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Volumn 19, Issue 1 I, 1999, Pages 21-34

Trovafloxacin: An overview

Author keywords

[No Author keywords available]

Indexed keywords

ALATROFLOXACIN; ALUMINUM MAGNESIUM HYDROXIDE; ANTACID AGENT; CEFTAZIDIME; CIPROFLOXACIN; CLINAFLOXACIN; CLINDAMYCIN; DALFOPRISTIN PLUS QUINUPRISTIN; FERROUS SULFATE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; LOMEFLOXACIN; MEROPENEM; METRONIDAZOLE; MORPHINE; OFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; SUCRALFATE; TEICOPLANIN; TOBRAMYCIN; TROVAFLOXACIN; VANCOMYCIN;

EID: 0032950644     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.19.1.21.30507     Document Type: Review
Times cited : (38)

References (67)
  • 1
    • 0030757351 scopus 로고    scopus 로고
    • The chemistry and biological profile of trovafloxacin
    • Blighty KE, Gootz TD. The chemistry and biological profile of trovafloxacin. J Antimicrob Chemother 1997;36(suppl B):1-14.
    • (1997) J Antimicrob Chemother , vol.36 , Issue.SUPPL. B , pp. 1-14
    • Blighty, K.E.1    Gootz, T.D.2
  • 2
    • 0344436094 scopus 로고
    • 7-(3-azabicycb[3.1.0]hexy)quinolone antibacterial agents: Synthesis and biological evaluation resulting in identification of CP-99,219
    • New Orleans. Washington, DC: American Society for Microbiology
    • Brighty KE, Gootz TD, Girard TD, et al. 7-(3-azabicycb[3.1.0]hexy)quinolone antibacterial agents: synthesis and biological evaluation resulting in identification of CP-99,219 [abstr]. In: Programs and abstracts of the 33rd interscience conference on antimicrobial agents and chemotherapy, New Orleans. Washington, DC: American Society for Microbiology, 1993.
    • (1993) Programs and Abstracts of the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Brighty, K.E.1    Gootz, T.D.2    Girard, T.D.3
  • 3
    • 0030028529 scopus 로고    scopus 로고
    • Determination of trovafloxacin, a new quinolone antibiotic, in biological samples by reversed-phase high-performance liquid chromatography
    • Teng R, Tensfeldt TG, Liston TE, Foulds G. Determination of trovafloxacin, a new quinolone antibiotic, in biological samples by reversed-phase high-performance liquid chromatography. J Chromatogr B Biomed Appl 1996;675:53-9.
    • (1996) J Chromatogr B Biomed Appl , vol.675 , pp. 53-59
    • Teng, R.1    Tensfeldt, T.G.2    Liston, T.E.3    Foulds, G.4
  • 5
    • 0029043097 scopus 로고
    • Analysis of gyrA and grIA mutations in stepwise-selected ciprofloxacin-resistant mutants of Stapylococcus aureus
    • Ferrero L, Cameron B, Crouzet J. Analysis of gyrA and grIA mutations in stepwise-selected ciprofloxacin-resistant mutants of Stapylococcus aureus. Antimicrob Agents Chemother 1995;39:1554-8.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1554-1558
    • Ferrero, L.1    Cameron, B.2    Crouzet, J.3
  • 6
    • 0030801091 scopus 로고    scopus 로고
    • Postantibiotic effect of trovafloxacin on Pseudomonas aeruginosa
    • Boswell FJ, Andrews JM, Wise R. Postantibiotic effect of trovafloxacin on Pseudomonas aeruginosa. J Antimicrob Chemother 1997;39:811-14.
    • (1997) J Antimicrob Chemother , vol.39 , pp. 811-814
    • Boswell, F.J.1    Andrews, J.M.2    Wise, R.3
  • 7
    • 0030756869 scopus 로고    scopus 로고
    • Time-kill study of the activity of trovafloxacin compared with ciprofloxacin, sparfloxacin, metronidazole, cefoxitin, piperacillin and piperacillin/tazobactam against six anaerobes
    • Spangler SK, Jacobs MR, Appelbaum PC. Time-kill study of the activity of trovafloxacin compared with ciprofloxacin, sparfloxacin, metronidazole, cefoxitin, piperacillin and piperacillin/tazobactam against six anaerobes.J Antimicrob Chemother 1997;39(suppl B):23-7.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 23-27
    • Spangler, S.K.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 8
    • 0030814012 scopus 로고    scopus 로고
    • In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis
    • Brueggemann AB, Kugler KC, Doern GV. In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob Agents Chemother 1997;41(7):1594-7.
