Medical therapy of achalasia: A benefit reserved for few

Digestion

Volumn 60, Issue 1, 1999, Pages 11-16

  Bortolotti, Mauro ^a  

^a NONE   (Italy)

Author keywords

Achalasia; Dysphagia; Esophagus; Nifedipine; Nitroderivatives

Indexed keywords

NIFEDIPINE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG TOLERABILITY; DYSPHAGIA; ESOPHAGOGRAPHY; ESOPHAGUS ACHALASIA; ESOPHAGUS DILATATION; ESOPHAGUS MANOMETRY; FEMALE; HEADACHE; HUMAN; HYPOTENSION; LOWER ESOPHAGUS SPHINCTER PRESSURE; MAJOR CLINICAL STUDY; MALE; PATIENT SELECTION; PRIORITY JOURNAL; REMISSION; SUBLINGUAL DRUG ADMINISTRATION; TACHYCARDIA; TREATMENT FAILURE; TREATMENT OUTCOME; VERTIGO;

ADMINISTRATION, SUBLINGUAL; DILATATION; ESOPHAGEAL ACHALASIA; ESOPHAGOGASTRIC JUNCTION; FEMALE; FOLLOW-UP STUDIES; HUMANS; ISOSORBIDE DINITRATE; MALE; MANOMETRY; MIDDLE AGED; NIFEDIPINE; PATIENT SELECTION; TIME FACTORS; TREATMENT OUTCOME;

EID: 0032946509     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007583     Document Type: Article

References (27)

1. Aggestrup S, Uddman R, Sundler F, et al: Lack of vasoactive intestinal peptide nerves in esophageal achalasia. Gastroenterology 1983; 84:924.
2. Smith B: The neurological lesion in achalasia of the cardia. Gut 1970;11:388.
3. Mearin F, Mourelle M, Guarner F. et al. Patients with achalasia lack nitric oxide synthase in the gastro-esophageal junction. Eur J Clin Invest 1993;23:724-728.
4. Janssens J, Sifrim D, Lerut A: Esophageal motility disorders: A pathophysiological concert (abstract). Gastroenterology 1995;108:621.
5. Di Martino N, Bortolotti M, Izzo G, et al: 24-hour ambulatory manometry in patients with achalasia of the esophagus. Dis Esophagus 1997;10:121-127.
6. Cassella RR, Brown AL, Sayre LJ, et al: Achalasia of the esophagus: Pathologic and etiologic considerations. Ann Surg 1964;160:474-486.
7. Ponce J, Miralbes M, Garrigues V, et al: Return of esophageal peristalsis after Heller's myotomy for idiopathic achalasia. Dig Dis Sci 1986; 31:545-547.
8. Mellow M: Return of esophageal peristalsis in idiopatic achalasia. Gastroenterology 1976;70: 1148-1151.
9. Coccia G, Bortolotti M, Michetti D, Dodero M: Return of esophageal peristalsis after nifedipine therapy in patients with idiopathic esophageal achalasia. Am J Gastroenterol 1992;87: 1705-1708.
10. Richter JE: Motility disorders of the esophagus; in Yamada T, Alpers DH, Owyang C, Powell DW, Silverstein FE (eds): Textbook of Gastroenterology ed 2. Philadelphia, Lippincott, 1995. p 1174.
11. Vantrappen G, Hellemans J: Treatment of achalasia and related motor disorders. Gastroenterology 1980;79:144-154.
12. Bortolotti M, Labò G: Clinical and manometric effects of nifedipine in patients with esophageal achalasia. Gastroenterology 1981;80:39-44.
13. Traube M, Dubovik S, Lange RC, et al: The role of nifedipine therapy in achalasia: Results of a randomized, double-blind, placebo controlled study. Am J Gastroenterol 1989;84: 1259-1262.
14. Coccia G, Bortolotti M, Michetti M, et al: Prospective clinical and manometric study comparing pneumatic dilatation and sublingual nifedipine in the treatment of oesophageal achalasia. Gut 1991;32:604-606.
15. Gelfond M, Rozen P. Gilat T: Isosorbide dinitrate and nifedipine treatment of achalasia: A clinical manometric and radionuclide evaluation. Gastroenterology 1982;83:963-969.
16. Bortolotti M, Coccia G, Brunelli F, et al: Isosorbide dinitrate of nifedipine: Which is preferable in the medical therapy of achalasia? Ital J Gastroenterol 1994;26:379-382.
17. Olsen AM: Study of esophageal motility in health disease. Ann Otol Rhinol Laryngol 1968;77:892-905.
18. Kelley ML Jr: Intraluminal manometry in the evaluation of malignant disease of the esophagus. Cancer 1968;21:1011-1018.
19. Schneider JH, Peters JH, Kirkman L, et al: Are the motility abnormalities of achalasia reversible? An experimental study (abstract). Gastroenterology 1996;110:1417.
20. Murad F: Drugs used for the treatment of angina: Organic nitrates, calcium channel blockers and β-adrenergic antagonists; in Goodman Gilman A, Rall TW, Nies AS, Taylor P (eds): Goodman & Gilman's. The Pharmacological Basis of Therapeutics, ed 8. New York, Pergamon Press 1990, pp 764-783.
21. MacKenzie J, Belch J, Land D, et al: Oesophageal ischemia in motility disorders associated with chest pain. Lancet 1988;ii:592-596.
22. Hukuhara T, Kotania S, Sato G: Effect of destruction of intramural ganglion cells on colon motility: Possible genesis of congenital mev gacolon. Jpn J Physiol 1961;11:635-640.
23. Piqué JM, Whittle BJR, Esplugues JV: The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation. Eur J Pharmacol 1989;174:293-296.
24. Chou CC, Alemayehu A: Peptidergic regulation of gastrointestinal blood flow; in Brown D (ed): Gastrointestinal Regulatory Peptides. Berlin, Springer, 1993, p 325.
25. Eckart V, Aignherr C, Bernhard G: Predictors of outcome in patients with achalasia treated by pneumatic dilation. Gastroenterology 1992; 103:1732-1738.
26. Parkman HP, Reynolds JC, Ouyang A, et al: Pneumatic dilatation or esophagomytomy treatment for idiopathic achalasia: Clinical outcomes and cost analysis. Dig Dis Sci 1993; 38:75-85.
27. Annese V, Basciani M, Perri F, et al: Controlled trial of botulinum toxin injection versus placebo and pneumatic dilation in achalasia. Gastroenterology 1996;111:1418-1424.