Genes for human arylamine N-acetyltransferases in relation to loss of the short arm of chromosome 8 in bladder cancer

Pharmacogenetics

Volumn 9, Issue 1, 1999, Pages 1-8

  Thygesen, Peter ^a   Risch, Angela ^a   Stacey, Mike ^a   Fakis, Giannoulis ^a   Takle, Lindsay ^b   Knowles, Margaret ^b   Sim, Edith ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE;

ACETYLATOR PHENOTYPE; ARTICLE; BLADDER CANCER; CANCER GENETICS; CANCER SUSCEPTIBILITY; CAUCASIAN; CHROMOSOME 8P; CLINICAL ARTICLE; COSMID; CPG ISLAND; DNA POLYMORPHISM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENETIC MARKER; HETEROZYGOSITY LOSS; HUMAN; PRIORITY JOURNAL; PSEUDOGENE;

EID: 0032950482     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199902000-00001     Document Type: Article

References (39)

1. Ambrosone CB, Freudenhein JL, Graham S, Marshall JR, Vena JE, Brasure JR, Shields PG. Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms and breast cancer risk. JAMA 1996; 276:1494-1501.
2. Atequera F, Bird A. Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci U S A 1993; 90:11995-11999.
3. Badawi AF, Hirvonen A, Bell DA, Lang NP, Kadlubar FF. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. Cancer Res 1995; 55:5230-5237.
4. Blum M, Grant DM, McBride W, Heim M, Meyer UA. Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression. DNA Cell Biol 1990; 9:193-203.
5. Bookstein R, Levy A, MacGrogan D, Lewis TB, Weissenbach J, O'Connell P, Leach RJ. Yeast artificial chromosome and radiation hybrid map of loci in chromosome band 8p22, a common region of allelic loss in multiple human cancers. Genomics 1994; 24:317-324.
6. Brockmoller J, Cascorbi I, Kerb R, Roots I. Combined analysis of inherited polymorphisms in arylamine N-acetyl transferase 2, glulathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. Cancer Res 1996; 56:3915-3925.
7. Cartwright RA, Glasham RW, Rogers HJ, Ahmed RA, Hall DB, et al. The role of N-acetyltransferase phenotypes in bladder carcino-genesis: a pharmaco-genetic epidemiological approach to bladder cancer. Lancet 1982; ii:842-846.
8. Daly AK, Cholerton S, Armstrong M, Idle JR. Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility. Environ Health Perspect 1994; 102:55-61.
9. Deitz AC, Doll MA, Hein DW. A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1 ) alleles. Anal Biochem 1997; 253:219-224.
10. Doll MA, Jiang W, Deitz AC, Rustan RD, Hein DW. Identification of a novel allele at the human NAT1 acetyltransferase locus. Biochem. Biophys. Res. Commun. 1997; 233:584-591.
11. Doll R, Peto R, Wheatley K, Gray R, Sutherland I. Mortality in relation to smoking - 40 years observation on male British doctors. BMJ 1994; 309:901-911.
12. Farrington SM, Cunningham C, Boyle SM, Wyllie AH, Dunlop MG. Detailed physical and deletion mapping of 8p with isolation of YAC clones from tumour suppressor loci involved in colorectal cancer. Oncogene 1996; 12:1803-1808.
13. Franke S, Klawitz I, Schnakenberg E, Rommel B, van den Ven W, Bullerdiek J, Schloot W. Isolation and mapping of a cosmid clone containing the human NAT2 gene. Biochem Biophys Res Commun 1994; 199:52-55.
14. Fugiwara Y, Emi M, Ohata H, Kato Y, Nakajima T, Mori T, Nakamura Y. Evidence for the presence of two tumour suppressor genes on chromosome 8p for colorectal carcinoma. Cancer Res 1993; 53:1172-1174.
15. Grant DM, Hughes NC, Janezic SA, Goodfellow GH, Chen HJ, Gaedigk A, et al. Human acetyltransferase polymorphisms. Mutation Res 1997; 376:61-70.
16. Golka K, Prior V, Blaszkewicz M, Cascorbi I, Schops W, Kierfeld G, et al. Occupational history and genetic N-acetyltransferase polymorphism in urothelial cancer - patients of Leverkusen, Germany. Scand J Work Environ Health 1996; 22:332-338.
17. Gustafson CE, Wilson PJ, Lukeis R, Baker E, Woollatt E, Annab L, et al. Functional evidence for a colorectal cancer tumour suppressor gene at chromosome 8p22-23 by monochromosome transfer. Cancer Res 1996; 56:5238-5245.
