Effects of free radical scavengers on histamine release from human basophils stimulated by immunological and non-immunological secretagogues

Inflammation Research

Volumn 48, Issue SUPPL. 1, 1999, Pages

  Gibbs, B F ^a   Wolff, H H ^a   Grabbe, J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; AMBROXOL; CALCIMYCIN; CALCIUM IONOPHORE; CYTOKINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FREE RADICAL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 3; SCAVENGER;

BASOPHIL; CONFERENCE PAPER; HISTAMINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION;

ACETYLCYSTEINE; AMBROXOL; BASOPHILS; CALCIMYCIN; FREE RADICAL SCAVENGERS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTAMINE RELEASE; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-3; IONOPHORES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; VITAMIN E;

EID: 0032950832     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (7)

1. Pfeifer S, Zissel G, Kienast K, Muller-Quernhaim J. Reduction of cytokine release of blood and bronchoalveolar mononuclear cells by ambroxol. Eur J Med Res 1997; 2: 129-32.
2. Kharazmi A, Nielsen H, Schiotz, PO. N-acetylcysteine inhibits human neutrophil and monocyte chemotaxis and oxidative metabolism. Int J Immunopharmacol 1998; 10: 39-46.
3. Kristensen KS, Bentzen K, Norn S, Stahl Skov P, Pedersen M, Permin H. Cytokines modulate IgE-mediated histamine liberation from human basophils. Agents Actions 1992; Special Conference Issue: 260-4.
4. Gibbs BF, Noll T, Falcone FH, Haas H, Vollmer E, Vollrath I, et al. A three-step procedure for the purification of human basophils from buffy coat blood. Inflamm Res 1997; 46: 137-42.
5. Krieger M, von Tscharner V, Dahinden CA. Signal transduction for interleukin-3-dependent leukotriene synthesis in normal human basophils: opposing role of tyrosine kinase and protein kinase C. Eur J Immunol 1992; 22: 2907-13.
6. Wolfreys K, Oliveira DB. Alterations in intracellular reactive oxygen species generation and redox potential modulate mast cell function. Eur J Immunol 1997; 27: 297-306.
7. Gillissen A, Scharling B, Jaworska M, Bartling A, Rasche K, Schultze-Werninghaus G. Oxidant scavenger function of ambroxol in vitro: a comparison with N-acetylcysteine. Res Exp Med Berl 1997; 96: 389-98.