Protein binding of piritramide: Influence of various protein concentrations and the postoperative acute phase response

European Journal of Clinical Pharmacology

Volumn 54, Issue 11, 1999, Pages 843-845

  Wiesner, G ^a   Gruber, M ^a   Wild, K ^a   Hoerauf, K ^b   Taeger, K ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Acute phase response; Piritramide; Protein binding

Indexed keywords

ALBUMIN; OROSOMUCOID; PIRITRAMIDE;

ADULT; ARTICLE; BINDING AFFINITY; DOSE RESPONSE; DRUG PROTEIN BINDING; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ACUTE-PHASE REACTION; ANALGESICS, OPIOID; BLOOD PROTEINS; HUMANS; MALE; OROSOMUCOID; PAIN, POSTOPERATIVE; PIRINITRAMIDE; POSTOPERATIVE PERIOD; PROTEIN BINDING; SERUM ALBUMIN; TIME FACTORS;

EID: 0032950042     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050564     Document Type: Article

References (12)

1. 1. Saarne A (1969) Clinical evaluation of the new analgesic piritramide. Acta Anaesthesiol Scand 13: 11-19
2. 2. Kay B (1971) A clinical investigation of piritramide in the treatment of postoperative pain. Br J Anaesth 43: 1167-1171
3. 3. Kietzmann D, Briede I, Bouillon T, Gundert-Remy U, Kettler D (1996) Pharmacokinetics of piritramide after an intravenous bolus in surgical patients. Acta Anaesthesiol Scand 40: 898-903
4. 4. Crockson RA, Payne CJ, Ratcliff AP, Soothill JF (1966) Time sequence of acute phase reactive proteins following surgical trauma. Clin Chim Acta 14: 435-441
5. 5. Aronsen KF, Ekelund G, Kindmark CO, Laurell CB (1972) Sequential changes of plasma proteins after surgical trauma. Scand J Clin Lab Invest Suppl 124: 127-136
6. 6. Wiesner G, Taeger K, Peter K (1996) Die Serumproteinbindung von Fentanyl. Einfluss der postoperativen Akut-Phase-Reaktion mit Anstieg von saurem alpha 1-Glykoprotein und methodische Probleme bei der Bestimmung mittels Gleichgewichtsdialyse. Anaesthesist 45: 323-329
7. 7. Michaelis HC, Kietzmann D, Neurath H, Jongepier U, Schilling B (1991) Sensitive determination of piritramide in human plasma by gas chromatography. J Chromatogr B Biomed Sci Appl 571: 257-262
8. 8. Kurz H, Trunk H, Weitz B (1977) Evaluation of methods to determine protein-binding of drugs. Equlibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration. Arzneimittelforschung 27: 1373-1380
9. 9. Meuldermans WE, Hurkmans RM, Heykants JJ (1982) Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and Iofentanil in blood. Arch Int Pharmacodyn Ther 257: 4-19
10. 10. Julius HC, Levine HL, Williams WD (1989) Meperidine binding to isolated alpha 1-acid glycoprotein and albumin. DICP 23: 568-572
11. 11. Kushner I (1982) The phenomenon of the acute phase response. Ann N Y Acad Sci 389: 39-48
12. 12. Fremstad D, Bergerud K, Haffner JFW, Lunde PKM (1976) Increased plasma binding of quinidine after surgery: a preliminary report. Eur J Clin Pharmacol 10: 441-444