Monoclonal antibodies against maternal major histocompatibility complex class I molecules induce rapid abortion in mice

American Journal of Reproductive Immunology

Volumn 41, Issue 3, 1999, Pages 217-223

  Knezevic, Nikola ^a,e   Nikolic, Boris ^b,e   Brajsa, Karmen ^c,e   Marusic, Suzana ^d,e   Spaventi, Radan ^c   Jonjic, Nives ^f   Jonjic, Stipan ^f  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c PLIVA Research Institute Ltd   (Croatia)

^d PFIZER INC   (United States)

^e Institute Ruder   (Croatia)

^f UNIVERSITY OF RIJEKA   (Croatia)

Author keywords

Abortion; MHC class I; Monoclonal antibodies; Placenta

Indexed keywords

FETAL ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; FEMALE; INDUCED ABORTION; MOUSE; NONHUMAN; PLACENTA; PREGNANCY; PRIORITY JOURNAL;

EID: 0032947972     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1999.tb00535.x     Document Type: Article

References (26)

1. Clark DA, McDermott M, Sczewzak MR: Impairment of host vs. graft reaction in pregnant mice. II. Selective suppression of cytotoxic cell generation correlates with soluble suppressor activity and with successful allogeneic pregnancy. Cell Immunol 1980; 52:106-111.
2. Clark DA: Contraversies in reproductive immunology. Crit Rev Immunol 1991; 11:215-247.
3. Chaouat G, Kolb J-P, Kiger N, Stanislawski M, Wegman TG: Immunologic consequences of vaccination against abortion in mice. J Immunol 1985; 134:1594-1598.
4. Zijlstra M, Bix M, Simister NE, Loring JM, Raulet DH, Jaenish R: β2-microglobulin deficient mice lack CD4-CD8+ cytotoxic T cells. Nature 1990; 344:742-746.
5. Grusby MJ, Randall SJ. Papaioannou VE, Glimcher LH: Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science 1991; 153:1417-1419.
6. Sargent IL, Wilkins T, Redman CWG: Maternal immune response to the fetus in early pregnancy and recurrent miscarriage. Lancet 1988; 2(8620):1099-1104.
7. Jazwinska EC, Kilpatrick DC, Smart GE, Liston WA: Feto - maternal HLA compatibility does not have a major influence on human pregnancy except for lymphocytotoxicity production. Clin Exp Immunol 1987; 68:116-122.
8. Carreras LO, Machin CJ, Defreyn G, Machin SJ, Vermylen J, Deman R, Spitz B, Van Assche A: Arterial thrombosis, intrauterine death and lupus anticoagulant detection of immunoglobulin interfering with prostacyclin formation. Lancet 1981; 1:244-246.
9. Prentice RL, Gatenby PA, Loblay RA, Shearman RP, Kronenberg H, Basten A: Lupus anticoagulant in pregnancy. Lancet 1984; 1:464.
10. Lockshin MD, Druzin ML, Goei S: Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosus. N Engl J Med 1985; 313:152-156.
11. Branch DW, Dudley DJ, Mitchel MD, Creighton KA, Abbott TM, Hammond EH, Daynes RA: Immunoglobulin G fraction from patients with antiphospholipid antibodies cause fetal death in Balb/c mice: A model for autoimmune fetal loss. Am J Obstet Gynecol 1990; 163:210-216.
12. Ozato K, Mayer NM, Sachs DH: Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 antigens. J Immunol 1980; 124:533-540.
13. Ozato K, Mayer MN, Sachs DH: Monoclonal antibodies to mouse major histocomatibility complex antigen. IV. A series of hybridoma clones producing anti-H2d antibodies and an examination of expression of H-2D antigens on the surface of these cells. Transplantation 1982; 34:113-120.
14. Nauciel C, Espinasse-Maes F: Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection. Infect Immunity 1992; 60:450-454.
15. Marusic-Galesic S, Stephany DA, Longo DL, Kruisbeek AM: Development of CD4-CD8+ cytotoxic T cells requires interaction with class I MHC molecules. Nature 1988; 333:180-182.
16. Gendron RL, Nestel FP, Lapp WS, Baines MG: Lipopolisaccharide-induced fetal resorption in mice is associated with the intrauterine production of tumor necrosis factor-alpha. J Reprod Fertil 1990; 90:395-402.
17. Pavic I, Polic B, Crnkovic I, Lucin P, Jonjic S, Koszinski UH: Participation of endogenous tumor necrosis factor alpha in host resistance to cytomegalovirus infection. J Gen Virol 1993; 74:2215-2223.
18. Chatterjee-Hasrouni S, Lala PK: Localization of H-2 antigens on mouse trophoblast cells. J Exp Med 1979; 149:1238-1255.
19. Lala PK, Chatterjee-Hasrouni S, Kearns M, Montgomery B, Calvicenzo V: Immunobiology of the feto -maternal interface. Immunol Rev 1983; 75:87-116.
20. Beer AE: Immunopathologic factors contributing to recurrent spontaneous abortion in humans. Am J Reprod Immunol 1983; 4:182-184.
21. Unander M, Olding LB: Habitual abortion: Parental sharing of HLA antigens, absence of maternal blocking antibody and suppression of maternal lymphocytes. Am J Reprod Immunol 1983; 4:171-178.
22. Petri M, Golbus M, Anderson R, Whiting-O'Keefe Q, Corash L, Hellman D: Antinuclear antibody, lupus anticoagulant, and anticardiolipin antibody in women with idiopathic habitual abortion: A controlled, prospective study of forty-four women. Arthritis Rheum 1987; 30:601-606.
23. Boddi M, Prisco D, Fedi S, Cellai AP, Liotta AA, Parretti E, Mecacci F, Mello G, Abbate R: Antiphospholipid antibodies and pregnancy disorders in women with insulin dependent diabetes. Thomb Res 1996; 82:207-216.
24. Festini MR, Limson GM, Marou T: Autoimmune causes of recurrent pregnancy loss. Kobe J Med Sci 1997; 43:143-157.
25. Miyatake T, Sato K, Takigami K, Koyamada N, Hancock WW, Bazin H, Latinne D, Bach FH, Soares MP: Complement-fixing elicited antibodies are a major component in the pathogenesis of xenograft rejection. J Immunol 1998; 160:4114-4123.
26. Bach FH, Robson SC, Ferran C, Winkler H, Millan MT, Stuhlmeier KM, Vanhove B, Blakely ML, van der Werf WJ, Hofer E, de Martin R, Hancock WW: Endothelial cell activation and thromboregulation during xenograft rejection. Immunol Rev 1994; 141:5-30.