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.7 , pp. 1594-1597
    • Brueggemann, A.B.1    Kugler, K.C.2    Doern, G.V.3
  • 9
    • 0028959793 scopus 로고
    • Activity of CP 99,219 compared with DU-6859a, ciprofloxacin, ofloxacin, levofloxacin, lomefloxacin, tosufloxacin, sparfloxacin and grepafloxacin against penicillin-susceptible and -resistant pneumococci
    • Pankuch GA, Jacobs MR, Appelbaum PC. Activity of CP 99,219 compared with DU-6859a, ciprofloxacin, ofloxacin, levofloxacin, lomefloxacin, tosufloxacin, sparfloxacin and grepafloxacin against penicillin-susceptible and -resistant pneumococci. J Antimicrob Chemother 1995;35:230-2.
    • (1995) J Antimicrob Chemother , vol.35 , pp. 230-232
    • Pankuch, G.A.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 10
    • 0030820653 scopus 로고    scopus 로고
    • In-vitro and in-vivo activity of trovafloxacin against Streptococcus pneumoniae
    • Klugman KP, Gootz TD. In-vitro and in-vivo activity of trovafloxacin against Streptococcus pneumoniae. J Antimicrob Chemother 1997;39(suppl B):51-5.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 51-55
    • Klugman, K.P.1    Gootz, T.D.2
  • 11
    • 0030757121 scopus 로고    scopus 로고
    • In-vitro activity of trovafloxacin against sensitive and resistant aerobic bacteria using standard microdilution broth method and etest
    • Dembry LM, Farrel PA, Orcutt DR, Gerrity LA, Andriole VT. In-vitro activity of trovafloxacin against sensitive and resistant aerobic bacteria using standard microdilution broth method and Etest. J Antimicrob Chemother 1997;39(suppl B):35-42.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 35-42
    • Dembry, L.M.1    Farrel, P.A.2    Orcutt, D.R.3    Gerrity, L.A.4    Andriole, V.T.5
  • 12
  • 13
    • 0030790014 scopus 로고    scopus 로고
    • In-vitro activity of trovafloxacin, a new fluoroquinolone, against recent clinical isolates
    • Felmingham D, Robbins MJ, Ingley K, et al. In-vitro activity of trovafloxacin, a new fluoroquinolone, against recent clinical isolates. J Antimicrob Chemother 1997;39(suppl B):43-9.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 43-49
    • Felmingham, D.1    Robbins, M.J.2    Ingley, K.3
  • 14
    • 0030951636 scopus 로고    scopus 로고
    • Comparative in-vitro activities of RP59500 (quinupristin/dalfopristin), CL 329,998, CL 331,002, trovafloxacin, clinafloxacin, teicoplanin and vancomycin against gram-positive bacteria
    • Shonekan D, Handwerger S, Mildvan D. Comparative in-vitro activities of RP59500 (quinupristin/dalfopristin), CL 329,998, CL 331,002, trovafloxacin, clinafloxacin, teicoplanin and vancomycin against gram-positive bacteria. J Antimicrob Chemother 1997;39:405-9.
    • (1997) J Antimicrob Chemother , vol.39 , pp. 405-409
    • Shonekan, D.1    Handwerger, S.2    Mildvan, D.3
  • 15
    • 0031001953 scopus 로고    scopus 로고
    • Comparative in vitro activities of trovafloxacin (CP-99,219) against 445 gram-postive isolates from patients with endocarditis and those with other bloodstream infections
    • Endtz HP, Mouton JW, Den Hollander JG, Van Den Braak N, Verbrugh HA. Comparative in vitro activities of trovafloxacin (CP-99,219) against 445 gram-postive isolates from patients with endocarditis and those with other bloodstream infections. Antimicrob Agents Chemother 1997;41(5):1146-9.
