Characterization of active-site aromatic residues in xylanase a from Streptomyces lividans

Protein Engineering

Volumn 12, Issue 3, 1999, Pages 251-257

  Roberge, Martin ^a,b   Shareck, François ^a   Morosoli, Rolf ^a   Kluepfel, Dieter ^a   Dupont, Claude ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

^b GENENTECH INC   (United States)

Author keywords

Family 10 hydrolase; Glycosyl hydrolase; Site directed mutagenesis; Structure function; Xylanase

Indexed keywords

AROMATIC AMINO ACID; XYLAN ENDO 1,3 BETA XYLOSIDASE;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVE SITE; ENZYME KINETICS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STREPTOMYCES LIVIDANS; STRUCTURE ACTIVITY RELATION;

ACTINOBACTERIA (CLASS); STREPTOMYCES LIVIDANS; UNCULTURED ACTINOMYCETE;

EID: 0032951165     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/12.3.251     Document Type: Article

References (23)

1. Bertrand, J.-L., Morosoli, R., Shareck, F. and Kluepfel, D. (1989) Biotechnol. Bioengng, 33, 791-794.
2. Bray, M.R. and Clarke, A.J. (1995) Biochemistry, 34, 2006-2014.
3. Davies, G.J., Wilson, K.S. and Henrissat, B. (1997) Biochem. J., 321, 557-559.
4. Derewenda, U., Swenson, L., Green, R., Wei, Y.Y., Morosoli, R., Shareck, F., Kluepfel, D. and Derewenda, Z.S. (1994) J. Biol. Chem., 269, 20811-20814.
5. Dominguez, R., Souchon, H., Spinelli, S., Dauter, Z., Wilson, K.S., Chauvaux, S., Beguin, P. and Alzari, P.M. (1995) Nature Struct. Biol., 2, 569-576.
6. Dupont, C., Roberge, M., Shareck, F., Morosoli, R. and Kluepfel, D. (1998) Biochem. J., 330, 41-45.
7. Harris, G.W., Jenkins, J.A., Connerton, I., Cummings, N., Lo Leggio, L., Scott, M., Hazlewood, G.P., Laurie, J.I., Gilbert, H.J. and Pickersgill, R.W. (1994) Structure, 2, 1107-1116.
8. Harris, G.W., Jenkins, J.A., Connerton, I. and Pickersgill, R.W. (1996) Acta Crystallogr., Sect. D, 52, 393-401.
9. Henrissat, B. and Bairoch, A. (1998) Swiss-Prot Protein Sequence Data Bank, Release 35.0, and updates up to March 1998.
10. Keskar, S.S., Srinivasan, M.C. and Deshpande, V.V. (1989) Biochem. J., 261, 49-55.
11. Kunkel, T.A. (1985) Proc. Natl Acad. Sci. USA, 82, 488-492.
12. Lever, M., Walmsley, T.A., Visser, R.S. and Ryde, S.J. (1984) Anal. Biochem., 139, 205-211.
13. Moreau, A., Roberge, M., Manin, C., Shareck, F., Kluepfel, D. and Morosoli, R. (1994) Biochem. J., 302, 291-295.
14. Notenboom, V., Birsan, C., Warren, R.A.J., Withers, S.G. and Rose, D.R. (1998) Biochemistry, 37, 4751-4758.
15. Pace, C.N., Shirley, B.A. and Thomson, J.A. (1989) In Creighton, T.E. (ed.), Protein Structure; a Practical Approach. IRL Press, Oxford, pp. 311-330.
16. Quiocho, F.A. (1986) Annu. Rev. Biochem., 55, 287-315.
17. Roberge, M., Dupont, C., Morosoli, R., Shareck, F. and Kluepfel, D. (1997a) Protein Engng, 10, 399-403.
18. Roberge, M., Shareck, F., Morosoli, R., Kluepfel, D. and Dupont, C. (1997b) Biochemistry, 36, 7769-7775.
19. Roberge, M., Shareck, F., Morosoli, R., Kluepfel, D. and Dupont, C. (1998) Protein Engng, 5, 399-404.
20. Shareck, F., Roy, C., Yaguchi, M., Morosoli, R. and Kluepfel, D. (1991) Gene, 107, 75-82.
21. Sinnott, M.L. (1990) Chem. Rev., 90, 1171-1202.
22. Wilkinson, A.J., Fersht, A.R., Blow, D.M. and Winther, G. (1983) Biochemistry, 22, 3581-3586.
23. White, A., Tull, D., Johns, K., Withers, S.G. and Rose, D.R. (1996) Nature Struct. Biol., 3, 149-154.