Organic osmolyte transport in quiescent and activated rat hepatic stellate cells (Ito cells)

Hepatology

Volumn 29, Issue 1, 1999, Pages 173-180

  Peters Regehr, Thorsten ^a   Bode, Johannes G ^a   Kubitz, Ralf ^a   Häussinger, Dieter ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETAINE; CYCLOOXYGENASE 2; INOSITOL; MESSENGER RNA; TAURINE;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; FIBROGENESIS; ION TRANSPORT; ITO CELL; LIVER CELL; LIVER CELL CULTURE; LIVER FIBROSIS; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; RAT; STELLATE CELL;

ACTINS; ANIMALS; BETAINE; BIOLOGICAL TRANSPORT; BLOTTING, NORTHERN; CARRIER PROTEINS; CELL SEPARATION; CELLS, CULTURED; CYCLOOXYGENASE 2; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; INOSITOL; ISOENZYMES; LIVER; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; OSMOSIS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TAURINE;

EID: 0032946358     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290111     Document Type: Article

References (30)

1. Gressner AM. Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol 1995;22:28-32.
2. Ramadori G. The stellate cell (Ito-cell, fat storing cell, lipocyte, perisinusoidal cell) of the liver. Virchows Arch B Cell Pathol 1991;61:47-58.
3. Knook DL, De Leeuw AM. Isolation and characterization of fat storing cells from the rat liver. In: Knook DL, Wisse E, eds. Sinusoidal Liver Cells. Rijswijk, the Netherlands: Elsevier, 1982:45-52.
4. Gressner AM, Lotfi S, Gressner G, Haltner E, Kropf J. Synergism between hepatocytes and Kupffer cells in the activation of fat-storing cells (perisinusoidal lipocytes). J Hepatol 1993;19:117-132.
5. Ramadori G, Veit T, Schwögler S, Dienes HP, Knittel T, Rieder H, Meyer zum Büschenfelde K-H. Expression of the gene of the αt-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells. Virchows Arch B Cell Pathol 1990;59:349-357.
6. Rockey DC, Boyles JK, Cabbiani G, Friedmann SL. Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture. J Sub Cytol Pathol 1992;24:193-203.
7. 4-induced fibrotic rat livers. HEPATOLOGY 1996;23:1538-1545.
8. Kawada N, Klein H, Decker K. Eicosanoid-mediated contractility of HSCs. Biochem J 1992;285:367-371.
9. Gressner AM, Bachem MG. Cellular sources of noncollagenous matrix proteins: role of fat-storing cells in fibrogenesis. Semin Liver Dis 1990;10:0-46.
10. Schäfer S, Zerbe O, Gressner AM. The synthesis of proteoglycans in fat-storing cells of rat liver. HEPATOLOGY 1987;7:680-687.
11. Nakatsukasa H, Nagy P, Everts RP, Hsia R-P, Marsden E, Thorgeirsson SS. Cellular distribution of transforming growth factor-β 1 and procollagen types I, III, IV transcripts in carbon tetrachloride induced rat liver fibrosis. J Clin Invest 1990;85:1833-1843.
12. Friedmann SL. Cellular basis of hepatic fibrosis. N Engl J Med 1993;328:1828-1835.
13. Yancey PH, Burg MB. Distribution of major organic osmolytes in rabbit kidney during diuresis and antidiuresis. Am J Physiol 1989;257:F602-F607.
14. Nakanishi T, Turner RJ, Burg MB. Osmoregulation of betaine transport in mammalian renal medullary cells. Am J Physiol 1990;258:F1061-F1067.
15. Zhou C, Agarwal N, Cammata PR. Osmoregulatory changes in myoinositol transport by renal cells. Invest Opthalmol Vis Sci 1994;35:1236-1242.
16. Paredes A, McManus M, Kwon HM, Strange K. Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells. Am J Physiol 1993;263:C1282-C1288.
17. --dependent betaine transporter that is regulated by hypertonicity. Am J Physiol 1993;264:F20-F23.
18. Graf J. In: Lang F, Häussinger D, eds. Interaction of Cell Volume and Cell Function. Heidelberg: Springer Verlag, 1992:67-117.
19. Zhang F, Warskulat U, Wettstein M, Häussinger D. Identification of betaine as an osmolyte in rat liver macrophages (Kupffer cells). Gastroenterology 1996;110:1543-1552.
20. Warskulat U, Weik C, Hâussinger D. myo-inositol is an osmolyte in rat liver macrophages (Kupffer cells) but not in RAW 264,7 mouse macrophages. Biochem J 1997;326:289-295.
21. Warskulat U, Wettstein M, Häussinger D. Betaine is an osmolyte in RAW 264.7 RAW mouse macrophages. FEBS Lett 1995;377:47-50.
22. Warskulat U, Zhang F, Häussinger D. Modulation of phagocytosis by anisoosmolarity and betaine in rat liver macrophages (Kupffer cells) and RAW 264.7 mouse macrophages. FEBS Lett 1996;391:287-292.
23. Warskulat U, Wettstein M, Häussinger D. Osmoregulated taurine transport in H4IIE hepatoma cells perfuse rat liver. Biochem J 1997;321:683-690.
24. Weik C, Warskulat U, Bode J, Peters-Regehr T, Häussinger D. Compatible organic osmolytes in rat sinusoidal endothelial cells. HEPATOLOGY 1998;27:569-575.
25. Handler JS, Kwon HM. Regulation of renal cell organic osmolyte transport by tonicity. Am J Physiol 1993;265:C1449-C1455.
26. Burg MB. Molecular basis for osmoregulation of organic osmolytes in renal medullary cells. J Exp Zool 1994;268:171-175.
27. Chamberlain ME, Strange K. Anisomotic cell volume regulation: a comparative view. Am J Physiol 1989;257:C159-C173.
28. Schulz WA, Hallbrucker C, Eickelmann P, Sies H, Häussinger D. Increase of β-actin mRNA upon hypotonie perfusion of perfused rat liver. FEBS Lett 1991;292:264-266.
29. Offensperger WB, Offensperger S, Stoll B, Gerok W, Häussinger D. Effects of anisotonic exposure on duck hepatitis B virus replication HEPATOLOGY 1994;20:1-7.
30. Zhang F, Warskulat U, Häussinger D. Modulation of tumor necrosis factor-α release by anisoosmolarity and betaine release in rat liver macrophages (Kupffer cells). FEBS Lett 1996;391:293-296.