18. Henning S, Cascorbi I, Munchow B, Jahnke V, Roots I. Association of arylamine N-acetyltransferase NAT1 and NAT2 genotypes to laryngeal cancer risk. Pharmacogenetics 1998 (submitted)
19. Hickman D, Sim E. N-acetyltransferase polymorphism. Comparison of genotype and phenotype. Biochem Pharmacol 1991; 42:1007-1014.
20. Hickman D, Risch A, Camilleri JP, Sim E. Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants. Pharmacogenetics 1992; 2:217-226.
21. Hickman D, Risch A, Buckle V, Spurr NK, Jeremiah SJ, McCarthy A, Sim E. Chromosomal localisation of human genes for arylamine N-acetyltransferase. Biochem J 1994; 297:441-445.
22. Hubbard AL, Harrison DJ, Moyes C, Wylie AH, Cunningham C, Mannion E, Smith CAD. N-acetyltransferase type 2 in colorectal cancer and selective retention in cancers with chromosome 8p deletions. Gut 1997; 41:229-234.
23. Knowles MA. Molecular genetics of bladder cancer. Brit J Urol 1995; 75 (suppl 1):57-66.
24. Knowles MA, Shaw ME, Proctor AJ. Deletion mapping of chromosome 8 in cancers of the urinary bladder using restriction fragment length polymorphism and microsatellite polymorphisms. Oncogene 1993; 8:1357-1364.
25. Leach RJ, Banga SS, Ben-Othame K, Chughtui S, Clarke R, Daiger SP, et al. Report of the third international workshop on human chromosome 8 mapping 1996. Cytogenet Cell Genet 1996; 75:71-84.
26. Matas N, Thygesen P, Stacey M, Risch A, Sim E. Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours. Cytogenet Cell Genet 1997; 77:290-295.
27. Mao L, Schoenberg MP, Scicchitano M, Erozan YS, Merlo A, Schwab D, Sidransky D. Molecular detection of primary bladder cancer by microsatellite analysis. Science 1996; 271:659-662.
28. Okkels H, Sigsgaard T, Wolf H, Autrup H. Arylamine N-acetyltransferase 1 (NAT1 ) and 2 (NAT2) polymorphisms and susceptibility to bladder cancer: the influence of smoking. Cancer Epidemiol Biomark Prevent 1997; 6:225-231.
29. Payton MA, Sim E. Genotyping human arylamine N-acetyltransferase type I (NAT1): the identification of two novel allelic variants. Biochem Pharmacol 1998; 55:361-366.
30. Probst-Hench NM, Haile RW, Li DS, Sakamoto GT, Louie AD, Lin BK, et al. Lack of assocation between the polyadenylation polymorphism in the NTAT1 (acetyltransferase 1) gene and colorectal adenomas. Carcinogenesis 1996; 17:2125-2129.
31. Risch A, Wallace DMA, Bathers S, Sim E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Hum Mol Genet 1995; 4:231-236.
32. Smelt VA, Mardon H, Sim E. Placental expression of arylamine N-acetyltransferases. Pharmacol Toxicol 1998; 83:149-153.
33. Smith G, Stanley LA, Sim E, Strange RC, Wolf CR. Metabolic polymorphisms and cancer susceptibility. Cancer Surveys 1995; 25:27-65.
34. Stacey M, Thygesen P, Stanley L, Matas N, Risch A, Sim E. Arylamine N-acetyltransferase as a potential biomarker in bladder cancer: fluorescent in situ hybridisation and immunochemical studies. Biomarkers 1996; 1:55-61.
35. Stanley LA, Coroncos E, Cuff R, Hickman D, Ward A, Sim E. Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder. J Histochem Cytochem 1996; 44:1059-1067.
36. Takle LA, Knowles MA. Deletion mapping implicates two tumour suppressor genes on chromosome 8p in the development of bladder cancer. Oncogene 1996; 12:1083-1087.
37. Valsis KP, Weber WW, Bell DA, Dupret JM, Evans DAP, Grant DM, et al. Nomenclature for arylamine N-acetyltransferases. Pharmacogenetics 1995; 5:1-17.
38. Wood S, Schertzer M, Drabkin H, Patterson P, Longmire J, Deaven L. Characterization of human chromosome 8 cosmid library constructed from flow-sorted chromosomes. Cytogenet Cell Genet 1992; 59:243-247.
39. Yaremko ML, Wasylyshyn ML, Paulus KL, Michelassi F, Westbrook CA. Deletion mapping reveals two regions of chromosome 8 allele loss in colorectal carcinomas. Genes Chrom Cancer 1994; 10:1-6.