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.5 , pp. 1146-1149
    • Endtz, H.P.1    Mouton, J.W.2    Den Hollander, J.G.3    Van Den Braak, N.4    Verbrugh, H.A.5
  • 16
    • 0030723853 scopus 로고    scopus 로고
    • Comparative in vitro activity and killing effect of trovafloxacin, DU-6859a, levofloxacin, and sparfloxacin against Staphylococcus aureus. Focus on methicillin-resistant isolates
    • Giamarellos-Bourboulis EJ, Grecka R, Galani I, Giamarellou H. Comparative in vitro activity and killing effect of trovafloxacin, DU-6859a, levofloxacin, and sparfloxacin against Staphylococcus aureus. Focus on methicillin-resistant isolates. Clin Drug Invest 1997;14(4):330-6.
    • (1997) Clin Drug Invest , vol.14 , Issue.4 , pp. 330-336
    • Giamarellos-Bourboulis, E.J.1    Grecka, R.2    Galani, I.3    Giamarellou, H.4
  • 17
    • 0029819239 scopus 로고    scopus 로고
    • In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidis
    • Mulazimoglu L, Drenning SD, Yu VL. In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob Agents Chemother 1996;40(10):2428-30.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.10 , pp. 2428-2430
    • Mulazimoglu, L.1    Drenning, S.D.2    Yu, V.L.3
  • 18
    • 0030877795 scopus 로고    scopus 로고
    • Antibacterial activity of trovafloxacin against nosocomial gram-positive and gram-negative isolates
    • Cunha BA, Hussain Qadri SM, Ueno Y, Walters EA, Domenico P. Antibacterial activity of trovafloxacin against nosocomial gram-positive and gram-negative isolates. J Antimicrob Chemother 1997;39(suppl B):29-34.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL B , pp. 29-34
    • Cunha, B.A.1    Hussain Qadri, S.M.2    Ueno, Y.3    Walters, E.A.4    Domenico, P.5
  • 20
    • 0030863172 scopus 로고    scopus 로고
    • Comparative in vitro activities of trovafloxacin (CP-99,219) against 221 aerobic and 217 anaerobic bacteria isolated from patients with intraabdominal infections
    • Citron DM, Appleman MD. Comparative in vitro activities of trovafloxacin (CP-99,219) against 221 aerobic and 217 anaerobic bacteria isolated from patients with intraabdominal infections. Antimicrob Agents Chemother 1997;41(10): 2312-16.
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.10 , pp. 2312-2316
    • Citron, D.M.1    Appleman, M.D.2
  • 21
    • 0030005618 scopus 로고    scopus 로고
    • In vitro activities of quinolones, β-lactams, tobramycin, and trimethoprim-sulfamethoxazole against nonfermentative gram-negative bacilli
    • Fass RJ, Barnishan J, Solomon MC, Ayers LW. In vitro activities of quinolones, β-lactams, tobramycin, and trimethoprim-sulfamethoxazole against nonfermentative gram-negative bacilli. Antimicrob Agents Chemother 1996;40(6):1412-18.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.6 , pp. 1412-1418
    • Fass, R.J.1    Barnishan, J.2    Solomon, M.C.3    Ayers, L.W.4
  • 22
    • 0029807636 scopus 로고    scopus 로고
    • In vitro susceptibility of anaerobes to quinolones in the United States
    • Hecht DW, Wexler HM. In vitro susceptibility of anaerobes to quinolones in the United States. Clin Infect Dis 1996;23(suppl 1):S2-8.
    • (1996) Clin Infect Dis , vol.23 , Issue.SUPPL. 1
    • Hecht, D.W.1    Wexler, H.M.2
  • 24
    • 0029807638 scopus 로고    scopus 로고
    • Comparison of activities of trovafloxacin (CP-99,219) and five other agents against 585 anaerobes with use of three media
    • Hecht DW, Osmolski JR. Comparison of activities of trovafloxacin (CP-99,219) and five other agents against 585 anaerobes with use of three media. Clin Infect Dis 1996;23(suppl 1):S44-50.
    • (1996) Clin Infect Dis , vol.23 , Issue.SUPPL. 1
    • Hecht, D.W.1    Osmolski, J.R.2
  • 28
    • 0028233239 scopus 로고
    • Mechanisms of quinolone resistance
    • Wiedemann B, Heisig P. Mechanisms of quinolone resistance. Infection 1994;22(suppl 2):S73-9.
