MEC1 and MEC2: Two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformation

Leukemia Research

Volumn 23, Issue 2, 1999, Pages 127-136

  Stacchini, Alessandra ^a   Aragno, Michela ^a   Vallario, Antonella ^a   Alfarano, Alda ^a   Circosta, Paola ^a   Gottardi, Daniela ^a   Faldella, Alessandra ^a   Rege Cambrin, Giovanna ^a   Thunberg, Ulf ^b   Nilsson, Kenneth ^b   Caligaris Cappio, Federico ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Apoptosis; B chronic lymphocytic leukemia; Bcl 2; Cell lines; Epstein Barr virus; Prolymphocytic leukemia

Indexed keywords

CD18 ANTIGEN; CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; CD23 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; CYTOKINE; HERMES ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROTEIN BAX; PROTEIN BCL 2;

ALLELE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; CANCER CELL CULTURE; CELL TRANSFORMATION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROLYMPHOCYTE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CHROMOSOME ABERRATIONS; HUMANS; LEUKEMIA, B-CELL, CHRONIC; LEUKEMIA, PROLYMPHOCYTIC; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0032950122     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(98)00154-4     Document Type: Article

References (34)

1. Nilsson K. Human B-lymphoid cell lines. Human Cell. 5(1):1992;25.
2. Mohammad R.M., Mohamed A.N., Hamdan M.Y., Vo T., Chen B., Katato K. et al. Establishment of a human BCLL xenograft model: utility as a preclinical therapeutic. Leukemia. 10:1996;130.
3. Rickinson A.B., Finerty S., Epstein M.A. Interaction of Epstein-Barr virus with leukaemic B cells in vitro. I. Abortive infection and rare cell line establishment from chronic lymphocytic leukemic cells. Clin. Exp. Immunol. 50:1982;347.
4. Karande A., Fialkow P.J., Nilsson K., Povey S., Klein G., Najfeld V. et al. Establishment of a lymphoid cell line from leukemic cells of a patient with chronic lymphocytic leukemia. Int. J. Cancer. 26:1980;551.
5. Najfeld V., Fialkow P.J., Karande A., Nilsson K., Klein G., Penfold G. Chromosome analyses of lymphoid cell lines derived from patients with chronic lymphocytic leukemia. Int. J. Cancer. 26:1980;543.
6. Crescenzi M., Napolitano M., Carbonari M., Antonelli A., Petrinelli P., Gaetano C. et al. Establishment of a new Epstein-Barr virusimmortalized cell line from chronic lymphocytic leukemia with trisomy of chromosome 12 that produces monoclonal IgM against sheep RBC antigen. Blood. 71:1988;9.
7. Lewin N., Avila-Carino J., Minarovits J., Lennette E., Brautbar C., Mellstedt H et al. Detection of two Epstein-Barr virus (EBV) carrying leukemic cell clones in a patient with chronic lymphocytic. Int. J. Cancer. 61:1995;159.
8. Wendel-Hansen V., Sallstrom J., De Campos-Lima P.O., Kjellstrom G., Sandlund A., Siegbahn A. et al. Epstein-Barr virus (EBV) can immortalize B-CLL cells activated by cytokines. Leukemia. 8:1994;476.
9. Tatsumi E., Harada S., Bechtold T., Lipscomb H., Davis J., Kuszynski C. et al. In vitro infection of chronic lymphocytic leukemia cells by Epstein-Barr virus (EBV). Leuk. Res. 10:1986;167.
10. Melo J.V., Foroni L., Brito-Babapulle V., Luzzatto L., Catowsky D. The establishment of cell lines from chronic B cell leukaemias: Evidence of leukaemic origin by karyotypic abnormalities and Ig gene rearrangement. Clin. Exp. Immunol. 73:1988;23.
11. Walls E.V., Doyle M.G., Patel K.K., Allday M.J., Catowsky D., Crawford D.H. Activation and immortalization of leukaemic B cells by Epstein-Barr virus. Int. J. Cancer. 44:1989;846.
