Chloroquine- and chlorphentermin-induced lipidosis in rat retina;Chloroquin und chlorphentermin induzierte lipidose der rattenretina

Klinische Monatsblatter fur Augenheilkunde

Volumn 214, Issue 3, 1999, Pages 178-182

  Bredehorn, Timm ^a   Duncker, Gernot I W ^a  

^a Martin LutherUniversität Halle Wittenberg   (Germany)

Author keywords

Amphiphilic drugs; Chloroquine; Chlorphentermine; Electroretinogram; Lipidosis; Photoreceptor cell degeneration; Rat retina

Indexed keywords

CHLOROQUINE; CHLORPHENTERMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; ELECTRORETINOGRAM; FEMALE; LIPID STORAGE; LIPIDOSIS; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; RAT; RETINA DEGENERATION;

EID: 0032946758     PISSN: 00232165     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1034772     Document Type: Conference Paper

References (17)

1. Bernstein HN, Ginsberg J. The pathology of chloroquine retinopathy. Arch Ophthalmol (Chicago) 1964; 71:238-245
2. Bredehorn T, Duncker G, Kuper H, Papst N. A new system for recording electroretinographical potentials in animals. Ophthalmologica 1994; 208:98-104
3. Duncker G, Bredehorn T. Chlorphentermine-induced lipidosis in the rat retina: a functional and morphologi-cal study. Albrecht von Graefes Arch Klin Exp Ophthalmol 1994; 232:368-372
4. Duncker G, Schmiederer M, Bredehorn T. Chloroquine-induced lipidosis in rat retina: A functional and morphological study. Ophthalmologica 1995; 209:79-83
5. Gouras P. Electroretinography: some basic principles. Invest Ophthalmol 1970; 9:557-569
6. Gregory MH, Rutty DA, Wood RD. Differences in retinotoxic action of chloroquine and phenothiazine derivates. J Pathol 1970; 120:139-150
7. Hallberg A, Naeser P, Andersson A. Effects of long-term chloroquine exposure on the phospholipid metabolism in the retina and pigment epithelium of the mouse. Acta Ophthalmologica 1990; 68:125-130
8. Hennekes R. Klinische Elektroretinographie. Fortschr Ophthalmol 1989; 86:146-150
9. Ivanina TA, Zueva MV, Lebedeva MN, Bogoslovsky AI, Bunin AJ. Ultrastructural alterations in rat and cat retina and pigment epithelium induced by chloroquine. Albrecht von Graefes Arch Klin Exp Ophthalmol 1983; 220:32-38
10. Lehnen W, Wünsche H. Das Elektroretinogramm in verschiedenen Lebensaltern. Albrecht von Graefes Arch Klin Exp Ophthalmol 1966; 170:147-155
11. Lüllmann H, Lüllmann-Rauch R, Wassermann O. Lipidosis induced by amphiphilic cationic drugs. Biochemical Pharmacology 1978; 27:1103-1108
12. Lüllmann-Rauch R. Experimentally induced lipidosis in rat retinal pigment epithelium. Albrecht von Graefes Arch Klin Exp Ophthalmol 1981; 215:297-303
13. Lüllmann-Rauch R, Lüpkes S. Drug-induced degeneration of photoreceptor cells. Adv Biosci 1987; 62:471-476
14. Lüpkes S. Retinopathie bei Ratten nach oraler Behandlung mit Tiloron und Chloroquin. Med Diss Kiel, 1990
15. Marmor MF, Arden GB, Nilsson SFG, Zrenner E. Standard for clinical electroretinography. Arch Ophthalmol 1989; 107:816-819
16. Schaeppi U, Krinke G, Fink X, Hofer R, Duennenberger D. Electroretinography in rats. Agents Actions 1988; 24:395-402
17. Wetterholm DH, Winter FC. Histopathology of chloroquine retinal toxicity. Arch Ophthalmol (Chicago) 1964; 71:82-87