    • (1994) Infection , vol.22 , Issue.SUPPL. 2
    • Wiedemann, B.1    Heisig, P.2
  • 29
    • 0029834825 scopus 로고    scopus 로고
    • Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase intravenous mutants of Streptococcus pneumoniae selected in vitro
    • Gootz, TD, Zaniewski R, Haskell S, et al. Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase intravenous mutants of Streptococcus pneumoniae selected in vitro. Antimicrob Agents Chemother 1996;40(12):2691-7.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.12 , pp. 2691-2697
    • Gootz, T.D.1    Zaniewski, R.2    Haskell, S.3
  • 30
    • 0030793087 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of trovafloxacin in healthy male volunteers after administration of single intravenous doses of prodrug, alatrofloxacin
    • Vincent J, Venitz J, Teng R, Baris BA, Willavize SA, Polzer RJ. Pharmacokinetics and safety of trovafloxacin in healthy male volunteers after administration of single intravenous doses of prodrug, alatrofloxacin. J Antimicrob Chemother 1997;39(suppl B):75-80.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 75-80
    • Vincent, J.1    Venitz, J.2    Teng, R.3    Baris, B.A.4    Willavize, S.A.5    Polzer, R.J.6
  • 31
    • 0029941236 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers
    • Teng R, Liston TE, Harris SC. Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers. J Antimicrob Chemother 1996;37:955-63.
    • (1996) J Antimicrob Chemother , vol.37 , pp. 955-963
    • Teng, R.1    Liston, T.E.2    Harris, S.C.3
  • 34
    • 0030805572 scopus 로고    scopus 로고
    • Oral bioavailability of trovafloxacin with and without food in healthy volunteers
    • Teng R, Dogolo LC, Willavize SA, Friedman HL, Vincent J. Oral bioavailability of trovafloxacin with and without food in healthy volunteers. J Antimicrob Chemother 1997;39(suppl B):87-92.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 87-92
    • Teng, R.1    Dogolo, L.C.2    Willavize, S.A.3    Friedman, H.L.4    Vincent, J.5
  • 35
    • 0030064142 scopus 로고    scopus 로고
    • Pharmacokinetics and penetration into inflammatory fluid of trovafloxacin (CP-99,219)
    • Wise R, Mortiboy D, Child J, Andrews JM. Pharmacokinetics and penetration into inflammatory fluid of trovafloxacin (CP-99,219). Antimicrob Agents Chemother 1996;40(1):47-9.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.1 , pp. 47-49
    • Wise, R.1    Mortiboy, D.2    Child, J.3    Andrews, J.M.4
  • 37
    • 0028140067 scopus 로고
    • The comparative pharmacokinetics and tissue penetration of single dose ciprofloxacin 400 mg i.v. and 750 mg p.o
    • Catchpole C, Andrews JM, Woodcock J, Wise R. The comparative pharmacokinetics and tissue penetration of single dose ciprofloxacin 400 mg i.v. and 750 mg p.o. J Antimicrob Chemother 1994;33:103-10.
    • (1994) J Antimicrob Chemother , vol.33 , pp. 103-110
    • Catchpole, C.1    Andrews, J.M.2    Woodcock, J.3    Wise, R.4
  • 39
    • 0029144805 scopus 로고
    • The invitro activity of CP-99,219, a new naphthyridone antimicrobial: A comparison with fluoroquinolone agents
    • Child J, Boswell F, Brenwald N, Andrews JM, Wise R. The invitro activity of CP-99,219, a new naphthyridone antimicrobial: a comparison with fluoroquinolone agents. J Antimicrob Chemother 1995;35:869-76.
    • (1995) J Antimicrob Chemother , vol.35 , pp. 869-876
    • Child, J.1    Boswell, F.2    Brenwald, N.3    Andrews, J.M.4    Wise, R.5
  • 40
    • 0030738989 scopus 로고    scopus 로고
    • Concentrations of irovafloxacin in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum after administration of single or multiple oral does to patients undergoing fiber-optic bronchoscopy
    • Andrews JM, Honeybourne D, Brenwald NP, et al. Concentrations of irovafloxacin in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum after administration of single or multiple oral does to patients undergoing fiber-optic bronchoscopy. J Antimicrob Chemother 1997;39:797-802.
