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Volumn 125, Issue 3, 1999, Pages 257-264

Adjuvant immunotherapy using fibroblasts genetically engineered to secrete interleukin 12 prevents recurrence after surgical resection of established tumors in a murine adenocarcinoma model

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; TUMOR VACCINE;

EID: 0032952107     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(99)70235-7     Document Type: Article
Times cited : (12)

References (34)
  • 2
    • 0025875022 scopus 로고
    • Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
    • Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, et al. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol 1991;146:3074-81.
    • (1991) J Immunol , vol.146 , pp. 3074-3081
    • Wolf, S.F.1    Temple, P.A.2    Kobayashi, M.3    Young, D.4    Dicig, M.5    Lowe, L.6
  • 3
    • 0026592604 scopus 로고
    • Mechanisms of IFN-γ induction by natural killer cell stimulatory factor (NKSF/Il-12): Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2
    • Chan SH, Kobayashi M, Santoli D, Perussian B, Trinchieri G. Mechanisms of IFN-γ induction by natural killer cell stimulatory factor (NKSF/Il-12): role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2. J Immunol 1992;148:92-8.
    • (1992) J Immunol , vol.148 , pp. 92-98
    • Chan, S.H.1    Kobayashi, M.2    Santoli, D.3    Perussian, B.4    Trinchieri, G.5
  • 5
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995;13:251-76.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 6
    • 0025873502 scopus 로고
    • Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)
    • Gately MK, Desai BB, Wolitzky AG, Quinn PM, Dwyer CM, Podlaski FJ, et al. Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J Immunol 1991;147:874-82.
    • (1991) J Immunol , vol.147 , pp. 874-882
    • Gately, M.K.1    Desai, B.B.2    Wolitzky, A.G.3    Quinn, P.M.4    Dwyer, C.M.5    Podlaski, F.J.6
  • 8
    • 0027963161 scopus 로고
    • Recombinant IL-12 administration induces tumor regression in ssociation with IFN-γ production
    • Nastala CL, Edington HD, Mckinney TG, Tahara H, Nalesnik MA, Brunda MJ, et al. Recombinant IL-12 administration induces tumor regression in ssociation with IFN-γ production. J Immunol 1994;153:1697-706.
    • (1994) J Immunol , vol.153 , pp. 1697-1706
    • Nastala, C.L.1    Edington, H.D.2    Mckinney, T.G.3    Tahara, H.4    Nalesnik, M.A.5    Brunda, M.J.6
  • 10
    • 0029039610 scopus 로고
    • Systemic administration of rIL-12 induces complete tumor regression and protective immunity: Response is correlated with a striking reversal of suppressed IFNγ production by anti-tumor T cells
    • Zou J-P, Yamamoto N, Fujii T, Takenaka H, Kobayashi M, Herrmann SH, et al. Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFNγ production by anti-tumor T cells. Int Immunol 1995;7:1135-45.
    • (1995) Int Immunol , vol.7 , pp. 1135-1145
    • Zou, J.-P.1    Yamamoto, N.2    Fujii, T.3    Takenaka, H.4    Kobayashi, M.5    Herrmann, S.H.6
  • 11
    • 0029148905 scopus 로고
    • Cancer immunotherapy of established tumors with IL-12: Effective delivery by genetically engineered fibroblasts
    • Zitvogel L, Tahara H, Robbins P, Storkus W, Clarke M, Lotze MT. Cancer immunotherapy of established tumors with IL-12: effective delivery by genetically engineered fibroblasts. J Immunol 1995;155:1393-403.
    • (1995) J Immunol , vol.155 , pp. 1393-1403
    • Zitvogel, L.1    Tahara, H.2    Robbins, P.3    Storkus, W.4    Clarke, M.5    Lotze, M.T.6
  • 12
    • 0028096083 scopus 로고
    • Administration of recombinant IL-12 to normal mouse enhances cytolytic lymphocyte activity and induces production of IFNγ in vivo
    • Gately MK, Warrier R, Honasoge S, Carvajal D, Faherty D, Connaughton S, et al. Administration of recombinant IL-12 to normal mouse enhances cytolytic lymphocyte activity and induces production of IFNγ in vivo. Int Immunol 1994;6:157-67.
    • (1994) Int Immunol , vol.6 , pp. 157-167
    • Gately, M.K.1    Warrier, R.2    Honasoge, S.3    Carvajal, D.4    Faherty, D.5    Connaughton, S.6
  • 13
    • 0016696542 scopus 로고
    • Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assay, with a note on carcinogen structure
    • Corbett TH, Griswold D, Roberts B, Peckham J, Schabel F Jr. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assay, with a note on carcinogen structure. Cancer Res 1975;35:2434-7.