12. Rai K.R., Sawitsky A., Cronkite E.P., Chanana A.D., Levy R.N., Pasternack B.S. Clinical staging of chronic lymphocytic leukaemia. Blood. 46:1975;219.
13. Rozman C., Montserrat E. Chronic lymphocytic leukemia. New Engl. J. Med. 333:1995;1052.
14. Tomlinson I.M., Walte G., Marks J.D., Llewelyn M.B., Winter G. The repertoire of human germline VH sequences reveals groups of VH segments with different hipervariable loops. J. Mol. Biol. 227:1992;776.
15. Seabright M. A rapid banding technique for human chromosomes. Lancet ii;1971:971.
16. Lin J.C., Lin S.C., De B.K., Chan Wc., Evatt B.L. Precision of genotyping of Epstain-Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease. Blood. 81:1993;3372.
17. Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bc1-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609.
18. Boise L.H., Gonzales-Garc~a M., Postema C.E., Ding L., Lindstein T., Turka L.A. et al. Bcl-X, a bc1-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74:1993;597.
19. Kabat EA, Wu TT, Perry HM, Gottesmann KS, Foeller C. Sequences of proteins of immunological interest (ed 5). Washington DC, US Department of Health and Human Services, National Institute of Health, 1991.
20. Schena M., Larsson L.G., Gottardi D., Gaidano G.L., Carlsson M., Nilsson K. et al. Growth and differentiation-associated expression of bc1-2 in B-chronic lymphocytic leukemia cells. Blood. 79:1992;2981.
21. + B lymphocytes. A. Revi Immunol. 7:1989;513.
22. Dazzi F., D'Andrea E., Biasi G., De Silvestro G., Gaidano G., Schena M. et al. Failure of B cells of chronic lymphocytic leukemia in presenting soluble and alloantigens. Clin. Immunol. Immunopathol. 75:1995;26.
23. Freedman A.S., Freeman G., Horowitz J.C., Daley J., Nadler L.M. B7, a B-cell-restricted antigen that identifies preaactivated B cells. J. Immunol. 139:1987;3260.
24. Yang E., Korsmeyer S.J. Molecular thanatopsis: a discourse on the Bc12 family and cell death. Blood. 88:1996;386.
25. Pezzella F., Tse A.G.D., Cordell J.L., Pulford K.A.F., Gatter K.C., Mason D.Y. Expression of the bc1-2 oncogene protein is not specific for the 14;18 chromosomal translocation. Am. J. Pathol. 137:1990;225.
26. Hanada M., Delia D., Aiello A., Stadtmauer E., Reed J.C. Bc1-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood. 82:1993;1820.
27. Caligaris-Cappio F., Ghia P., Gottardi D., Parvis G., Gregoretti M.G., Nilsson K. et al. The role of BCL-2 in the natural history of B-chronic lymphocyticleukemia. Current Topics Microbiol. 182:1992;279.
28. Robertson L.E., Plunkett W., McConnell K., Keating M.J., McDonnell T.J. Bc1-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome. Leukemia. 10:1996;456.
29. + B cells the expression of BCL-2 gene family is shifted toward protection from apoptosis. Br. J. Haematol. 94:1996;612.
30. Konig A., Menzel T., Lynen S., Wrazel L., Rosen A., Al-Katib A. et al. basic fibroblast growth factor (bFGF) upregulates the expression of bc1-2 in B cell chronic lymphocytic leukemia cell liens resulting in delaying apoptosis. Leukemia. 11:1997;258.
31. Dyer M.J.S., Zani V.J., Lu W.Z., O'Byrne A., Mould S., Chapman R. et al. BCL2 translocations in leukemias of mature B cells. Blood. 83:1994;3682.
32. Mainou-Fowler T., Prentice A.G. Modulation of apoptosis by cytokines in B-cell chronic Iymphocytic leukemia. Leuk. Lymphoma. 21:1996;369.
33. Steube K.G., Jadau A., Teepe D., Drexler H.G. Expressione of bc1-2 mRNA and protein in leukemia-lymphoma cell lines. Leukemia. 9:1995;1841.
34. Henderson S., Rowe M., Gregory C., Croom-Carter D., Wang F., Longnecker R., Kieff E., Rickinson A. Induction of bc1-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell. 65:1991;1107.