    • (1997) J Antimicrob Chemother , vol.39 , pp. 797-802
    • Andrews, J.M.1    Honeybourne, D.2    Brenwald, N.P.3
  • 41
    • 0020679387 scopus 로고
    • In vitro activity of Bay 08967, a new quinolone derivative, compared with those of other antimicrobial agents
    • Wise R, Andrews JM, Edwards LJ. In vitro activity of Bay 08967, a new quinolone derivative, compared with those of other antimicrobial agents. Antimicrob Agents Chemother 1983;23:559-64.
    • (1983) Antimicrob Agents Chemother , vol.23 , pp. 559-564
    • Wise, R.1    Andrews, J.M.2    Edwards, L.J.3
  • 42
    • 0023792798 scopus 로고
    • Evaluation of the penetration of ciprofloxacin and amoxycillin into the bronchial mucosa
    • Honeybourne D, Andrews JM, Ashby JP, Lodwick R, Wise R. Evaluation of the penetration of ciprofloxacin and amoxycillin into the bronchial mucosa. Thorax 1988;43:715-19.
    • (1988) Thorax , vol.43 , pp. 715-719
    • Honeybourne, D.1    Andrews, J.M.2    Ashby, J.P.3    Lodwick, R.4    Wise, R.5
  • 43
    • 0027486693 scopus 로고
    • Comparative bronchoalveolar concentrations of ciprofloxacin and lomefloxacin after oral administration
    • Baldwin DR, Wise R, Andrews JM, Gill M, Honeybourne D. Comparative bronchoalveolar concentrations of ciprofloxacin and lomefloxacin after oral administration. Respir Med 1993;87:595-601.
    • (1993) Respir Med , vol.87 , pp. 595-601
    • Baldwin, D.R.1    Wise, R.2    Andrews, J.M.3    Gill, M.4    Honeybourne, D.5
  • 44
    • 0026562766 scopus 로고
    • The distribution of temafloxacin in bronchial epithelial lining fluid, alveolar macrophages and bronchial mucosa
    • Baldwin DR, Wise R, Andrews JM, Ashby JP, Honeybourne D. The distribution of temafloxacin in bronchial epithelial lining fluid, alveolar macrophages and bronchial mucosa. Eur Respir J 1992;5:471-6.
    • (1992) Eur Respir J , vol.5 , pp. 471-476
    • Baldwin, D.R.1    Wise, R.2    Andrews, J.M.3    Ashby, J.P.4    Honeybourne, D.5
  • 45
    • 0030919183 scopus 로고    scopus 로고
    • Penetration of trovafloxacin into cerebrospinal fluid in humans after intravenous infusion of alatrofloxacin
    • Cutler NR, Vincent J, Jhee SS, et al. Penetration of trovafloxacin into cerebrospinal fluid in humans after intravenous infusion of alatrofloxacin. Antimicrob Agents Chemother 1997;41(6):1298-1300.
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.6 , pp. 1298-1300
    • Cutler, N.R.1    Vincent, J.2    Jhee, S.S.3
  • 48
    • 0030471095 scopus 로고    scopus 로고
    • Metabolism of trovafloxacin, a new quinolone antibiotic, in Sprague-Dawley rats and beagle dogs
    • Dalvie DK, Khosla N, Navetta A, Brighty KE. Metabolism of trovafloxacin, a new quinolone antibiotic, in Sprague-Dawley rats and beagle dogs. Drug Metab Dispos 1996;24:1231-40.
    • (1996) Drug Metab Dispos , vol.24 , pp. 1231-1240
    • Dalvie, D.K.1    Khosla, N.2    Navetta, A.3    Brighty, K.E.4
  • 49
    • 0030906391 scopus 로고    scopus 로고
    • Excretion and metabolism of trovafloxacin in humans
    • Deepak KD, Khosla N, Vincent J. Excretion and metabolism of trovafloxacin in humans. Drug Metab Dispos 1997;25(4):423-7.
    • (1997) Drug Metab Dispos , vol.25 , Issue.4 , pp. 423-427
    • Deepak, K.D.1    Khosla, N.2    Vincent, J.3
  • 50
    • 0345299215 scopus 로고    scopus 로고
    • The effect of varying degrees of renal impairment on the safety, toleration, and pharmacokinetics of trovafloxacin
    • Toronto, Ontario. Washington, DC: American Society for Microbiology
    • Taylor A, Swan S, Marbury T, et al. The effect of varying degrees of renal impairment on the safety, toleration, and pharmacokinetics of trovafloxacin [abstr]. In: Programs and abstracts of the 37th interscience conference on antimicrobial agents and chemotherapy, Toronto, Ontario. Washington, DC: American Society for Microbiology, 1997.
