A new method for the synthesis of normal and medium ring silylated unsaturated thiolactones

Synlett

Volumn , Issue 4, 1999, Pages 486-488

  Bonini, Bianca F ^a   Comes Franchini, Mauro ^a   Fochi, Mariafrancesca ^a   Mazzanti, Germana ^a   Ricci, Alfredo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

(Z) carboxy silyl Enethiols; Polyphosphate esters; Thiolactones; Carboxy acylsilanes

Indexed keywords

SUCCINIC ACID; THIOLACTONE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFORMATION; CYCLIZATION; DIMERIZATION; POLYMERIZATION; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS; TEMPERATURE DEPENDENCE;

EID: 0032947473     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-6182     Document Type: Article

References (31)

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21. General procedure for the preparation of 2: hydrogen chloride and hydrogen sulfide were bubbled into a solution of the CD-carboxy acylsilane 1 (1.0 mmol) in anhydrous diethyl ether (50 mL) at-20°C, until the starting acylsilane had disappeared (TLC with 1:1 light petroleum-diethyl ether as eluent). The mixture was allowed to warm to room temperature and solid sodium hydrogen carbonate was added to the solution until the evolution of carbon dioxide ceased (10 g), then the reaction was left overnight. The crude, filtered and concentrated under reduced pressure, gave the (Z)-ω-carboxy-α-silyl enethiol 2 in a pure form.
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25. 2Ph).
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