Failure of acute hyperinsulinemia to alter blood pressure is not due to baroreceptor feedback

American Journal of Hypertension

Volumn 12, Issue 4 I, 1999, Pages 405-413

  Richey, Joyce M ^b   Poulin, Renee A ^b   Buchanan, Thomas A ^b   Galperin, Edward ^b   Moore, Donna M ^b   Bergman, Richard N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE

Author keywords

Denervation; Dogs; Glucose metabolism

Indexed keywords

INSULIN; PHENYLEPHRINE;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; DENERVATION; DOG; FEEDBACK SYSTEM; GLUCOSE METABOLISM; HEART RATE; HYPERINSULINEMIA; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; VASODILATATION;

ACUTE DISEASE; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; CAROTID SINUS; DENERVATION; DOGS; FEEDBACK; GLUCOSE; HEART RATE; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INFUSIONS, INTRAVENOUS; INSULIN; LIVER; MALE; PRESSORECEPTORS;

EID: 0032946988     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(98)00272-6     Document Type: Article

References (38)

1. Modan M, Halkin H, Almog S, et al: Hyperinsulinemia. A link between hypertension, obesity and glucose intolerance. J Clin Invest 1985;75:809-914.
2. Muller DC, Ilahi D, Prtley RE, et al: An epidemiological test of the hyperinsulinemia hypertension hypothesis. J Clin Endocrinol Metab 1993;76:544-548.
3. Rowe JW, Young JB, Mimaker KL, et al: Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 1981;30:219-225.
4. Anderson EA, Hoffman RP, Balon TW, et al: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 1991; 87:2246-2252.
5. Landsberg L, Krieger DR: Obesity, metabolism and sympathetic nervous system. Am J Hypertens 1989;2: 125S-132S.
6. Brands MW, Mizelle HL, Gaillard CA, et al: The hemodynamic response to chronic hyperinsulinemia in conscious dogs. Am J Hypertens 1991;4:164-168.
7. Hall JE, Coleman TG, Mizelle HL, Smith MJ: Chronic hyperinsulinemia and blood pressure regulation? Am J Physiol 1990;258 (Renal Fluid Electrolyte Physiol. 27): F722-F731.
8. Hall JE, Coleman TG, Mizelle HL, Smith MJ: Chronic hyperinsulinemia and blood pressure regulation? Am J Physiol 1990;258 (Renal Fluid Electrolyte Physiol. 27): F722-F731.
9. Cowley AW Jr, Liard JF, Guyton AC: Role of baroreceptor reflex in daily control of arterial blood pressure and other variables in dogs. Circ Res 1973;24:554-576.
10. Ferrario CM, McCubbin JW, Page IH: Hemodynamic characteristics of chronic experimental neurogenic hypertension in unanesthetized dogs. Circ Res 1969;4: 911-922.
11. Alper RH, Jacob HJ, Brody MJ: Regulation of arterial pressure lability following sino-aortic deafferentation in rats. Am J Physiol 1987;253:H466-H467.
12. Barron K, Trapani A, Gordon F, Brody M: Baroreceptor denervation profoundly enhances cardiovascular responses to central angiotensin II. Am J Physiol 1989;257 (Heart Circ Physiol 26):H314-H323.
13. Barron K, Trapani A, Gordon F, Brody M: Baroreceptor denervation profoundly enhances cardiovascular responses to central angiotensin II. Am J Physiol 1989;257 (Heart Circ Physiol 26):H314-H323.
14. Broten TP, Zehr JE: Baroreflex modulation of ultradian oscillations of blood pressure and heart rate in unanesthetized dogs. Chronobiologia 1988;16:241-255.
15. Pacini G, Bergman RN: PACBERG: an adaptive program for controlling the blood sugar. Comput Progr Biomed 1983;16:13-20.
16. Somogyi M: Determination of blood sugar. J Biol Chem 1945;160:69-73.
17. Herbert V, Law K, Gottlieb C, Bleicher S: Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab 1965;25:1375-1384.
18. Finegood DT, Bergman RN, Vranic M: Estimation of endogenous glucose production during hyperinsulinemic euglycemic glucose clamps: comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 1987;36:914-924.
19. Bradley DC, Steil GM, Bergman RN: OOPSEG: a data smoothing program for quantitation and isolation of random measurement error. Computer Meth Prog Biomed 1995;46:67-77.
20. Finegood DT, Bergman RN: Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol 1983;244:E472-E479.
21. Berne D, Fagius J, Pollare T, Hjemdahl P: The sympathetic response to euglycemic hyperinsulinemia. Diabetologia 1992;35:873-879.
22. Porcellati F, Fanelli C, Bottini P, et al: Mechanisms of arterial hypotension after therapeutic dose of subcutaneous insulin in diabetic autonomic neuropathy. Diabetes 1993;42:1055-1064.
23. DeFronzo RA, Cooke CR, Andes R, et al: The effect of insulin on renal handling of sodium, calcium and phosphate in man. J Clin Invest 1976;55:845-855.
24. Steinberg HO, Brechtel G, Johnson A, et al: Insulin mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 1994;94:1172-1179.
25. 2+ ATPase. Am J Hypertens 1992;5:637-641.
26. Alexander MB, Oake RJ: The effect of insulin on vascular reactivity to norepinephrine. Diabetes 1977;26: 611-614.
27. Hall JE, Brands MW, Kivlighn SD, et al: Chronic hyperinsulinemia and blood, interaction with catecholamines? Hypertension 1990;15:519-527.
28. Liang CS, Doherty JU, Faillace R, et al: Insulin infusion in conscious dogs: effects on systemic and coronary hemodynamics, regional blood flows and plasma catecholamines. J Clin Invest 1982;69:1321-1336.
29. Julius S, Gudbrandsson T, Jamerson K, et al: The hemodynamic link between insulin resistance and hypertension. J Hypertens 1991;9:983-986.
30. Ito CS, Scher AM: Hypertension following arterial baroreceptor denervation in the unanesthetized dog. Circ Res 1981;48:576-586.
31. Franchini KG, Krieger EM: Carotid chemoreceptors influence arterial pressure in intact and aortic-denervated rats. Am J Physiol 1992;262 (Regulatory Integrative Comp Physiol 31):R677-R683.
32. Franchini KG, Krieger EM: Carotid chemoreceptors influence arterial pressure in intact and aortic-denervated rats. Am J Physiol 1992;262 (Regulatory Integrative Comp Physiol 31):R677-R683.
33. Sauter A, Goldstein M, Engel J, Ueta K: Effect of insulin on central catecholamines. Brain Res 1983;260:330-333.
34. Page MM, Watkins PJ: Provocation of postural hypotension by insulin in diabetic autonomic neuropathy. Diabetes 1976;25:90-95.
35. Lembo G, Napoli R, Capaldo B, Rendina V: Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension. J Clin Invest 1992;90:24-29.
36. Miles DW, Hayter CJ: The effect of intravenous insulin on the circulatory responses to tilting in normal and diabetic subjects with special reference to baroreceptor reflex block and atypical hypoglycemic reactions. Clin Sci 1968;34:419-430.
37. Laakso M, Edelman V, Brechtel G, Baron AD: Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. J Clin Invest 1990;85:1844-1852.
38. Allison SP, Tomlin PJ, Chamberlain MJ: Some effects of anesthesia and surgery on carbohydrate and fat metabolism. Br J Anaesth 1987;41:588-592.