    • (1997) Programs and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Taylor, A.1    Swan, S.2    Marbury, T.3
  • 52
    • 0009648982 scopus 로고    scopus 로고
    • A double blind, randomized, multicenter study of nosocomial pneumonia (NOS) comparing trovafloxacin with ciprofloxacin ± clindamycin/metromdazole
    • Toronto, Ontario. Washington, DC: American Society for Microbiology
    • Graham DR, Klein T, Torres A, et al. A double blind, randomized, multicenter study of nosocomial pneumonia (NOS) comparing trovafloxacin with ciprofloxacin ± clindamycin/metromdazole [abstr]. In: Programs and abstracts of the 37th interscience conference on antimicrobial agents and chemotherapy, Toronto, Ontario. Washington, DC: American Society for Microbiology, 1997.
    • (1997) Programs and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Graham, D.R.1    Klein, T.2    Torres, A.3
  • 53
    • 0000478448 scopus 로고    scopus 로고
    • A double blind, randomized, multicenter, global study in hospitalized community acquired pneumonia (CAP) comparing trovafloxacin with ceftriaxone + erythromycin
    • Toronto, Ontario. Washington, DC: American Society for Microbiology
    • Niederman M, Traub S, Ellison WT, et al. A double blind, randomized, multicenter, global study in hospitalized community acquired pneumonia (CAP) comparing trovafloxacin with ceftriaxone + erythromycin [abstr]. In: Programs and abstracts of the 37th interscience conference on antimicrobial agents and chemotherapy, Toronto, Ontario. Washington, DC: American Society for Microbiology, 1997.
    • (1997) Programs and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Niederman, M.1    Traub, S.2    Ellison, W.T.3
  • 54
    • 0002909942 scopus 로고    scopus 로고
    • A double blind, randomized, multicenter study in ambulatory community acquired pneumonia (CAP) comparing trovafloxacin with clarithromycin
    • Toronto, Ontario. Washington, DC: American Society for Microbiology
    • Sullivan J, Gezon D, Hopkins W, et al. A double blind, randomized, multicenter study in ambulatory community acquired pneumonia (CAP) comparing trovafloxacin with clarithromycin [abstr]. In: Programs and abstracts of the 37th interscience conference on antimicrobial agents and chemotherapy, Toronto, Ontario. Washington, DC: American Society for Microbiology, 1997.
    • (1997) Programs and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Sullivan, J.1    Gezon, D.2    Hopkins, W.3
  • 55
    • 0031888780 scopus 로고    scopus 로고
    • Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea
    • Jones KB, Schwebke J, Thorpe EM Jr, et al. Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea. Am J Med 1998;104:28-32.
    • (1998) Am J Med , vol.104 , pp. 28-32
    • Jones, K.B.1    Schwebke, J.2    Thorpe E.M., Jr.3
  • 56
    • 0029948139 scopus 로고    scopus 로고
    • Doseranging study of CP-99,219 (trovafloxacin) for treatment of uncomplicated gonorrhea
    • Hook EW III, Pinson GB, Blalock CJ, Johnson RB. Doseranging study of CP-99,219 (trovafloxacin) for treatment of uncomplicated gonorrhea. Antimicrob Agents Chemother 1996;40(7):1720-1.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.7 , pp. 1720-1721
    • Hook E.W. III1    Pinson, G.B.2    Blalock, C.J.3    Johnson, R.B.4
  • 57
    • 0030800464 scopus 로고    scopus 로고
    • Trovafloxacin
    • Haria M, Lamb HM. Trovafloxacin. Drugs 1997;54(3):435-45.
    • (1997) Drugs , vol.54 , Issue.3 , pp. 435-445
    • Haria, M.1    Lamb, H.M.2
  • 59
    • 0343499888 scopus 로고    scopus 로고
    • Effect of trovafloxacin (CP-99,219) on the pharmacokinetics and pharmacodynamics of warfarin in healthy male subjects
    • New Orleans, September 15-18
    • Teng R, Apseloff G, Vincent J, et al. Effect of trovafloxacin (CP-99,219) on the pharmacokinetics and pharmacodynamics of warfarin in healthy male subjects [abstr]. Presented at the 36th interscience conference on antimicrobial agents and chemotherapy, New Orleans, September 15-18, 1996.
