transplant 1989; 4: 9-14
9. Elving LD, Bakkeren JAJM, Jansen MJH, de Kat Angelino CM, de Nobel E, van Munster PJJ. Screening for microalbuminuria in patients with diabetes mellitus: frozen storage of urine samples decreases their albumin content. Clin Chem 1989; 35: 308-310
10. Reichert LJM, Koene RAP, Wetzels JFM. Urinary IgG excretion as a prognostic factor in idiopathic membranous nephropathy. Clin Nephrol 1997; 48: 79-84
11. Thielemans N, Lauwerys R, Bernard A. Competition between albumin and low-molecular-weight proteins for renal tubular uptake in experimental nephropathies. Nephron 1994; 66: 453-458
12. Webel ML, Donadio JV, Woods JE, Maher FT. Effects of a large dose of methylprednisolone on renal function. J Lab Clin Med 1972; 80: 765-771
13. Mills JN, Thomas S. The acute effects of cortisone and cortisol upon renal function in man. J Endocrinol 1958; 17: 41-53
14. Jick H, Snijder JG, Finkelstein EM, Cohen JL, Moore EW, Morrison RS. On the renal site and mode of action of glucocorticoid in cirrhosis. J Clin Invest 1963; 42: 1561-1568
15. Dimitrov Y, Moulin B, Chantrel F, Schmitt F, Lacour B, Hannedouche T. Effects of acute administration of methylprednisolone (MPS) on renal haemodynamics in proteinuric patients. J Am Soc Nephrol 1996; 7: 1579 (Abstract)
16. Raisz LG, McNeely WF, Saxon L, Rosenbaum JD. The effects of cortisone and hydrocortisone on water diuresis and renal function in man. J Clin Intest 1957; 36: 767-779
17. Popotzer MM, Pinggera WF, Robinette J, Holmes JH, Halgrimson CG, Starzl TE. Acute renal response to large doses of intravenous prednisolone in kidney homograft recipients and in normal subjects. J Lab Clin Med 1974; 78: 39-52
18. Krakoff LR, Eligovich F. Cushing's syndrome and exogenous glucocorticoid hypertension. Clin Endocrinol Metab 1981; 10: 479-488
19. Pessina AC, Pearl WS. Renin-induced proteinuria and the effects of adrenalectomy. I. Hemodynamic changes in relation to function. Proc R Soc (London) 1972; 180B: 43-60
20. Bauman JW. Corticoid effects on angiotensin-and norepinephrine-induced proteinuria in rats. Am J Physiol 1979; 237: F133-137
21. Nasjletti A, Erman A, Cagen LM, Baer PG. Plasma concentrations, renal excretion and tissue release of prostaglandins in the rat with dexamethasone-induced hypertension. Endocrinology 1984; 114: 1033-1040