    • (1975) Cancer Res , vol.35 , pp. 2434-2437
    • Corbett, T.H.1    Griswold, D.2    Roberts, B.3    Peckham, J.4    Schabel Jr., F.5
  • 14
    • 0027953555 scopus 로고
    • Fibroblast genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo
    • Tahara H, Herbert J-Zeh III, Lotze MT. Fibroblast genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res 1994;54:182-9.
    • (1994) Cancer Res , vol.54 , pp. 182-189
    • Tahara, H.1    J-Zeh III, H.2    Lotze, M.T.3
  • 15
    • 0028928622 scopus 로고
    • CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with IL-12 genes
    • Martinotti A, Stoppacciaro A, Vagliani M, Melani C, Spreafico F, Wysocka M, et al. CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with IL-12 genes. Eur J Immunol 1995;25:137-46.
    • (1995) Eur J Immunol , vol.25 , pp. 137-146
    • Martinotti, A.1    Stoppacciaro, A.2    Vagliani, M.3    Melani, C.4    Spreafico, F.5    Wysocka, M.6
  • 16
    • 0029898839 scopus 로고    scopus 로고
    • Amount of interleukin 12 available at the tumor site is critical for tumor regression
    • Colombo MP, Vagliani M, Spreafico F, Parenza M, Chiodoni C, Melani C, et al. Amount of interleukin 12 available at the tumor site is critical for tumor regression. Cancer Res 1996;56:2531-4.
    • (1996) Cancer Res , vol.56 , pp. 2531-2534
    • Colombo, M.P.1    Vagliani, M.2    Spreafico, F.3    Parenza, M.4    Chiodoni, C.5    Melani, C.6
  • 17
    • 0028625325 scopus 로고
    • Construction and characterization of retroviral vectors expressing biologically active human IL-12
    • Zitvogel L, Tahara H, Cai Q, Robbins P, Storkus W, Muller G, et al. Construction and characterization of retroviral vectors expressing biologically active human IL-12. Hum Gene Ther 1994;5:1493-506.
    • (1994) Hum Gene Ther , vol.5 , pp. 1493-1506
    • Zitvogel, L.1    Tahara, H.2    Cai, Q.3    Robbins, P.4    Storkus, W.5    Muller, G.6
  • 18
    • 0014604721 scopus 로고
    • Murine sarcoma and leukemia viruses: Assayusing clonal lines of contact-inhibited mouse cells
    • Jainchill JL, Aaronson S, Todaro G. Murine sarcoma and leukemia viruses: assayusing clonal lines of contact-inhibited mouse cells. J Virol 1969;4:549-53.
    • (1969) J Virol , vol.4 , pp. 549-553
    • Jainchill, J.L.1    Aaronson, S.2    Todaro, G.3
  • 19
    • 0029961016 scopus 로고    scopus 로고
    • Intensified antitumor immunity by a cancer vaccine that produces granulocyte-macrophage colony-stimulating factor plus interleukin 4
    • Wakimoto H, Abe J, Tunoda R, Aoyagi M, Hirakawa K, Hamada H. Intensified antitumor immunity by a cancer vaccine that produces granulocyte-macrophage colony-stimulating factor plus interleukin 4. Cancer Res 1996;56:1828-33.
    • (1996) Cancer Res , vol.56 , pp. 1828-1833
    • Wakimoto, H.1    Abe, J.2    Tunoda, R.3    Aoyagi, M.4    Hirakawa, K.5    Hamada, H.6
  • 20
    • 0342463159 scopus 로고
    • Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges
    • Danos O, Mulligan RC. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc Natl Acad Sci USA 1988;85:6460-4.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6460-6464
    • Danos, O.1    Mulligan, R.C.2
  • 21
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993;90:3539-43.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6
  • 22
    • 0023118403 scopus 로고
    • Integration and expression of retrovirus leads to the expression of a histocompatibility antigen detected by skin graft rejection
    • Colombo MP, Jaenisch R, Wettstein PJ. Integration and expression of retrovirus leads to the expression of a histocompatibility antigen detected by skin graft rejection. Proc Natl Acad Sci USA 1987;84:189-93.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 189-193
    • Colombo, M.P.1    Jaenisch, R.2    Wettstein, P.J.3
  • 23
    • 0026062931 scopus 로고
    • Therapeutic use of a long-term cytotoxic T cell line recognizing a common tumor-associated antigen: The pattern of in vitro reactivity predicts the in vivo effect on different tumors
    • Rodolfo M, Bassi C, Salvi C, Parmiani G. Therapeutic use of a long-term cytotoxic T cell line recognizing a common tumor-associated antigen: the pattern of in vitro reactivity predicts the in vivo effect on different tumors. Cancer Immunol Immunother 1991;34:53-62.
    • (1991) Cancer Immunol Immunother , vol.34 , pp. 53-62
    • Rodolfo, M.1    Bassi, C.2    Salvi, C.3    Parmiani, G.4
  • 24
    • 0024584020 scopus 로고
    • Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
    • Stuehr DJ, Nathan CF. Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med 1989;169:1543-55.
    • (1989) J Exp Med , vol.169 , pp. 1543-1555
    • Stuehr, D.J.1    Nathan, C.F.2
  • 25
    • 0028096083 scopus 로고
    • Administration of recombinant IL-12 to normal mouse enhances cytolytic lymphocyte activity and induces production of IFN-gammma in vivo
    • Gately MK, Warrier R, Honasoge S, Carvajal D, Faherty D, Connaughton S, et al. Administration of recombinant IL-12 to normal mouse enhances cytolytic lymphocyte activity and induces production of IFN-gammma in vivo. Int Immunol 1994;6:157-67.
    • (1994) Int Immunol , vol.6 , pp. 157-167
    • Gately, M.K.1    Warrier, R.2    Honasoge, S.3    Carvajal, D.4    Faherty, D.5    Connaughton, S.6
  • 26
    • 0019929408 scopus 로고
    • Preferential effect of interferon-γ on the synthesis of HLA antigens and their mRNAs in human cells
    • Wallach D, Fellous M, Revel M. Preferential effect of interferon-γ on the synthesis of HLA antigens and their mRNAs in human cells. Nature 1982;299:833-6.
    • (1982) Nature , vol.299 , pp. 833-836
    • Wallach, D.1    Fellous, M.2    Revel, M.3
  • 27
    • 0030070446 scopus 로고    scopus 로고
    • Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12
    • Tannenbaum CS, Wicker N, Armstrong D, Tubbs R, Finke J, Bukowski RM, et al. Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12. J Immunol 1996;156:693-9.
    • (1996) J Immunol , vol.156 , pp. 693-699
    • Tannenbaum, C.S.1    Wicker, N.2    Armstrong, D.3    Tubbs, R.4    Finke, J.5    Bukowski, R.M.6
  • 29
    • 0025000864 scopus 로고
    • Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity
    • Gansbacher B, Zeier K, Daniels B, Cronin K, Bennerji R, Gilboa E. Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J Exp Med 1990;172:1217-24.
    • (1990) J Exp Med , vol.172 , pp. 1217-1224
    • Gansbacher, B.1    Zeier, K.2    Daniels, B.3    Cronin, K.4    Bennerji, R.5    Gilboa, E.6
  • 30
    • 0025119692 scopus 로고
    • Low doses of IL4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory
    • Bosco M, Giovarelli M, Forni M, Modesti A, Scarpa S, Masuelli L, et al. Low doses of IL4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory. J Immunol 1990;145:3136-43.
    • (1990) J Immunol , vol.145 , pp. 3136-3143
    • Bosco, M.1    Giovarelli, M.2    Forni, M.3    Modesti, A.4    Scarpa, S.5    Masuelli, L.6
  • 31
    • 0026772066 scopus 로고
    • Interleukin 6 gene transfection into Lewis lung carcinoma tumor cells suppresses the malignant phenotype and confers immunotherapeutic competence against parental metastatic cells
    • Porgador A, Tzehoval E, Katz A, Vadai E, Revel M, Feldman M, et al. Interleukin 6 gene transfection into Lewis lung carcinoma tumor cells suppresses the malignant phenotype and confers immunotherapeutic competence against parental metastatic cells. Cancer Res 1992;52:3679-86.
    • (1992) Cancer Res , vol.52 , pp. 3679-3686
    • Porgador, A.1    Tzehoval, E.2    Katz, A.3    Vadai, E.4    Revel, M.5    Feldman, M.6
  • 32
    • 0025604195 scopus 로고
    • Retroviral vector-mediated g-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity
    • Gansbacher B, Bennerji R, Daniels B, Zeier K, Cronin K, Gilboa E. Retroviral vector-mediated g-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity. Cancer Res 1990;50:7820-5.
    • (1990) Cancer Res , vol.50 , pp. 7820-7825
    • Gansbacher, B.1    Bennerji, R.2    Daniels, B.3    Zeier, K.4    Cronin, K.5    Gilboa, E.6
  • 33
    • 0026453626 scopus 로고
    • Role of neutrophhils and CD4+ T lymphocytes in the primary and memory response to nonimmunogenic murine mammary adenocarcinoma made immunogenic by IL-2 gene
    • Cavallo F, Giovarelli M, Gulino A, Stoppacciaro A, Modesti A, Forni G. Role of neutrophhils and CD4+ T lymphocytes in the primary and memory response to nonimmunogenic murine mammary adenocarcinoma made immunogenic by IL-2 gene. J Immunol 1992;149:3627-35.
    • (1992) J Immunol , vol.149 , pp. 3627-3635
    • Cavallo, F.1    Giovarelli, M.2    Gulino, A.3    Stoppacciaro, A.4    Modesti, A.5    Forni, G.6
  • 34
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper RI, Pattengal PK, Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989;57:503-12.
    • (1989) Cell , vol.57 , pp. 503-512
    • Tepper, R.I.1    Pattengal, P.K.2    Leder, P.3


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