    • (1996) 36th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Teng, R.1    Apseloff, G.2    Vincent, J.3
  • 60
    • 24344462635 scopus 로고    scopus 로고
    • Effects of orally administered trovafloxacin on the steady-state pharmacokinetics of digoxin: Results of a double-blind, placebo-controlled, parallel-group study
    • Hong Kong, June 10-13
    • Patterson BE, Kleinermans D, Brown SJ, et al. Effects of orally administered trovafloxacin on the steady-state pharmacokinetics of digoxin: results of a double-blind, placebo-controlled, parallel-group study [abstr]. Presented at the 7th international congress on infectious diseases, Hong Kong, June 10-13, 1996.
    • (1996) 7th International Congress on Infectious Diseases
    • Patterson, B.E.1    Kleinermans, D.2    Brown, S.J.3
  • 61
    • 4243965434 scopus 로고    scopus 로고
    • The effect of steady-state trovafloxacin on the steady-state pharmacokinetics of caffeine in healthy subjects
    • New Orleans, September 15-18
    • Lebel M, Teng R, Dogolo LC, et al. The effect of steady-state trovafloxacin on the steady-state pharmacokinetics of caffeine in healthy subjects. Presented at the 36th interscience conference on antimicrobial agents and chemotherapy, New Orleans, September 15-18, 1996.
    • (1996) 36th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Lebel, M.1    Teng, R.2    Dogolo, L.C.3
  • 62
    • 0030893443 scopus 로고    scopus 로고
    • Phase I study of the effects of trovafloxacin (CP-99,219) on the pharmacokinetics of theophylline in healthy men
    • Dickens GR, Wermeling D, Vincent J. Phase I study of the effects of trovafloxacin (CP-99,219) on the pharmacokinetics of theophylline in healthy men. J Clin Pharmacol 1997;37:248-52.
    • (1997) J Clin Pharmacol , vol.37 , pp. 248-252
    • Dickens, G.R.1    Wermeling, D.2    Vincent, J.3
  • 63
    • 0030836478 scopus 로고    scopus 로고
    • Effect of trovafloxacin, a new fluoroquinolone antibiotic, on the steady-state pharmacokinetics of theophylline in healthy volunteers
    • Vincent J, Teng R, Dogolo LC, Willavize SA, Friedman HL. Effect of trovafloxacin, a new fluoroquinolone antibiotic, on the steady-state pharmacokinetics of theophylline in healthy volunteers, J Antimicrob Chemother 1997;39(suppl B):81-6.
    • (1997) J Antimicrob Chemother , vol.39 , Issue.SUPPL. B , pp. 81-86
    • Vincent, J.1    Teng, R.2    Dogolo, L.C.3    Willavize, S.A.4    Friedman, H.L.5
  • 65
    • 0042781058 scopus 로고    scopus 로고
    • An open, placebo-controlled, two way crossover study to investigate the effects of cimetidine on the steady-state pharmacokinetics of trovafloxacin
    • Hong Kong, June 10-13
    • Patterson BE, Pukins L, Oliver SJ, et al. An open, placebo-controlled, two way crossover study to investigate the effects of cimetidine on the steady-state pharmacokinetics of trovafloxacin [abstr]. Presented at the 7th international congress on infectious diseases, Hong Kong, June 10-13, 1996.
    • (1996) 7th International Congress on Infectious Diseases
    • Patterson, B.E.1    Pukins, L.2    Oliver, S.J.3
  • 66
    • 0344004869 scopus 로고    scopus 로고
    • Effect of sucralfate, calcium carbonate, and ferrous sulphate on the bioavailability of trovafloxacin
    • Hong Kong, June 10-13
    • Teng R, Dogolo LC, Willavize SA, et al. Effect of sucralfate, calcium carbonate, and ferrous sulphate on the bioavailability of trovafloxacin [abstr]. Presented at the 7th international congress on infectious diseases, Hong Kong, June 10-13, 1996.
    • (1996) 7th International Congress on Infectious Diseases
    • Teng, R.1    Dogolo, L.C.2    Willavize, S.A.3


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